Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases

scientific article published on 8 June 2016

Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.SCR.2016.06.003
P932PMC publication ID5009183
P698PubMed publication ID27318155

P50authorAlessandro RosaQ41002249
P2093author name stringRiccardo De Santis
Irene Bozzoni
Cristina Limatola
Silvia Di Angelantonio
Francesca Pagani
Jessica Lenzi
P2860cites workSkeletal Muscle Is a Primary Target of SOD1G93A-Mediated ToxicityQ62397259
An efficient and reversible transposable system for gene delivery and lineage-specific differentiation in human embryonic stem cellsQ84519931
Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS modelQ24631645
State of play in amyotrophic lateral sclerosis geneticsQ26864816
Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.Q27303723
Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitroQ27324593
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosisQ28131805
Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neuronsQ28298056
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neuronsQ29616199
Onset and progression in inherited ALS determined by motor neurons and microgliaQ29619515
Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashionQ30532680
Epigenetic reprogramming of human embryonic stem cells into skeletal muscle cells and generation of contractile myospheres.Q30538794
Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic miceQ33832905
miR-373 is regulated by TGFβ signaling and promotes mesendoderm differentiation in human Embryonic Stem Cells.Q33844889
Modeling ALS with iPSCs reveals that mutant SOD1 misregulates neurofilament balance in motor neuronsQ34503763
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosisQ35540066
A functionally characterized test set of human induced pluripotent stem cellsQ35588556
ALS mutant FUS proteins are recruited into stress granules in induced pluripotent stem cell-derived motoneuronsQ35802889
Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerabilityQ35889309
Mutant SOD1 in cell types other than motor neurons and oligodendrocytes accelerates onset of disease in ALS mice.Q36677109
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegenerationQ37733168
Understanding ALS: new therapeutic approaches.Q38065343
Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanismsQ38853070
Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neuronsQ39007648
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutationQ39910909
Fusion-independent expression of functional ACh receptors in mouse mesoangioblast stem cells contacting muscle cellsQ40524044
Myogenic differentiation of muscular dystrophy-specific induced pluripotent stem cells for use in drug discoveryQ41956611
Derivation of Skeletal Myogenic Precursors from Human Pluripotent Stem Cells Using Conditional Expression of PAX7.Q42181288
A regulatory circuitry comprised of miR-302 and the transcription factors OCT4 and NR2F2 regulates human embryonic stem cell differentiationQ42578044
Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy.Q42819955
Drug screening for ALS using patient-specific induced pluripotent stem cellsQ42820289
Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS MiceQ46254778
Rodent models of amyotrophic lateral sclerosis.Q51822707
Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells.Q53506908
P4510describes a project that usesImageJQ1659584
P433issue1
P921main subjectamyotrophic lateral sclerosisQ206901
skeletal muscle cellQ66505052
P304page(s)140-147
P577publication date2016-06-08
P1433published inStem Cell ResearchQ15762171
P1476titleDifferentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases
P478volume17

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described by source (P1343)
Q98129323SAPi002-A
Q98129326SAPi003-A
Q98129329SAPi004-A

cites work (P2860)
Q94487112Acute conversion of patient-derived Duchenne muscular dystrophy iPSC into myotubes reveals constitutive and inducible over-activation of TGFβ-dependent pro-fibrotic signaling
Q92794366C9ORF72-related cellular pathology in skeletal myocytes derived from ALS-patient induced pluripotent stem cells
Q47680582FUS Mutant Human Motoneurons Display Altered Transcriptome and microRNA Pathways with Implications for ALS Pathogenesis.
Q99637145Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression
Q38429049In Vitro Innervation as an Experimental Model to Study the Expression and Functions of Acetylcholinesterase and Agrin in Human Skeletal Muscle
Q41230060Mechanically patterned neuromuscular junctions-in-a-dish have improved functional maturation
Q52585184Messenger RNA Delivery for Tissue Engineering and Regenerative Medicine Applications.
Q38430493Modelling FUS Mislocalisation in an In Vitro Model of Innervated Human Muscle.
Q64238282Quantification of human neuromuscular function through optogenetics
Q92747686iPSCs: A powerful tool for skeletal muscle tissue engineering

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