Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function

scientific article published on 9 May 2017

Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FREERADBIOMED.2017.05.008
P932PMC publication ID5489050
P698PubMed publication ID28499911

P2093author name stringJian-Mei Li
Lampson M Fan
Li Geng
Gavin Brooks
Junjie Du
Sarah Cahill-Smith
P2860cites workBiochemistry, physiology, and pathophysiology of NADPH oxidases in the cardiovascular systemQ26991619
Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide productionQ28114945
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Endothelial cell-specific reactive oxygen species production increases susceptibility to aortic dissectionQ30842247
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Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cellsQ33772599
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Nox4 is a protective reactive oxygen species generating vascular NADPH oxidaseQ34264162
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Novel isoforms of NADPH oxidase in vascular physiology and pathophysiologyQ35608862
Obesity-induced oxidative stress, accelerated functional decline with age and increased mortality in miceQ35685027
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Vascular NADPH oxidases: molecular mechanisms of activation.Q35994483
Molecular composition and regulation of the Nox family NAD(P)H oxidasesQ36255498
Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidasesQ36663405
Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunctionQ36867557
Interactions between reactive oxygen species generated by contractile activity and aging in skeletal muscle?Q37111542
Weighty concerns: the growing prevalence of obesity among older adultsQ37621659
Evaluation of methods of detecting cell reactive oxygen species production for drug screening and cell cycle studiesQ38203697
Chronic cocaine-induced cardiac oxidative stress and mitogen-activated protein kinase activation: the role of Nox2 oxidase.Q39924913
Phenotypic properties and characteristics of superoxide production by mouse coronary microvascular endothelial cellsQ40793745
Inactivation of Adenosine A2A Receptor Attenuates Basal and Angiotensin II-induced ROS Production by Nox2 in Endothelial CellsQ41130750
Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53Q41268543
Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.Q41862776
Crucial roles of Nox2-derived oxidative stress in deteriorating the function of insulin receptors and endothelium in dietary obesity of middle-aged miceQ42218087
Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activationQ42965262
Cell-free assays: the reductionist approach to the study of NADPH oxidase assembly, or "all you wanted to know about cell-free assays but did not dare to ask".Q46614435
Calculated low-density lipoprotein cholesterol remains a viable and important test for screening and targeting therapy.Q51907081
Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species.Q53533036
P921main subjectendotheliumQ111140
P304page(s)940-951
P577publication date2017-05-09
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleAging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function
P478volume108

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cites work (P2860)
Q64953339Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice.
Q91737075Association Between Glucose Metabolism And Vascular Aging In Chinese Adults: A Cross-Sectional Analysis In The Tianning Cohort Study
Q64967146Cisplatin nephrotoxicity as a model of chronic kidney disease.
Q59329588Different age-independent effects of nutraceutical combinations on endothelium-mediated coronary flow reserve
Q89683113Differential Sensitivity of Two Endothelial Cell Lines to Hydrogen Peroxide Toxicity: Relevance for In Vitro Studies of the Blood-Brain Barrier
Q92898817Elevated Intraocular Pressure Causes Abnormal Reactivity of Mouse Retinal Arterioles
Q90392941Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro
Q55334122NADPH Oxidases and Mitochondria in Vascular Senescence.
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Q89475158Nox2 dependent redox-regulation of microglial response to amyloid-β stimulation and microgliosis in aging
Q46256490Troxerutin Reduces Kidney Damage against BDE-47-Induced Apoptosis via Inhibiting NOX2 Activity and Increasing Nrf2 Activity
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