A single divergent exon inhibits ankyrin-B association with the plasma membrane

scientific article published on 8 April 2013

A single divergent exon inhibits ankyrin-B association with the plasma membrane is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M113.465328
P932PMC publication ID3663501
P698PubMed publication ID23569209

P2093author name stringVann Bennett
Meng He
Wei-Chou Tseng
P2860cites workSpectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissuesQ24291372
Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytesQ24294117
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac deathQ24294267
A cardiac arrhythmia syndrome caused by loss of ankyrin-B functionQ24295030
Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomainQ24295272
Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytesQ24299734
Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathwayQ24305894
Lateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-GQ24306908
An ankyrin-based mechanism for functional organization of dystrophin and dystroglycanQ24310823
AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of RanvierQ24311821
Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryosQ24318309
Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytesQ24319636
Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2Q24523680
Crystal structure of a 12 ANK repeat stack from human ankyrinR.Q24539221
Localization and Structure of the Ankyrin-binding Site on  2-SpectrinQ27653198
Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin functionQ27678019
Structural requirements for association of neurofascin with ankyrinQ27867722
The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formationQ28292501
The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytesQ28510065
Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptorsQ28512363
Molecular composition of the node of Ranvier: identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segmentsQ28566036
Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-BQ28575960
Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domainQ28585311
Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescenceQ33302911
N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivoQ34012762
Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesionQ34013147
C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activityQ34285674
Isoform specificity among ankyrins. An amphipathic alpha-helix in the divergent regulatory domain of ankyrin-b interacts with the molecular co-chaperone Hdj1/Hsp40.Q34312369
Protein palmitoylation by a family of DHHC protein S-acyltransferasesQ34508328
Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.Q34577826
Exon organization and novel alternative splicing of the human ANK2 gene: implications for cardiac function and human cardiac diseaseQ34827043
Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growthQ35187190
A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly.Q35992656
Fodrin: axonally transported polypeptides associated with the internal periphery of many cellsQ36205287
Golgi spectrin: identification of an erythroid beta-spectrin homolog associated with the Golgi complex.Q36234832
Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axonsQ36256346
The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequenceQ36798979
AnkyrinG is required for maintenance of the axon initial segment and neuronal polarity.Q36972640
AnkyrinG is required to maintain axo-dendritic polarity in vivoQ37394946
Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.Q37527235
Membrane domains based on ankyrin and spectrin associated with cell-cell interactionsQ37748235
Cysteine 70 of ankyrin-G is S-palmitoylated and is required for function of ankyrin-G in membrane domain assemblyQ39248845
Ankyrin-G promotes cyclic nucleotide-gated channel transport to rod photoreceptor sensory ciliaQ39870694
Molecular evolution of the ankyrin gene familyQ40373648
A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activityQ42496675
Cholinergic augmentation of insulin release requires ankyrin-B.Q43127221
Isoform specificity of ankyrin-B: a site in the divergent C-terminal domain is required for intramolecular associationQ46861699
Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathwayQ48354828
Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrinQ48898258
Ankyrin regulation: an alternatively spliced segment of the regulatory domain functions as an intramolecular modulatorQ67901993
Regulatory domains of erythrocyte ankyrinQ70187591
P4510describes a project that usesImageJQ1659584
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)14769-14779
P577publication date2013-04-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleA single divergent exon inhibits ankyrin-B association with the plasma membrane
P478volume288

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cites work (P2860)
Q30610760A PIK3C3-ankyrin-B-dynactin pathway promotes axonal growth and multiorganelle transport
Q93060524Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels
Q37385297Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes
Q33937714Ankyrin-G palmitoylation and βII-spectrin binding to phosphoinositide lipids drive lateral membrane assembly
Q47906560Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions
Q40965361CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment
Q89605708Cargo hold and delivery: Ankyrins, spectrins, and their functional patterning of neurons
Q35037894Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABAA receptors.
Q89551637Mechanisms and Alterations of Cardiac Ion Channels Leading to Disease: Role of Ankyrin-B in Cardiac Function
Q92881910Neurodevelopmental mutation of giant ankyrin-G disrupts a core mechanism for axon initial segment assembly
Q33168257Novel Variant in the ANK2 Membrane-Binding Domain Is Associated With Ankyrin-B Syndrome and Structural Heart Disease in a First Nations Population With a High Rate of Long QT Syndrome
Q35884257Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis
Q35173196Structural basis of diverse membrane target recognitions by ankyrins
Q45892196Tetrodotoxin-resistant voltage-gated sodium channel Nav 1.8 constitutively interacts with ankyrin G.
Q48002945The evolving role of ankyrin-B in cardiovascular disease.
Q92823963βII-spectrin promotes mouse brain connectivity through stabilizing axonal plasma membranes and enabling axonal organelle transport

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