Dexamethasone suppresses gene expression and production of IL-13 by human mast cell line and lung mast cells

scientific article published on July 1998

Dexamethasone suppresses gene expression and production of IL-13 by human mast cell line and lung mast cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0091-6749(98)70064-8
P698PubMed publication ID9679857

P2093author name stringOkayama H
Shirato K
Saitoh H
Shimura S
Fushimi T
P2860cites workInterleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell functionQ24563054
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responsesQ28115227
Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cellsQ28237381
Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokinesQ28253247
Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA.Q33554129
Dexamethasone inhibits human interleukin 2 but not interleukin 2 receptor gene expression in vitro at the level of nuclear transcriptionQ34189072
Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokinesQ36356540
Activated mast cells produce interleukin 13.Q36364660
IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligandQ36696547
Regulation of IgE synthesis by cytokinesQ36970501
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transductionQ38317997
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity.Q40791336
Regulation of cytokine and cytokine receptor expression by glucocorticoidsQ41224382
Establishment of an immature mast cell line from a patient with mast cell leukemiaQ41296878
Induction of human IgE synthesis in B cells by mast cells and basophilsQ41526881
Airway mucosal inflammation even in patients with newly diagnosed asthma.Q51670975
Disposition of synthetic glucocorticoids I. Pharmacokinetics of dexamethasone in healthy adultsQ52437050
Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophoresQ59052484
Production of the haemopoietic growth factors GM-CSF and interleukin-3 by mast cells in response to IgE receptor-mediated activationQ59070205
Glucocorticoids suppress the production of interleukin 4 by human lymphocytesQ68007100
Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthmaQ68052191
Dose-dependent pharmacokinetics of dexamethasoneQ69512893
Allergen-induced recruitment of bronchoalveolar helper (OKT4) and suppressor (OKT8) T-cells in asthma. Relative increases in OKT8 cells in single early responders compared with those in late-phase respondersQ70037295
Assessment of the anti-c-kit monoclonal antibody YB5.B8 in affinity magnetic enrichment of human lung mast cellsQ71614441
Dexamethasone suppressed gene expression and production of interleukin-10 by human peripheral blood mononuclear cells and monocytesQ71938372
Glucocorticoids suppressed production and gene expression of interleukin-5 by peripheral blood mononuclear cells in atopic patients and normal subjectsQ72001565
Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthmaQ72900769
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmast cellQ191989
dexamethasoneQ422252
P1104number of pages9
P304page(s)134-142
P577publication date1998-07-01
P1433published inThe Journal of Allergy and Clinical ImmunologyQ7743550
P1476titleDexamethasone suppresses gene expression and production of IL-13 by human mast cell line and lung mast cells
P478volume102

Reverse relations

cites work (P2860)
Q73195256Anti-inflammatory effects of peripheral benzodiazepine receptor ligands in two mouse models of inflammation
Q42522030Dexamethasone inhibits maturation, cytokine production and Fc epsilon RI expression of human cord blood-derived mast cells
Q78719231Do complex conditions require complex treatment?
Q46057096Effect of interleukin 13 on bronchial hyperresponsiveness and the bronchoprotective effect of beta-adrenergic bronchodilators and corticosteroids
Q47825836Effects of glucocorticoid on IL-13-induced Muc5ac expression in airways of mice.
Q40615991Inhibition by dexamethasone of interleukin 13 production via glucocorticoid receptor-mediated inhibition of c-Jun phosphorylation
Q47548202Inhibitory effect of naringenin via IL-13 level regulation on thymic stromal lymphopoietin-induced inflammatory reactions.
Q53064103Mast cell migration to airway smooth muscle in asthma. Can we Gro(w) something to block the attraction?
Q28084141Mast cell production and response to IL-4 and IL-13
Q42831493Mast cells can revert dexamethasone-mediated down-regulation of stem cell factor
Q33979002Regulation of mast cell number and function
Q31766455Secretion and gene expression of secretory leukocyte protease inhibitor by human airway submucosal glands
Q40048581The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2.
Q92187895The Intriguing Role of Interleukin 13 in the Pathophysiology of Asthma
Q37010493The mast cell and allergic diseases: role in pathogenesis and implications for therapy
Q24795598Titanium dioxide particle-induced goblet cell hyperplasia: association with mast cells and IL-13

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