Functional Similarities between the Protein O-Mannosyltransferases Pmt4 from Bakers' Yeast and Human POMT1.

scientific article published on 29 June 2016

Functional Similarities between the Protein O-Mannosyltransferases Pmt4 from Bakers' Yeast and Human POMT1. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M116.739128
P932PMC publication ID5016187
P698PubMed publication ID27358400

P2093author name stringThomas Jank
Jakob Engel
Sabine Strahl
Daniela Bausewein
Maria Schoedl
P2860cites workDemonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activityQ24303491
Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndromeQ24561808
POMT2 mutations cause alpha-dystroglycan hypoglycosylation and Walker-Warburg syndromeQ24674153
Arabidopsis Stromal-derived Factor2 (SDF2) Is a Crucial Target of the Unfolded Protein Response in the Endoplasmic ReticulumQ27660462
A conserved acidic motif is crucial for enzymatic activity of protein O-mannosyltransferasesQ27931927
Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselvesQ27932724
PMT3 and PMT4, two new members of the protein-O-mannosyltransferase gene family of Saccharomyces cerevisiaeQ27934324
Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic reticulumQ27937605
Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolasesQ27937990
PMT1, the gene for a key enzyme of protein O-glycosylation in Saccharomyces cerevisiaeQ27939342
Protein-O-glycosylation in yeast: protein-specific mannosyltransferasesQ27939644
Refining genotype phenotype correlations in muscular dystrophies with defective glycosylation of dystroglycanQ28249364
Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethalityQ28512333
Novel repeats in ryanodine and IP3 receptors and protein O-mannosyltransferasesQ30837501
Regulation of mammalian protein O-mannosylation: preferential amino acid sequence for O-mannose modificationQ33284581
An autosomal recessive limb girdle muscular dystrophy (LGMD2) with mild mental retardation is allelic to Walker-Warburg syndrome (WWS) caused by a mutation in the POMT1 geneQ34406665
Physical and functional association of human protein O-mannosyltransferases 1 and 2.Q34525616
Protein O-mannosylation: conserved from bacteria to humansQ34980261
Membrane association is a determinant for substrate recognition by PMT4 protein O-mannosyltransferasesQ35808740
Mapping the O-Mannose Glycoproteome in Saccharomyces cerevisiaeQ36778284
Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesionQ37421256
Mining the O-mannose glycoproteome reveals cadherins as major O-mannosylated glycoproteinsQ37421355
Protein O-mannosyltransferases associate with the translocon to modify translocating polypeptide chains.Q37653341
Dystroglycanopathies: coming into focusQ37852376
Protein O-mannosylation: what we have learned from baker's yeastQ38084038
Mammalian O-mannosylation pathway: glycan structures, enzymes, and protein substratesQ38208557
The twisted abdomen phenotype of Drosophila POMT1 and POMT2 mutants coincides with their heterophilic protein O-mannosyltransferase activityQ38338552
O-mannosylation: The other glycan player of ER quality controlQ38349708
Initiation of mammalian O-mannosylation in vivo is independent of a consensus sequence and controlled by peptide regions within and upstream of the alpha-dystroglycan mucin domainQ39985380
DMSO-enhanced whole cell yeast transformationQ40508044
O-mannosylation precedes and potentially controls the N-glycosylation of a yeast cell wall glycoprotein.Q40773041
The PMT gene family: protein O-glycosylation in Saccharomyces cerevisiae is vitalQ41077782
The expanding phenotype of POMT1 mutations: from Walker-Warburg syndrome to congenital muscular dystrophy, microcephaly, and mental retardation.Q41919724
POMT1 is Essential for Protein O-Mannosylation in MammalsQ42917956
O-glycosylation of the non-canonical T-cadherin from rabbit skeletal muscle by single mannose residuesQ43528757
Protein O-glycosylation in Saccharomyces cerevisiae. Purification and characterization of the dolichyl-phosphate-D-mannose-protein O-D-mannosyltransferaseQ44029850
Different roles of the two components of human protein O-mannosyltransferase, POMT1 and POMT2.Q44971929
POMT1-associated walker-warburg syndrome: a disorder of dendritic development of neocortical neurons.Q45917058
Protein O-mannosylation is crucial for cell wall integrity, septation and viability in fission yeastQ46539201
Analysis of phenotype, enzyme activity and genotype of Chinese patients with POMT1 mutationQ48021354
Correlation of enzyme activity and clinical phenotype in POMT1-associated dystroglycanopathiesQ48348730
Members of protein O-mannosyltransferase family in Aspergillus fumigatus differentially affect growth, morphogenesis and viability.Q52599841
Transmembrane topology of pmt1p, a member of an evolutionarily conserved family of protein O-mannosyltransferasesQ56902293
A new Dol-P-Man:protein O-D-mannosyltransferase activity from Saccharomyces cerevisiaeQ72292504
Structure-function analysis of the dolichyl phosphate-mannose: protein O-mannosyltransferase ScPmt1pQ73675898
Involvement of dolicholmonophosphate in the formation of specific mannosyl-linkages in yeast glycoproteinsQ93749225
P4510describes a project that usesImageQuantQ112270642
P433issue34
P407language of work or nameEnglishQ1860
P304page(s)18006-18015
P577publication date2016-06-29
P1433published inJournal of Biological ChemistryQ867727
P1476titleFunctional Similarities between the Protein O-Mannosyltransferases Pmt4 from Bakers' Yeast and Human POMT1.
P478volume291

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cites work (P2860)
Q36396717Cellular Consequences of Diminished Protein O-Mannosyltransferase Activity in Baker's Yeast
Q47705231Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins.
Q54957953Impairment of photoreceptor ribbon synapses in a novel Pomt1 conditional knockout mouse model of dystroglycanopathy.
Q33882060Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2.
Q57471896Monitoring Protein Dynamics in Protein -Mannosyltransferase Mutants In Vivo by Tandem Fluorescent Protein Timers

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