Development of a Cell-penetrating Peptide that Exhibits Responsive Changes in its Secondary Structure in the Cellular Environment.

scientific article published on 9 September 2016

Development of a Cell-penetrating Peptide that Exhibits Responsive Changes in its Secondary Structure in the Cellular Environment. is …
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scholarly articleQ13442814

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P356DOI10.1038/SREP33003
P932PMC publication ID5016780
P698PubMed publication ID27609319

P50authorYosuke DemizuQ47404861
Makoto ObaQ53179177
Takuma KatoQ59699906
Mikihiko NaitoQ87965791
Takayuki HattoriQ114390247
Nobumichi OhokaQ114392722
P2093author name stringMasaaki Kurihara
Masakazu Tanaka
Hiroko Yamashita
Takashi Misawa
P2860cites workApplication of a fusiogenic peptide GALA for intracellular deliveryQ45067465
Effects of conformational stability and geometry of guanidinium display on cell entry by beta-peptidesQ46383269
4(R/S)-Guanidinylprolyl Collagen Peptides: On-Resin Synthesis, Complexation with Plasmid DNA, and the Role of Peptides in Enhancement of TransfectionQ46417611
Cell penetrating agents based on a polyproline helix scaffoldQ46653765
Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycansQ46758321
A rigid helical peptide axle for a [2]rotaxane molecular machine.Q47589624
Cytosolic targeting of macromolecules using a pH-dependent fusogenic peptide in combination with cationic liposomesQ47957098
Privileged delivery of polymer nanoparticles to the perinuclear region of live cells via a non-clathrin, non-degradative pathwayQ51046784
Collagen-like cell-penetrating peptides.Q51064863
Amphipathic short helix-stabilized peptides with cell-membrane penetrating ability.Q53060930
Oligopeptides with equal amounts of L- and D-amino acids may prefer a helix screw sense.Q54660283
Induction of Unexpected Left-Handed Helicity by an N-Terminal L-Amino Acid in an Otherwise Achiral Peptide ChainQ59606079
Interaction and structure induction of cell-penetrating peptides in the presence of phospholipid vesiclesQ63347063
Flexible-geometry conformational energy maps for the amino acid residue preceding a prolineQ67598275
Intrinsically cell-permeable miniature proteins based on a minimal cationic PPII motifQ81553281
Screw-sense control of helical oligopeptides containing equal amounts of L- and D-amino acidsQ84952843
Cell-penetrating helical peptides having l-arginines and five-membered ring α,α-disubstituted α-amino acidsQ85250487
A Helix-Stabilized Cell-Penetrating Peptide as an Intracellular Delivery ToolQ86686015
Conformational change of Sos-derived proline-rich peptide upon binding Grb2 N-terminal SH3 domain probed by NMR.Q30009546
Polyproline-II Helix in Proteins: Structure and FunctionQ30009896
Secondary structure and position of the cell-penetrating peptide transportan in SDS micelles as determined by NMR.Q30640608
A novel IRQ ligand-modified nano-carrier targeted to a unique pathway of caveolar endocytic pathwayQ33308413
Intracellular internalization mechanism of protein transfection reagents.Q34335056
Dual peptide conjugation strategy for improved cellular uptake and mitochondria targetingQ35013447
GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene deliveryQ35739328
Fluorescence correlation spectroscopy reveals highly efficient cytosolic delivery of certain penta-arg proteins and stapled peptidesQ36428998
Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA deliveryQ36815546
Proline-rich, amphipathic cell-penetrating peptidesQ37054611
Proline residues in transmembrane helices: structural or dynamic role?Q37301112
Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environmentQ37536870
Plasmid DNA delivery by arginine-rich cell-penetrating peptides containing unnatural amino acidsQ38774123
Trichogin GA IV: a versatile template for the synthesis of novel peptaibiotics.Q39426260
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptidesQ39481919
Reverse turns in peptides and proteins.Q40294614
Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfectionQ40813285
X-ray crystallography of peptides: the contributions of the Italian laboratoriesQ40934670
A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptidesQ41034490
Arginine Topology Controls Escape of Minimally Cationic Proteins from Early Endosomes to the CytoplasmQ41500169
Conservation of polyproline II helices in homologous proteins: implications for structure prediction by model buildingQ41869924
Practical and efficient synthesis of orthogonally protected constrained 4-guanidinoprolinesQ43656321
Controls exerted by the Aib residue: helix formation and helix reversalQ44062237
Quantitative correlation of solvent polarity with the alpha-/3(10)-helix equilibrium: a heptapeptide behaves as a solvent-driven molecular springQ44531122
Two prolines with a difference: contrasting stereoelectronic effects of 4R/S-aminoproline on triplex stability in collagen peptides [pro(X)-pro(Y)-Gly]nQ44640055
Conformations of proline residues in membrane environmentsQ44854552
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)33003
P577publication date2016-09-09
P1433published inScientific ReportsQ2261792
P1476titleDevelopment of a Cell-penetrating Peptide that Exhibits Responsive Changes in its Secondary Structure in the Cellular Environment
P478volume6