Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells

scientific article

Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.273.9.4909
P698PubMed publication ID9478934

P2093author name stringTong Q
Jhiang SM
Xing S
Furminger TL
P2860cites workActivation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2BQ24309625
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase CgammaQ24310718
A GPI-linked protein that interacts with Ret to form a candidate neurturin receptorQ24311883
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNFQ24329169
Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factorQ24561804
Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase AQ24611227
Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7Q28278965
Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinaseQ28283499
Identification of Shc docking site on Ret tyrosine kinaseQ28304464
Catalytic specificity of protein-tyrosine kinases is critical for selective signallingQ29616451
Mitogen-activated protein kinase pathwaysQ29618431
Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutationsQ36550021
An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathwayQ36644261
A potential pathogenetic mechanism for multiple endocrine neoplasia type 2 syndromes involves ret-induced impairment of terminal differentiation of neuroepithelial cells.Q37451018
Regulatory elements in the promoter region of vgf, a nerve growth factor-inducible geneQ37599132
Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.Q41105131
Glial cell line-derived neurotrophic factor induces Ret-mediated lamellipodia formationQ41135268
Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinaseQ41166310
GDNF signalling through the Ret receptor tyrosine kinaseQ41190484
Functional receptor for GDNF encoded by the c-ret proto-oncogeneQ41190489
Leucine zipper-mediated dimerization is essential for the PTC1 oncogenic activityQ42801886
A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteinsQ42810812
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domainQ42812834
Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutationsQ44233386
Mutations of theRET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and Hirschsprung diseaseQ57591326
Nerve growth factor stimulates GAP-43 expression in PC12 cell clones independently of neurite outgrowthQ71604294
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectphaeochromocytomaQ536269
P304page(s)4909-4914
P577publication date1998-02-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleSignal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells
P478volume273

Reverse relations

cites work (P2860)
Q33757079Activated Alk triggers prolonged neurogenesis and Ret upregulation providing a therapeutic target in ALK-mutated neuroblastoma
Q40726263Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways
Q35445077Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer
Q24563513Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells
Q40852922Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor
Q40313679Cholecystokinin 1 receptor modulates the MEKK1-induced c-Jun trans-activation: structural requirements of the receptor
Q40655621Corticotropin‐Releasing Hormone (CRH) Expression and Protein Kinase A Mediated CRH Receptor Signalling in an Immortalized Hypothalamic Cell Line
Q40835424Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins
Q50067512Genetic and Epigenetic of Medullary Thyroid Cancer
Q55008552Genetic and Epigenetic of Medullary Thyroid Cancer.
Q40688618Glial cell line-derived neurotrophic factor and chronic electrical stimulation prevent VIII cranial nerve degeneration following denervation
Q36729440HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in vivo
Q40654307Internalization of glial cell-derived neurotrophic factor receptor GFR alpha 1 in the absence of the ret tyrosine kinase coreceptor
Q44004710Mutational and immunohistochemical study of the PI3K/Akt pathway in papillary thyroid carcinoma in Greece
Q35170203Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury
Q42792243Nuclear envelope irregularity is induced by RET/PTC during interphase
Q42795947Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells
Q34360698The GDNF/RET signaling pathway and human diseases
Q38814755The RET E616Q Variant is a Gain of Function Mutation Present in a Family with Features of Multiple Endocrine Neoplasia 2A.
Q34103632The RET proto-oncogene in human cancers
Q34565449The contribution of associated congenital anomalies in understanding Hirschsprung's disease
Q44224232The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation
Q34012396The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis
Q28141552The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas

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