Selective modification at the N-terminal region of human growth hormone that shows antagonistic activity

scientific article published on June 1997

Selective modification at the N-terminal region of human growth hormone that shows antagonistic activity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0303-7207(97)00084-1
P698PubMed publication ID9220030

P2093author name stringGuy R
Djiane J
Gertler A
Vogel T
Goffin V
Tchelet A
Helman D
Neospouolus C
P2860cites workHuman growth hormone and extracellular domain of its receptor: crystal structure of the complexQ24308045
The X-ray structure of a growth hormone-prolactin receptor complexQ24309612
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone moleculeQ28609946
A hot spot of binding energy in a hormone-receptor interfaceQ29547547
Binding in the growth hormone receptor complexQ33593803
Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytesQ34341892
Rational design of receptor-specific variants of human growth hormoneQ37486343
Preparation and characterization of recombinant prolactin receptor extracellular domain from rat.Q38288906
Extracellular domain of prolactin receptor from bovine mammary gland: expression in Escherichia coli, purification and characterization of its interaction with lactogenic hormonesQ38298335
Variation among species in the endocrine control of mammary growth and function: the roles of prolactin, growth hormone, and placental lactogenQ39734066
Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptorsQ40588516
Antagonistic properties of human prolactin analogs that show paradoxical agonistic activity in the Nb2 bioassayQ41185295
Selective modification of recombinant bovine placental lactogen by site-directed mutagenesis at its C terminusQ41217546
Human growth hormone fragments 1-43 and 44-191: in vitro somatogenic activity and receptor binding characteristics in human and nonprimate systemsQ41256445
Amino acid residues in the third alpha-helix of growth hormone involved in growth promoting activityQ41367083
Correlation between Prolactin-Receptor Interaction, Down-Regulation of Receptors, and Stimulation of Casein and Deoxyribonucleic Acid Biosynthesis in Rabbit Mammary Gland Explants*Q41552464
Rational design of potent antagonists to the human growth hormone receptorQ41618965
High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesisQ41824916
Receptor-mediated mitogenic action of prolactin in a rat lymphoma cell lineQ41921182
Interaction of lactogenic hormones with purified recombinant extracellular domain of rabbit prolactin receptor expressed in insect cellsQ42070273
Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interactionQ46931184
Use of a model to understand prolactin and growth hormone specificities.Q52321684
Receptor and antibody epitopes in human growth hormone identified by homolog-scanning mutagenesis.Q52485676
Site-directed mutations of human growth hormone that selectively modify its lactogenic activity and binding properties.Q54711676
Comparative study of in vitro and in vivo modulation of lactogenic and somatotropic receptors by native human growth hormone and its modified analog prepared by recombinant deoxyribonucleic acid technologyQ69056576
Characterization of lactogen receptors in lactogenic hormone-dependent and independent NB2 lymphoma cell linesQ69720993
Enhancement of human growth hormone-stimulated mitogenesis of Nb2 node lymphoma cells by 12-O-tetradecanoyl-phorbol-13-acetateQ70059309
Binding sites of human growth hormone and ovine and bovine prolactins in the mammary gland and the liver of lactating dairy cowQ70191038
Real-time kinetic measurements of the interactions between lactogenic hormones and prolactin-receptor extracellular domains from several species support the model of hormone-induced transient receptor dimerizationQ71515019
High-sensitivity sequencing with a gas-phase sequenatorQ71746421
Selective modification of human growth hormone by site-directed mutagenesis: implications for the diversity of biological actionsQ72195591
P433issue1-2
P304page(s)141-152
P577publication date1997-06-01
P1433published inMolecular and Cellular EndocrinologyQ1573600
P1476titleSelective modification at the N-terminal region of human growth hormone that shows antagonistic activity
P478volume130

Reverse relations

cites work (P2860)
Q40981883Cytokine-inducible SH2 protein (CIS3) and JAK2 binding protein (JAB) abolish prolactin receptor-mediated STAT5 signaling
Q33179850Functional heterodimerization of prolactin and growth hormone receptors by ovine placental lactogen
Q44327250Ovine placental lactogen specifically binds to endometrial glands of the ovine uterus.
Q40710321Preparation and expression of biologically active prolactin and growth hormone receptors and suppressor of cytokine signaling proteins 1, 2, 3, and 6 tagged with cyan and yellow fluorescent proteins
Q22254592Recombinant prolactin receptor extracellular domain of rainbow trout (Oncorhynchus mykiss): subcloning, preparation, and characterization
Q74602375Ruminant placental lactogens act as antagonists to homologous growth hormone receptors and as agonists to human or rabbit growth hormone receptors

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