Characterization of the human thrombopoietin gene promoter. A possible role of an Ets transcription factor, E4TF1/GABP.

scientific article published on April 1997

Characterization of the human thrombopoietin gene promoter. A possible role of an Ets transcription factor, E4TF1/GABP. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.272.17.11361
P698PubMed publication ID9111044
P5875ResearchGate publication ID14107204

P2093author name stringHanda H
Hamasaki N
Kamura T
Kitajima S
P2860cites workDNA sequencing with chain-terminating inhibitorsQ22066207
Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietinQ24316187
cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifsQ24321852
A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†Q24605651
Four structurally distinct, non-DNA-binding subunits of human nuclear respiratory factor 2 share a conserved transcriptional activation domainQ24646953
Mammalian ets-1 and ets-2 genes encode highly conserved proteinsQ24647052
A simple and very efficient method for generating cDNA librariesQ27860461
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiQ27860728
Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an ETS domain activator of viral promotersQ28263072
Human thrombopoietin: gene structure, cDNA sequence, expression, and chromosomal localizationQ36018621
Elf-1 binds to a critical element in a second CD4 enhancerQ36666636
Molecular cloning and chromosomal localization of the human thrombopoietin gene.Q36723422
Transcriptional activation through ETS domain binding sites in the cytochrome c oxidase subunit IV geneQ36747690
CCAAT-enhancer binding protein: a component of a differentiation switchQ37624411
Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complexQ38333812
GABP mediates insulin-increased prolactin gene transcriptionQ38358044
Current status of cytogenetic studies in animal tumors with special reference to nonrandom chromosome changesQ40327477
The Ets family of transcription factorsQ40871575
GABP and PU.1 compete for binding, yet cooperate to increase CD18 (beta 2 leukocyte integrin) transcriptionQ41283980
Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.Q41457316
cMpl ligand is a humoral regulator of megakaryocytopoiesisQ41460906
Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.Q41460921
Evolutionarily conserved Ets family members display distinct DNA binding specificitiesQ42125962
Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) geneQ46172413
Thrombopoietin is not responsible for the thrombocytosis observed in patients with acute myeloid leukemias and the 3q21q26 syndromeQ61150760
The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequenceQ68624466
Clinical correlations of the 3q21;q26 cytogenetic anomaly. A leukemic or myelodysplastic syndrome with preserved or increased platelet production and lack of response to cytotoxic drug therapyQ70043860
P433issue17
P407language of work or nameEnglishQ1860
P304page(s)11361-11368
P577publication date1997-04-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleCharacterization of the human thrombopoietin gene promoter. A possible role of an Ets transcription factor, E4TF1/GABP.
P478volume272

Reverse relations

cites work (P2860)
Q55067329An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia.
Q28215502Cell-cycle-dependent regulation of human aurora A transcription is mediated by periodic repression of E4TF1
Q33933227Ets target genes: past, present and future
Q39549399Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-kappaB enhancer element into a GABP binding site.
Q35676790Functional and structural profiling of the human thrombopoietin gene promoter
Q37482521Genetic variations in angiogenesis pathway genes associated with clinical outcome in localized gastric adenocarcinoma.
Q40177792Hepatocyte growth factor accelerates thrombopoiesis in transgenic mice
Q36242078Intron V, not intron I of human thrombopoietin, improves expression in the milk of transgenic mice regulated by goat beta-casein promoter
Q59808539Latent viruses can cause disease by disrupting the competition for the limiting factor p300/CBP
Q30179391METTL23, a transcriptional partner of GABPA, is essential for human cognition
Q48704998Modulation of the promoter region of prepro-hypocretin by alpha-interferon
Q34024065Multiple ETS family proteins regulate PF4 gene expression by binding to the same ETS binding site
Q24300004Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene
Q57607768Polymorphisms in the thrombopoietin gene are associated with risk of myocardial infarction at a young age
Q38328628Structures, sequence characteristics, and synteny relationships of the transcription factor E4TF1, the splicing factor U2AF35 and the cystathionine beta synthetase genes from Fugu rubripes
Q73580453The 4830C>A polymorphism within intron 5 affects the pattern of alternative splicing occurring within exon 6 of the thrombopoietin gene
Q36733021The ETS transcription factor GABPalpha is essential for early embryogenesis
Q34139373The Ets-transcription factor family in embryonic development: lessons from the amphibian and bird
Q24291486The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities
Q46784360The last intron of the human thrombopoietin gene enhances expression in milk of transgenic mice
Q54276966VEGFR-2, CXCR-2 and PAR-1 germline polymorphisms as predictors of survival in pancreatic carcinoma.
Q27935814p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation