7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross-reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-1.

scientific article published on March 1997

7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross-reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-1. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1161/01.ATV.17.3.528
P8608Fatcat IDrelease_bczzfx7wsbewfj4x32oa7m2fue
P698PubMed publication ID9102172

P2093author name stringXu H
Rogers C
Simon DI
Rao NK
Ortlepp S
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)528-535
P577publication date1997-03-01
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476title7E3 monoclonal antibody directed against the platelet glycoprotein IIb/IIIa cross-reacts with the leukocyte integrin Mac-1 and blocks adhesion to fibrinogen and ICAM-1.
P478volume17

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cites work (P2860)
Q37316783A bumpy and winding but right path to domestic drug-eluting coronary stents
Q36286707A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits
Q33392128A putative role for platelet-derived PPARγ in vascular homeostasis demonstrated by anti-PPARγ induction of bleeding, thrombocytopenia and compensatory megakaryocytopoiesis
Q77959634A risk-benefit assessment of abciximab in angioplasty
Q33504164Abciximab. An updated review of its use in ischaemic heart disease
Q37221177Anti-inflammatory effect of abciximab-coated stent in a porcine coronary restenosis model
Q37929839Anti-platelet therapy: glycoprotein IIb-IIIa antagonists
Q43573530Antiplatelet effects of abciximab, tirofiban and eptifibatide in patients undergoing coronary stenting
Q34027525Antithrombotic therapy in the cardiac catheterization laboratory: focus on antiplatelet agents
Q34930685Bench to bedside: pathophysiology of acute coronary syndromes and implications for therapy
Q28483889Cardiopulmonary bypass during cardiac surgery modulates systemic inflammation by affecting different steps of the leukocyte recruitment cascade
Q33943133Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes
Q77958677Chimeric 7E3 Fab (ReoPro) decreases detectable CD11b on neutrophils from patients undergoing coronary angioplasty
Q28166129Comparative Pharmacology of GP IIb/IIIa Antagonists
Q42831038Darwin and the survival of the fittest in modern interventional cardiology.
Q33781957Development of eptifibatide
Q44563411Different effects of various anti-GPIIb-IIIa agents on shear-induced platelet activation and expression of procoagulant activity
Q34814479Do neutrophils contribute to myocardial reperfusion injury?
Q24796695Early recovery of microvascular perfusion induced by t-PA in combination with abciximab or eptifibatide during postischemic reperfusion
Q41765654Effect of abciximab on the levels of circulating microparticles in patients with acute myocardial infarction treated by primary angioplasty
Q33502054Effect of glycoprotein IIb/IIIa antagonists on the HIT serum induced activation of platelets
Q73156905Effect of glycoprotein IIb/IIIa receptor blockade on platelet-leukocyte interaction and surface expression of the leukocyte integrin Mac-1 in acute myocardial infarction
Q73583534Effect of glycoprotein IIb/IIIa receptor blockade with abciximab on clinical and angiographic restenosis rate after the placement of coronary stents following acute myocardial infarction
Q28165946Effects of 2 different antiplatelet regimens with abciximab or tirofiban on platelet function in patients undergoing coronary stenting
Q74709449Effects of abciximab pretreatment in patients with acute myocardial infarction undergoing primary angioplasty
Q38384596Effects of the P-Selectin Antagonist Inclacumab on Myocardial Damage After Percutaneous Coronary Intervention According to Timing of Infusion: Insights From the SELECT-ACS Trial.
Q34003157Endothelial cell delivery for cardiovascular therapy
Q81214093Eptifibatide: a review of its use in patients with acute coronary syndromes and/or undergoing percutaneous coronary intervention
Q42238584Evolving coronary stents coated with new bioactive agents
Q33502467Glycoprotein IIb/IIIa antagonists: potential induction and detection of drug-dependent antiplatelet antibodies
Q28193156Glycoprotein receptor inhibitors in the management of acute coronary syndromes
Q44916106Increase of myocardial salvage and left ventricular function recovery with intracoronary abciximab downstream of the coronary occlusion in patients with acute myocardial infarction treated with primary coronary intervention.
Q74016518Increased adhesiveness of white blood cells in patients with unstable angina: additional evidence for an involvement of the immune-inflammatory system
Q74172108Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease
Q36025986Inflammation as a mechanism and therapeutic target for in-stent restenosis
Q36369005Integrin alpha(M)beta(2)-mediated cell migration to fibrinogen and its recognition peptides
Q34912684Integrin targeted therapeutics
Q37011736Integrin αIIbβ3: from discovery to efficacious therapeutic target
Q81311780Intraarterial reteplase and intravenous abciximab for treatment of acute ischemic stroke. A preliminary feasibility and safety study in a non-human primate model
Q36557600Intracoronary administration of abciximab during percutaneous coronary interventions: should this be the routine and preferred approach?
Q37279917Intracoronary pharmacotherapy in the management of coronary microvascular dysfunction.
Q34051300Ischemic complications after percutaneous transluminal coronary angioplasty
Q43756320Leukocyte/endothelium activation and interactions during femoral percutaneous transluminal angioplasty
Q56944701Long-term mortality benefit with abciximab in patients undergoing percutaneous coronary intervention
Q30305538Management of Acute Ischemic Coronary Syndromes: The Present and Future
Q51798983Material‐induced tissue factor expression but not CD11b upregulation depends on the presence of platelets
Q35839059Molecular and cellular basis of restenosis after percutaneous coronary intervention: the intertwining roles of platelets, leukocytes, and the coagulation-fibrinolysis system
Q47761313Molecular identification of the cross-reacting epitope on alphaM beta2 integrin I domain recognized by anti-alphaIIb beta3 monoclonal antibody 7E3 and its involvement in leukocyte adherence
Q34236658Monoclonal antibody therapy
Q44346890Multi-year follow-up of abciximab therapy in three randomized, placebo-controlled trials of percutaneous coronary revascularization
Q36085620Newer agents in antiplatelet therapy: a review
Q37131840Optimal Duration of Coronary Ligation and Reperfusion for Reperfusion Injury Study in a Rat Model
Q33768927Overcoming thrombolytic resistance: rationale and initial clinical experience combining thrombolytic therapy and glycoprotein IIb/IIIa receptor inhibition for acute myocardial infarction
Q34001532Pathophysiology and therapeutic modification of thrombin generation in patients with coronary artery disease
Q35813673Percutaneous coronary intervention in diabetics
Q38547727Platelet GP IIb-IIIa Receptor Antagonists in Primary Angioplasty: Back to the Future
Q34282877Platelet aggregation inhibition with glycoprotein IIb--IIIa inhibitors
Q58173541Platelet glycoprotein IIb/IIIa receptor inhibition in primary angioplasty for acute myocardial infarction: The new paradigm of direct revascularization
Q53249126Platelet-monocyte cross talk and tissue factor expression in stable angina vs. unstable angina/non ST-elevation myocardial infarction.
Q33862443Platelets and restenosis
Q28572010Platelets modulate ischemia/reperfusion-induced leukocyte recruitment in the mesenteric circulation
Q34061211Potential future clinical applications for the GPIIb/IIIa antagonist, abciximab in thrombosis, vascular and oncological indications
Q37709401Predictive value of C-reactive protein after drug-eluting stent implantation
Q36679440Rationale for intracoronary administration of abciximab
Q34074021Redefining medical treatment in the management of unstable angina
Q38622747Renewal of mural thrombus releases plasma markers and is involved in aortic abdominal aneurysm evolution
Q45021856Rhodostomin, a disintegrin, inhibits adhesion of neutrophils to fibrinogen and attenuates superoxide production
Q33417854Targeting integrin and integrin signaling in treating thrombosis
Q40690209The GP IIb/IIIa inhibitor abciximab (c7E3) inhibits the binding of various ligands to the leukocyte integrin Mac-1 (CD11b/CD18, alphaMbeta2).
Q35584004The Role of Glycoprotein IIb/IIIa-Receptor Antagonists in Diabetics
Q35751058The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18
Q35936923The long-term clinical results of a platelet glycoprotein IIb/IIIa receptor blocker (Abciximab: Reopro) coated stent in patients with coronary artery disease
Q34675284The pharmacodynamics of parenteral glycoprotein IIb/IIIa inhibitors
Q64984430Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?
Q33754183Trials of glycoprotein IIb-IIIa inhibitors in non-ST-segment elevation acute coronary syndromes: applicability to the practice of medicine in the United States
Q36255960Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures
Q73538114[The efficacy of platelet IIb/IIIa receptor blockers in acute coronary syndromes]
Q40904514beta-Adrenergic agonist modulation of monocyte adhesion to airway epithelial cells in vitro

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