Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase.

scientific article published on 4 February 2015

Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JAC/DKV010
P932PMC publication ID4498294
P698PubMed publication ID25656411
P5875ResearchGate publication ID270591222

P50authorHelen C HailesQ57649410
Dimitrios EvangelopoulosQ58830872
Luis CucaQ40861163
P2093author name stringSanjib Bhakta
Tulika Munshi
Richard Angell
John M Ward
Thomas Pesnot
Joanna M Redmond
Arundhati Maitra
Juan D Guzman
Deborah Needham
Markus C Gershater
Heledd M Davies
Parisa N Mortazavi
Diana A Barrera
Eleanor D Lamming
Eleanor McMahon
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DEG 5.0, a database of essential genes in both prokaryotes and eukaryotesQ24655902
ATP-dependent MurE ligase in Mycobacterium tuberculosis: biochemical and structural characterisationQ27658363
Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosisQ27666292
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Characterization of the alanine racemases from two mycobacteriaQ28486479
Molecular field extrema as descriptors of biological activity: definition and validation.Q51945200
Morphological and biochemical changes in Escherichia coli after exposure to ciprofloxacin.Q54773512
Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolinesQ68694281
A relationship between ring substituents and absolute configuration in the aporphine series. The structures of thalicmidine and argemonineQ79416487
Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloidsQ83307557
Rapid methods for testing inhibitors of mycobacterial growthQ84075182
HIV coinfection in multidrug- and extensively drug-resistant tuberculosis results in high early mortalityQ84734382
Antimycobacterials from lovage root (Ligusticum officinale Koch)Q84815282
The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shapeQ28487135
Characterisation of ATP-dependent Mur ligases involved in the biogenesis of cell wall peptidoglycan in Mycobacterium tuberculosisQ28488668
New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge.Q30953370
An integrated surrogate model for screening of drugs against Mycobacterium tuberculosisQ34187856
Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assayQ34781823
Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kineticsQ35096913
Asymmetric synthesis of isoquinoline alkaloids.Q35834647
An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosisQ36852681
Bioactive pyridine-N-oxide disulfides from Allium stipitatumQ37395698
Alkaloids as potential anti-tubercular agentsQ37432457
Bioactive styryllactones and alkaloid from flowers of Goniothalamus laoticusQ39830029
Interference of Mycobacterium tuberculosis cell division by Rv2719c, a cell wall hydrolaseQ40237990
Susceptibility of mycobacterial D-alanyl-D-alanine synthetase to D-cycloserineQ42236391
Brevianamides with antitubercular potential from a marine-derived isolate of Aspergillus versicolorQ42715984
Antimycobacterial activity of bisbenzylisoquinoline alkaloids from Tiliacora triandra against multidrug-resistant isolates of Mycobacterium tuberculosisQ42720504
Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis.Q42933739
India reports cases of totally drug-resistant tuberculosisQ44306693
Key fragmentation patterns of aporphine alkaloids by electrospray ionization with multistage mass spectrometryQ44773229
Antimycobacterial compounds from Piper sanctumQ45202331
Dimeric Aporphine-Benzylisoquinoline and Aporphine-Pavine AlkaloidsQ47357388
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectMycobacterium tuberculosisQ130971
P304page(s)1691-1703
P577publication date2015-02-04
P1433published inJournal of Antimicrobial ChemotherapyQ6294770
P1476titleTetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase
P478volume70

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cites work (P2860)
Q92647920Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen
Q40463792Early diagnosis and effective treatment regimens are the keys to tackle antimicrobial resistance in tuberculosis (TB): A report from Euroscicon's international TB Summit 2016.
Q40506281Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana).
Q90396097Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis
Q49496057One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues
Q92815392The Pictet-Spengler Reaction Updates Its Habits

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