Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.

scientific article published on 3 November 2015

Hotspot TERT promoter mutations are rare events in testicular germ cell tumors. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1050775178
P356DOI10.1007/S13277-015-4317-Y
P698PubMed publication ID26526580

P50authorRui Manuel ReisQ49550849
Fatima BaltazarQ51599151
F M CárcanoQ84289404
Paula SoaresQ37840702
Daniel Onofre VidalQ43507414
Herlander MarquesQ47101515
P2093author name stringCristovam Scapulatempo Neto
Luiz Fernando Lopes
André van Helvoort Lengert
Camila Maria da Silva Martinelli
Eduardo Caetano Albino da Silva
Luisa Queiroz
P2860cites workStem cell factor activates telomerase in mouse mitotic spermatogonia and in primordial germ cells.Q48863717
Microsatellite instability, mismatch repair deficiency, and BRAF mutation in treatment-resistant germ cell tumors.Q51766708
Telomerase activity in germ cell cancers and mature teratomas.Q52175357
TERT promoter mutations in soft tissue sarcomas.Q53337795
TERT promoter mutations in clear cell renal cell carcinoma.Q54314475
Mutations of BRAF and RAS are rare events in germ cell tumours.Q54700314
International Germ Cell Consensus Classification: a prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative GroupQ56474871
Germ cell-like telomeric length homeostasis in nonseminomatous testicular germ cell tumorsQ74234890
An integrated map of genetic variation from 1,092 human genomesQ22122153
Hallmarks of Cancer: The Next GenerationQ22252312
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancerQ29417028
Highly recurrent TERT promoter mutations in human melanomaQ29614798
TERT promoter mutations in familial and sporadic melanomaQ29614920
Expression level of hTERT is regulated by somatic mutation and common single nucleotide polymorphism at promoter region in glioblastomaQ33917659
Alternative lengthening of telomeres: models, mechanisms and implicationsQ34107386
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomasQ34313648
Treatment of testicular cancer: a new and improved modelQ34568793
A phase II trial of TIP (paclitaxel, ifosfamide and cisplatin) given as second-line (post-BEP) salvage chemotherapy for patients with metastatic germ cell cancer: a medical research council trialQ36615043
Interpreting the international trends in testicular seminoma and nonseminoma incidence.Q36619297
Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs).Q36695151
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewalQ36762656
High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesionsQ37064910
TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphismQ37256055
Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas.Q37345320
TERT promoter mutations in cancer developmentQ38198430
Telomerase promoter mutations in cancer: an emerging molecular biomarker?Q38232447
Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer.Q38874534
Frequency of TERT promoter mutations in human cancersQ39120274
Short tandem repeat DNA typing provides an international reference standard for authentication of human cell lines.Q40410208
TERT promoter mutations in skin cancer: the effects of sun exposure and X-irradiation.Q42456732
Prognostic Factors in Patients With Metastatic Germ Cell Tumors Who Experienced Treatment Failure With Cisplatin-Based First-Line ChemotherapyQ42855201
Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR.Q44094702
Cisplatin and etoposide in childhood germ cell tumor: brazilian pediatric oncology society protocol GCT-91.Q46151039
P433issue4
P304page(s)4901-4907
P577publication date2015-11-03
P1433published inTumor BiologyQ15757842
P1476titleHotspot TERT promoter mutations are rare events in testicular germ cell tumors
P478volume37

Reverse relations

cites work (P2860)
Q47379639HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis
Q52620813Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.
Q26739948Telomerase: The Devil Inside
Q26739925Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene
Q38760235Understanding TERT Promoter Mutations: A Common Path to Immortality.

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