Evidence that a rapidly turning over protein, normally degraded by proteasomes, regulates hsp72 gene transcription in HepG2 cells

scientific article published on October 1996

Evidence that a rapidly turning over protein, normally degraded by proteasomes, regulates hsp72 gene transcription in HepG2 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.271.40.24769
P698PubMed publication ID8798747

P2093author name stringWu X
Zhou M
Ginsberg HN
P2860cites workSingle-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolutionQ27730197
Activation of human heat shock genes is accompanied by oligomerization, modification, and rapid translocation of heat shock transcription factor HSF1Q28118171
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I moleculesQ28248180
New insights into proteasome function: from archaebacteria to drug developmentQ28255512
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystinQ28300614
Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stressQ28609211
Heat shock gene regulation by nascent polypeptides and denatured proteins: hsp70 as a potential autoregulatory factorQ28609629
Protein folding in the cellQ29547792
Degradation of CFTR by the ubiquitin-proteasome pathwayQ29616142
The heat-shock responseQ29619473
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin BQ29620071
The induction of gene activity in drosophila by heat shockQ34068633
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptidesQ34172156
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Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injuryQ34206249
Transgenic mice expressing the human heat shock protein 70 have improved post-ischemic myocardial recoveryQ34211550
Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarctionQ34353028
Speculations on the functions of the major heat shock and glucose-regulated proteinsQ34562570
Protein folding in the cell: the role of molecular chaperones Hsp70 and Hsp60Q35836959
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In vivo inhibition of cyclin B degradation and induction of cell-cycle arrest in mammalian cells by the neutral cysteine protease inhibitor N-acetylleucylleucylnorleucinalQ36239496
Interaction between heat shock factor and hsp70 is insufficient to suppress induction of DNA-binding activity in vivoQ36666939
Activation of Drosophila heat shock factor: conformational change associated with a monomer-to-trimer transitionQ36686240
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cellsQ36848770
Heat shock, stress proteins, chaperones, and proteotoxicityQ37190844
Thermal response of rat fibroblasts stably transfected with the human 70-kDa heat shock protein-encoding geneQ37413488
Cardioprotective effects of 70-kDa heat shock protein in transgenic miceQ37692300
A new cleavable reagent for cross-linking and reversible immobilization of proteinsQ39255571
The role of molecular chaperones in protein transport into the endoplasmic reticulumQ40710001
Roles of molecular chaperones in protein targeting to mitochondriaQ40710008
Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. Evidence for increased cell viability and suppression of cytokine releaseQ41010028
Regulation of heat shock factor trimer formation: role of a conserved leucine zipperQ41578892
Phosphorylation of HSP27 during development and decay of thermotolerance in Chinese hamster cellsQ41688346
Cysteine proteinase inhibitors and ras gene products share the same biological activities including transforming activity toward NIH3T3 mouse fibroblasts and the differentiation-inducing activity toward PC12 rat pheochromocytoma cellsQ41748741
The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cellsQ42042449
Basal and inducible expression of metallothionein and heat shock protein 70 genes in bovine articular chondrocytesQ42507107
Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.Q45950874
Short circuiting stress protein expression via a tyrosine kinase inhibitor, herbimycin A.Q46653225
Influence of oxidative stress on induced tolerance to ischemia in gerbil hippocampal neuronsQ48393866
Differential distribution of 70-kD heat shock protein in atherosclerosis. Its potential role in arterial SMC survival.Q54186452
Constitutive expression of heat-shock protein 70 in mammalian cells confers thermoresistanceQ54293839
Heat-shock response is associated with enhanced postischemic ventricular recovery.Q54377036
P433issue40
P407language of work or nameEnglishQ1860
P304page(s)24769-24775
P577publication date1996-10-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleEvidence that a rapidly turning over protein, normally degraded by proteasomes, regulates hsp72 gene transcription in HepG2 cells
P478volume271

Reverse relations

cites work (P2860)
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Q33560278Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system
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