Increased release of the tumour necrosis factor receptor p75 by immortalized human keratinocytes results from an activated shedding mechanism and is not related to augmented steady-state levels of p75 mRNA.

scientific article published on October 1996

Increased release of the tumour necrosis factor receptor p75 by immortalized human keratinocytes results from an activated shedding mechanism and is not related to augmented steady-state levels of p75 mRNA. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S004030050125
P698PubMed publication ID8931872

P2093author name stringR Knobler
F Trautinger
G Klosner
M Pourmojib
P Neuner
P2860cites workModulation of squamous carcinoma cell growth, morphology, adhesiveness and extracellular matrix production by interferon-gamma and tumor necrosis factor-alphaQ68379351
In vivo T cell activation by anti-CD3 monoclonal antibody induces soluble TNF receptor release in mice. Effects of pentoxifylline, methylprednisolone, anti-TNF, and anti-IFN-gamma antibodiesQ72037662
Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor formsQ72775069
Soluble tumor necrosis factor receptor expression in patients with metastatic renal cell carcinoma treated with interleukin-2-based immunotherapyQ72964621
Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptorQ24304040
Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulenceQ28300302
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient miceQ28593915
Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptorQ33739657
A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitorQ33864621
Purification and characterization of an inhibitor (soluble tumor necrosis factor receptor) for tumor necrosis factor and lymphotoxin obtained from the serum ultrafiltrates of human cancer patientsQ33891111
Binding and biological effects of tumor necrosis factor alpha on cultured human neonatal foreskin keratinocytesQ34567983
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivoQ37031936
The 55-kD tumor necrosis factor receptor on human keratinocytes is regulated by tumor necrosis factor-alpha and by ultraviolet B radiationQ40333028
Characterization in vitro of a human tumor necrosis factor-binding protein. A soluble form of a tumor necrosis factor receptorQ40348334
IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell linesQ40776887
High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemiaQ41020010
Selective release of tumor necrosis factor binding protein II by malignant human epidermal cells reveals protection from tumor necrosis factor alpha-mediated cytotoxicityQ41429029
Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylationQ41508854
Elevated TNF receptor plasma concentrations in patients with rheumatoid arthritisQ41650994
Measurement of the soluble membrane receptors for tumor necrosis factor and lymphotoxin in the sera of patients with gynecologic malignancyQ46676462
Selective species specificity of tumor necrosis factor for toxicity in the mouse.Q49168975
Polypetide mediator networkQ59073978
Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosusQ61628148
Increased serum levels of soluble receptors for tumor necrosis factor in cancer patientsQ68256254
55-kd tumor necrosis factor receptor is expressed by human keratinocytes and plays a pivotal role in regulation of human keratinocyte ICAM-1 expressionQ68318344
P433issue11
P921main subjectTNFQ18032037
P304page(s)691-696
P577publication date1996-10-01
P1433published inArchives of Dermatological ResearchQ18616385
P1476titleIncreased release of the tumour necrosis factor receptor p75 by immortalized human keratinocytes results from an activated shedding mechanism and is not related to augmented steady-state levels of p75 mRNA.
P478volume288

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cites work (P2860)
Q40400235Transactivation of the EGF receptor in A431 human carcinoma cells upon exposure to heat shock
Q57826759UVA and UVB Radiation Differentially Regulate Vascular Endothelial Growth Factor Expression in Keratinocyte-derived Cell Lines and in Human Keratinocytes

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