Site-specific cleavage of G protein-coupled receptor-engaged beta-arrestin. Influence of the AT1 receptor conformation on scissile site selection

scientific article published on 27 May 2008

Site-specific cleavage of G protein-coupled receptor-engaged beta-arrestin. Influence of the AT1 receptor conformation on scissile site selection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M803062200
P932PMC publication ID2490789
P698PubMed publication ID18505723

P2093author name stringMijin Kim
Satya P Yadav
Sadashiva S Karnik
ChangWoo Lee
Anita Shukla
Sei-Heon Jang
Russell W Desnoyer
Sumantha Bhatt
P2860cites workBeta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexesQ22008730
Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffoldsQ24605173
Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane TranslocationQ27634946
Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3Q28138462
The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pitsQ28142257
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestinQ28190513
Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domainQ28239593
Transduction of receptor signals by beta-arrestinsQ28246395
A β-Arrestin/Green Fluorescent Protein Biosensor for Detecting G Protein-coupled Receptor ActivationQ28252768
Clathrin-mediated Endocytosis of the β-Adrenergic Receptor Is Regulated by Phosphorylation/Dephosphorylation of β-Arrestin1Q28255754
Polypeptide variants of beta-arrestin and arrestin3Q28611734
High-content screening of known G protein-coupled receptors by arrestin translocationQ33263835
Unconventional homologous internalization of the angiotensin II type-1 receptor induced by G-protein-independent signalsQ34099132
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.Q34536660
Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling.Q34982563
A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signalingQ36082162
Multiple signaling states of G-protein-coupled receptorsQ36138102
Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptorsQ36160942
Molecular-specific effects of angiotensin II antagonists: clinical relevance to treating hypertension?Q36223165
Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II.Q36248631
Characterization of a truncated form of arrestin isolated from bovine rod outer segmentsQ36278630
Review of the molecular pharmacology of Losartan and its possible relevance to stroke prevention in patients with hypertensionQ36543505
A splice variant of arrestin. Molecular cloning and localization in bovine retinaQ38307343
Visualization of agonist-induced association and trafficking of green fluorescent protein-tagged forms of both beta-arrestin-1 and the thyrotropin-releasing hormone receptor-1.Q38321972
Gonadotropin binding and stimulation of cyclic adenosine 3':5'-monophosphate and testosterone production in isolated Leydig cellsQ39957471
Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2.Q40601346
Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalizationQ41176691
Agonist-induced phosphorylation of the angiotensin II (AT(1A)) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling stateQ42482690
Association of beta-Arrestin 1 with the type 1A angiotensin II receptor involves phosphorylation of the receptor carboxyl terminus and correlates with receptor internalizationQ43752385
Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.Q43922018
Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptorsQ45133871
G protein-coupled receptors. I. Diversity of receptor-ligand interactionsQ47892279
Selective proteolysis of arrestin by calpain. Molecular characteristics and its effect on rhodopsin dephosphorylationQ48069882
The active state of the AT1 angiotensin receptor is generated by angiotensin II inductionQ71955400
Manifold active-state conformations in GPCRs: agonist-activated constitutively active mutant AT1 receptor preferentially couples to Gq compared to the wild-type AT1 receptorQ80324798
P433issue31
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)21612-21620
P577publication date2008-05-27
P1433published inJournal of Biological ChemistryQ867727
P1476titleSite-specific cleavage of G protein-coupled receptor-engaged beta-arrestin. Influence of the AT1 receptor conformation on scissile site selection
P478volume283

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cites work (P2860)
Q33660437A protein tyrosine phosphatase inhibitor, pervanadate, inhibits angiotensin II-Induced beta-arrestin cleavage
Q41774393Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.

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