Hepatoprotective Role of Hydrangea macrophylla against Sodium Arsenite-Induced Mitochondrial-Dependent Oxidative Stress via the Inhibition of MAPK/Caspase-3 Pathways.

scientific article published on 10 July 2017

Hepatoprotective Role of Hydrangea macrophylla against Sodium Arsenite-Induced Mitochondrial-Dependent Oxidative Stress via the Inhibition of MAPK/Caspase-3 Pathways. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/IJMS18071482
P932PMC publication ID5535972
P698PubMed publication ID28698525

P50authorMd Rashedunnabi AkandaQ49694298
P2093author name stringHyun-Jin Tae
Dongchoon Ahn
Byung-Yong Park
In-Shik Kim
Weishun Tian
Hyeon-Hwa Nam
Anowarul Islam
Byung-Kil Choo
P2860cites workThe multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: from respiration to apoptosisQ23917508
Heavy Metals and Human Health: Mechanistic Insight into Toxicity and Counter Defense System of AntioxidantsQ26774259
An Overview of Plant Phenolic Compounds and Their Importance in Human Nutrition and Management of Type 2 DiabetesQ28078920
Arsenic trioxide selectively induces acute promyelocytic leukemia cell apoptosis via a hydrogen peroxide-dependent pathwayQ28372372
Arsenic and cardiovascular diseaseQ28387404
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functionsQ29547189
Mitochondria and apoptosisQ29547905
Resveratrol, a natural antioxidant, has a protective effect on liver injury induced by inorganic arsenic exposureQ34043077
The global burden of liver disease: a challenge for methods and for public healthQ34207640
Environmental source of arsenic exposure.Q34293081
Arsenic-induced toxicity and the protective role of ascorbic acid in mouse testis.Q53582062
Arsenic induces apoptosis in mouse liver is mitochondria dependent and is abrogated by N-acetylcysteineQ57937301
Arsenite induces apoptosis in hepatocytes through an enhancement of the activation of Jun N-terminal kinase and p38 mitogen-activated protein kinase caused by partial hepatectomyQ79783205
The establishment of efficient bioconversion, extraction, and isolation processes for the production of phyllodulcin, a potential high intensity sweetener, from sweet hydrangea leaves (Hydrangea macrophylla Thunbergii)Q87328716
Caspase functions in cell death and diseaseQ34336335
An update on oxidative stress-mediated organ pathophysiologyQ34374613
Hydrangeic acid from the processed leaves of Hydrangea macrophylla var. thunbergii as a new type of anti-diabetic compoundQ34976389
Ameliorative effect of water spinach, Ipomea aquatica (Convolvulaceae), against experimentally induced arsenic toxicity.Q35176911
Unraveling the mechanism of neuroprotection of curcumin in arsenic induced cholinergic dysfunctions in rats.Q35192680
Effect of Sodium Arsenite on Mouse Skin CarcinogenesisQ35563733
Antioxidant potential, total phenolic and total flavonoid contents of Rhododendron anthopogonoides and its protective effect on hypoxia-induced injury in PC12 cellsQ35748443
Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways.Q35918916
Multiple pathways of cytochrome c release from mitochondria in apoptosisQ36470224
Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in miceQ37100770
Apoptosis and necrosis in the liverQ37403072
The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen PeroxideQ37424275
Arsenic-induced carcinogenesis--oxidative stress as a possible mode of action and future research needs for more biologically based risk assessmentQ37662780
Arsenic: toxicity, oxidative stress and human diseaseQ37842233
Mitochondrial dysfunctions and altered metals homeostasis: new weapons to counteract HCV-related oxidative stressQ38174062
Molecular mechanisms of hepatic apoptosisQ38179202
Flavonoids as important molecules of plant interactions with the environment.Q38259608
Arsenic and human health effects: A review.Q38610080
Dual role of resveratrol in modulation of genotoxicity induced by sodium arsenite via oxidative stress and apoptosis.Q39144997
Association of serum retinoic acid with hepatic steatosis and liver injury in nonalcoholic fatty liver diseaseQ41756969
Lipase-catalyzed synthesis of two new antioxidants: 4-O- and 3-O-palmitoyl chlorogenic acidsQ42920617
Comparison of antimalarial activity of the alkaloidal fraction of Hydrangea macrophylla var. Otaksa leaves with the hot-water extract in ICR mice infected with Plasmodium yoelii 17 XL.Q44486837
Determination of malonaldehyde precursor in tissues by thiobarbituric acid testQ44764466
Evaluation of DNA damage in patients with arsenic poisoning: urinary 8-hydroxydeoxyguanine.Q44994665
Anti-inflammatory activity of Chrysanthemum indicum extract in acute and chronic cutaneous inflammation.Q46017815
Taurine protects rat testes against NaAsO(2)-induced oxidative stress and apoptosis via mitochondrial dependent and independent pathways.Q46017954
Potential antioxidant properties and hepatoprotective effects of Juniperus phoenicea berries against CCl4 induced hepatic damage in rats.Q46227349
Prevention of arsenic-induced hepatic apoptosis by concomitant administration of garlic extracts in mice.Q46332402
Neuroprotective Effects of Sigesbeckia pubescens Extract on Glutamate-Induced Oxidative Stress in HT22 Cells via Downregulation of MAPK/caspase-3 Pathways.Q46370921
Attenuative role of mangiferin in oxidative stress-mediated liver dysfunction in arsenic-intoxicated murinesQ46473323
Serum activity of alanine aminotransferase (ALT) as an indicator of health and diseaseQ46682777
Hepatoprotective role and antioxidant capacity of selenium on arsenic-induced liver injury in rats.Q46766762
Anti-inflammatory, anticholinesterase and antioxidant activity of leaf extracts of twelve plants used traditionally to alleviate pain and inflammation in South AfricaQ46802677
Effects of sodium arsenate exposure on liver fatty acid profiles and oxidative stress in ratsQ47771139
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectHydrangea macrophyllaQ159219
P577publication date2017-07-10
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleHepatoprotective Role of Hydrangea macrophylla against Sodium Arsenite-Induced Mitochondrial-Dependent Oxidative Stress via the Inhibition of MAPK/Caspase-3 Pathways
P478volume18

Reverse relations

cites work (P2860)
Q64083181(Thunb.) Ser. Extract Attenuate UVB-Induced Photoaging through MAPK/AP-1 Inactivation in Human Skin Fibroblasts and Hairless Mice
Q49805411Anti-Inflammatory and Gastroprotective Roles of Rabdosia inflexa through Downregulation of Pro-Inflammatory Cytokines and MAPK/NF-κB Signaling Pathways
Q64971055Hydrangenol inhibits the proliferation, migration, and invasion of EJ bladder cancer cells via p21WAF1-mediated G1-phase cell cycle arrest, p38 MAPK activation, and reduction in Sp-1-induced MMP-9 expression.
Q49693969The Anti-Stress Effect of Mentha arvensis in Immobilized Rats

Search more.