Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho.

scientific article published on May 1996

Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ3160239
P932PMC publication ID1217328
P698PubMed publication ID8645211
P5875ResearchGate publication ID14555775

P50authorLimin ZhengQ51196796
Tommy AnderssonQ56741353
Eva GronroosQ57599358
P2093author name stringA Sjölander
A Schippert
P2860cites workG-protein alpha-subunit expression, myristoylation, and membrane association in COS cellsQ24559862
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Leukotrienes and lipoxins: structures, biosynthesis, and biological effectsQ29617543
G protein gamma subunits contain a 20-carbon isoprenoidQ33723497
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Protein prenylation: more than just glue?Q35659688
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Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinaseQ40792108
Regulation of phospholipase D in HL60 cells. Evidence for a cytosolic phospholipase D.Q41350502
The regulation of leukotriene D4-induced calcium influx in human epithelial cells involves protein tyrosine phosphorylation.Q41366282
Lovastatin inhibits receptor-stimulated Ca(2+)-influx in retinoic acid differentiated U937 and HL-60 cellsQ41445200
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho.Q41450596
Blockade of mevalonate production by lovastatin attenuates bombesin and vasopressin potentiation of nutrient-induced insulin secretion in HIT-T15 cells. Probable involvement of small GTP-binding proteins.Q41578279
Leukotriene D4 and E4 induce transmembrane signaling in human epithelial cells. Single cell analysis reveals diverse pathways at the G-protein level for the influx and the intracellular mobilization of Ca2+.Q41711066
Association of ligand-receptor complexes with actin filaments in human neutrophils: a possible regulatory role for a G-proteinQ42762220
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The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cellsQ46524862
Characterization of the guinea pig lung membrane leukotriene D4 receptor solubilized in an active form. Association and dissociation with an islet-activating protein-sensitive guanine nucleotide-binding protein.Q46791797
Analysis of the leukotriene D4 receptor in the granulation tissue of allergic inflammation in ratsQ46869801
Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.Q52512619
The establishment of strains of human cells in tissue culture.Q52831945
Regulation of ligand binding to leukotriene D4 receptors: effects of cations and guanine nucleotidesQ53907152
Angiotensin II stimulates tyrosine phosphorylation of phospholipase C-gamma 1 in vascular smooth muscle cellsQ57630626
Role of isoprenoid metabolism in IgE receptor-mediated signal transductionQ67899214
Characterization of the leukotriene D4 receptor in hyperreactive rat lungQ68242822
Leukotriene D4 binding and signal transduction in rat glomerular mesangial cellsQ69354431
Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein RhoQ72571161
Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinasesQ72645591
Activation of rat liver phospholipase D by the small GTP-binding protein RhoAQ72724467
P407language of work or nameEnglishQ1860
P1104number of pages7
P304page(s)239-245
P577publication date1996-05-01
P1433published inBiochemical JournalQ864221
P1476titleLeukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho
P478volume316 ( Pt 1)

Reverse relations

cites work (P2860)
Q40859818Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells
Q74801438Inhibition of Pollen Tube Elongation by Microinjected Anti-Rop1Ps Antibodies Suggests a Crucial Role for Rho-Type GTPases in the Control of Tip Growth
Q40891292Leukotriene D(4) triggers an association between gbetagamma subunits and phospholipase C-gamma1 in intestinal epithelial cells
Q24534194Leukotriene D4 induces association of active RhoA with phospholipase C-gamma1 in intestinal epithelial cells
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Q43797315Molecular cloning and functional characterization of murine cysteinyl-leukotriene 1 (CysLT(1)) receptors
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Q36492454Swelling-activated ion channels: functional regulation in cell-swelling, proliferation and apoptosis
Q41013953The inflammatory mediator leukotriene D4 triggers a rapid reorganisation of the actin cytoskeleton in human intestinal epithelial cells

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