Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human mo

scientific article published on April 1996

Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human mo is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ3150505
P932PMC publication ID1217224
P698PubMed publication ID8615821
P5875ResearchGate publication ID14584379

P2093author name stringMatsuo T
Ui M
Hazeki K
Hazeki O
Katada T
P2860cites workInterleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3'-kinaseQ24306141
T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motifQ24310233
Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signalingQ24563239
Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2Q24680231
The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptorQ28247924
Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursorsQ28287188
Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cblQ28294930
The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cellsQ28609032
The insulin signaling systemQ28615921
Oncogenes and signal transductionQ29547804
Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cellsQ30193317
Identification of the major tyrosine kinase substrate in signaling complexes formed after engagement of Fc gamma receptorsQ30193495
Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cellsQ30194870
Structure of 85 kDa subunit of human phosphatidylinositol 3-kinase analyzed by using monoclonal antibodiesQ30195126
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunitsQ34339415
After insulin bindsQ34398025
Fc receptor stimulation of phosphatidylinositol 3-kinase in natural killer cells is associated with protein kinase C-independent granule release and cell-mediated cytotoxicityQ36363884
Interleukin 7 receptor functions by recruiting the tyrosine kinase p59fyn through a segment of its cytoplasmic tailQ37350162
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.Q40478337
Structure, regulation and function of phosphoinositide 3-kinasesQ40685108
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?Q40859203
Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.Q40873048
Granulocyte macrophage-colony stimulating factor stimulates both association and activation of phosphoinositide 3OH-kinase and src-related tyrosine kinase(s) in human myeloid derived cellsQ40873320
Involvement of phosphatidylinositol 3-kinase in Fc gamma receptor signaling.Q41442812
T cell receptor-associated alpha-phosphatidylinositol 3-kinase becomes activated by T cell receptor cross-linking and requires pp56lckQ41453795
Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins.Q41486855
Phosphatidylinositol-3 kinase activation induced upon Fc gamma RIIIA-ligand interactionQ41489425
Erythropoietin-dependent association of phosphatidylinositol 3-kinase with tyrosine-phosphorylated erythropoietin receptorQ41495072
IL-4 activates a distinct signal transduction cascade from IL-3 in factor-dependent myeloid cellsQ41542996
Interleukin-4 (IL-4) induces protein tyrosine phosphorylation of the IL-4 receptor and association of phosphatidylinositol 3-kinase to the IL-4 receptor in a mouse T cell line, HT2.Q41546868
Phosphatidylinositol 3-kinase associates, via its Src homology 2 domains, with the activated erythropoietin receptor.Q41547736
Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinaseQ41670255
Tyrosine phosphorylation is an obligatory event in IL-2 secretionQ41720987
Role of a pertussis toxin substrate in the control of lectin-induced cap formation in human neutrophilsQ41813927
Regulation of phosphatidylinositol 3'-kinase by tyrosyl phosphoproteins. Full activation requires occupancy of both SH2 domains in the 85-kDa regulatory subunitQ42066856
Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S.Q42479527
Activation of protein-tyrosine kinase p72syk with concanavalin A in polymorphonuclear neutrophils.Q42502268
Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophilsQ43573690
Identification of distinct populations of PI-3 kinase activity following T-cell activation.Q43962492
A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosolQ48104952
Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylationQ67841197
The Lectin Concanavalin A Stimulates a Protein-Tyrosine Kinase p72syk in Peripheral Blood LymphocytesQ72087861
Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinaseQ72237914
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmanninQ72237918
Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activationQ72465669
Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinasesQ72645591
CD28 signal transduction: tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activityQ72797913
P407language of work or nameEnglishQ1860
P304page(s)505-512
P577publication date1996-04-01
P1433published inBiochemical JournalQ864221
P1476titleActivation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human mo
P478volume315 ( Pt 2)

Reverse relations

cites work (P2860)
Q34548314Chemokine signalling: pivoting around multiple phosphoinositide 3-kinases
Q47713299Chemokines and T lymphocytes: more than an attraction
Q42991198Chemokines: understanding their role in T-lymphocyte biology.
Q35048809Development and characterisation of tetracycline-regulated phosphoinositide 3-kinase mutants: assessing the role of multiple phosphoinositide 3-kinases in chemokine signaling.
Q46571032Effect of concanavalin A (Con-A) on the hormone production of the unicellular Tetrahymena and the immune cells of the rat. A comparative study
Q42159024Enhancement of chemotactic peptide-induced activation of phosphoinositide 3-kinase by granulocyte-macrophage colony-stimulating factor and its relation to the cytokine-mediated priming of neutrophil superoxide-anion production
Q43698049Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase
Q31997694Induction of apoptosis and tyrosine phosphorylation of cellular proteins in T cells and non-T cells by stimulation with concanavalin A.
Q73265708Insulin increased cAMP phosphodiesterase activity antagonizing metabolic actions of glucagon in rat hepatocytes cultured with herbimycin A
Q46163274Interferon-gamma activation of a mitogen-activated protein kinase, KFR1, in the bloodstream form of Trypanosoma brucei
Q42444083Negative regulation of class IA phosphoinositide 3-kinase by protein kinase Cdelta Limits Fcgamma receptor-mediated phagocytosis in macrophages
Q33503577Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets.
Q35559953Regulation of IFN-gamma signaling is essential for the cytotoxic activity of CD8(+) T cells
Q41007013The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.
Q34307796The respiratory burst response of surface-adhering leukocytes. A key to tissue engineering
Q39503390Transcription profiles of LPS-stimulated THP-1 monocytes and macrophages: a tool to study inflammation modulating effects of food-derived compounds
Q28252099Tyrosine phosphorylation and relocation of SHIP are integrin-mediated in thrombin-stimulated human blood platelets
Q41116569c-Ras is required for the activation of the matrix metalloproteinases by concanavalin A in 3Y1 cells

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