Glargine and degludec: Solution behaviour of higher dose synthetic insulins.

scientific article published on 4 August 2017

Glargine and degludec: Solution behaviour of higher dose synthetic insulins. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41598-017-06642-W
P932PMC publication ID5544765
P698PubMed publication ID28779138

P50authorStephen E. HardingQ7609121
Paul S. MorganQ51692894
Gary G AdamsQ56855577
Richard B GillisQ56855578
Naomi ChayenQ61994023
Andrew MealQ125292957
P2093author name stringFrank Coffey
Qushmua Alzahrani
Arthur J Rowe
Samil Kok
Shahwar I Jiwani
P2860cites workLigand-controlled assembly of hexamers, dihexamers, and linear multihexamer structures by the engineered acylated insulin degludecQ27683621
Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation ModelingQ27860847
Disulfide Linkage Characterization of Disulfide Bond-Containing Proteins and Peptides by Reducing Electrochemistry and Mass Spectrometry.Q30382778
Evaluation of the information content of sedimentation equilibrium data in self-interacting systemsQ33622585
COVOL: an interactive program for evaluating second virial coefficients from the triaxial shape or dimensions of rigid macromolecules.Q34170398
Insulin degludec in type 1 diabetes: a randomized controlled trial of a new-generation ultra-long-acting insulin compared with insulin glargine.Q34583341
Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long)Q36426912
A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetesQ36449523
Defective counterregulation and hypoglycemia unawareness in diabetes: mechanisms and emerging treatmentsQ36597980
Novel insulin analogues and its mitogenic potentialQ36616563
Insulin glargine and receptor-mediated signalling: clinical implications in treating type 2 diabetesQ36964626
MultiSig: a new high-precision approach to the analysis of complex biomolecular systemsQ37300072
Basal insulin analogues in the management of diabetes mellitus: What progress have we made?Q38136581
The osmotic second virial coefficient for protein self-interaction: Use and misuse to describe thermodynamic nonidealityQ38582064
Proliferative and signaling activities of insulin analogues in endometrial cancer cellsQ38908011
Rational steering of insulin binding specificity by intra-chain chemical crosslinkingQ41960756
The concentration-dependence of macromolecular parametersQ41971526
Equivalent radii and ratios of radii from solution properties as indicators of macromolecular conformation, shape, and flexibility.Q44004609
Comparison of insulin aspart and lispro: pharmacokinetic and metabolic effectsQ44495234
The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patientsQ44631767
Rhombohedral insulin crystal transformationQ45206559
Contrasting weight changes with LY2605541, a novel long-acting insulin, and insulin glargine despite similar improved glycaemic control in T1DM and T2DM.Q47175820
Calculating sedimentation coefficient distributions by direct modeling of sedimentation velocity concentration profilesQ47772554
Concentration dependence of translational diffusion coefficients for globular proteins.Q51026292
Insulin analogues display atypical differentiative activities in skin keratinocytes.Q53535262
Structure of Rhombohedral 2 Zinc Insulin CrystalsQ55872723
Equilibrium cluster formation in concentrated protein solutions and colloidsQ59063283
Structural relationships in the two-zinc insulin hexamerQ66921732
Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical useQ73922459
Long-acting insulin analogues versus NPH human insulin in type 2 diabetes: a meta-analysisQ81317578
Ultra-long-acting insulin degludec has a flat and stable glucose-lowering effect in type 2 diabetesQ84440683
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)7287
P577publication date2017-08-04
P1433published inScientific ReportsQ2261792
P1476titleGlargine and degludec: Solution behaviour of higher dose synthetic insulins
P478volume7

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cites work (P2860)
Q52337945Characterisation of insulin analogues therapeutically available to patients.
Q89681954Clinically Relevant Insulin Degludec and its Interaction with Polysaccharides: A Biophysical Examination