Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain

scientific article

Thermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI7006383
P8608Fatcat IDrelease_muscw3d3cffvddagdvartcbdnq
P932PMC publication ID2111043
P698PubMed publication ID17649979
P5875ResearchGate publication ID6188699

P2093author name stringRichard A Kammerer
Andrei T Alexandrescu
Christine O Sallum
P2860cites workGlobular domains of agrin are functional units that collaborate to induce acetylcholine receptor clusteringQ74620592
Agrin-independent activation of the agrin signal transduction pathwayQ78107668
Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrinQ79165764
Mechanism of interaction of the double-stranded RNA (dsRNA) binding domain of protein kinase R with short dsRNA sequencesQ79468868
Agrin binds to beta-amyloid (Abeta), accelerates abeta fibril formation, and is localized to Abeta deposits in Alzheimer's disease brainQ22253180
Structure of the C-terminal laminin G-like domain pair of the laminin alpha2 chain harbouring binding sites for alpha-dystroglycan and heparinQ24630865
The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrinQ27620848
The laminin-binding domain of agrin is structurally related to N-TIMP-1Q27633688
Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulationQ27639617
Distinct requirements for heparin and alpha-dystroglycan binding revealed by structure-based mutagenesis of the laminin alpha2 LG4-LG5 domain pairQ27641994
Protein production by auto-induction in high density shaking culturesQ27860514
Development of the vertebrate neuromuscular junctionQ28141504
Agrin in the developing CNS: new roles for a synapse organizerQ28203484
Induction, assembly, maturation and maintenance of a postsynaptic apparatusQ28206352
Modulation of agrin function by alternative splicing and Ca2+ bindingQ28249942
Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptorQ28254849
Agrin acts via a MuSK receptor complexQ28280777
Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervationQ28511900
Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSKQ28569020
Agrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchymaQ28645584
Domain structure and organisation in extracellular matrix proteins.Q30329726
Electron microscopic structure of agrin and mapping of its binding site in laminin-1Q33888037
An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.Q34091913
LG/LNS domains: multiple functions -- one business end?Q34282459
Merging extracellular domains: fold prediction for laminin G-like and amino-terminal thrombospondin-like modules based on homology to pentraxinsQ34457974
Glycobiology of the synapseQ34515910
Chemical diversity in the sialic acids and related alpha-keto acids: an evolutionary perspective.Q34527437
Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.Q34699458
New insights into the roles of agrinQ35097331
Glycobiology of neuromuscular disordersQ35123511
Agrin isoforms and their role in synaptogenesisQ35234730
Amyloid accomplices and enforcersQ35970547
Regulation of agrin-induced acetylcholine receptor aggregation by Ca++ and phorbol esterQ36219077
Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lostQ36357189
Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active siteQ36382434
Thermodynamic analysis of the binding of component enzymes in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus.Q38269524
Direct measurement of the interactions of glycosaminoglycans and a heparin decasaccharide with the malaria circumsporozoite proteinQ38296921
Alpha-galactosidase stimulates acetylcholine receptor aggregation in skeletal muscle cells via PNA-binding carbohydratesQ38313144
Interaction of soluble and surface-bound heparin binding growth-associated molecule with heparinQ38322693
Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with lamininQ38349218
The binding surface and affinity of monomeric and dimeric chemokine macrophage inflammatory protein 1 beta for various glycosaminoglycan disaccharidesQ38361416
MuSK glycosylation restrains MuSK activation and acetylcholine receptor clusteringQ38361622
Novel Glycosaminoglycan Precursors as Anti-Amyloid Agents, Part IIIQ40633033
N-acetyllactosamine and the CT carbohydrate antigen mediate agrin-dependent activation of MuSK and acetylcholine receptor clustering in skeletal muscleQ40874394
Alternative splicing of agrin alters its binding to heparin, dystroglycan, and the putative agrin receptorQ41212392
Role for a synapse-specific carbohydrate in agrin-induced clustering of acetylcholine receptorsQ41354044
Binding of amyloid beta-peptide to ganglioside micelles is dependent on histidine-13.Q41816548
Sialic acid inhibits agrin signaling in C2 myotubesQ42485828
Modulation of agrin binding and activity by the CT and related carbohydrate antigensQ43978374
Calcium plays a critical role in determining the acetylcholine receptor-clustering activities of alternatively spliced isoforms of AgrinQ44350710
Sialic acid. A calcium-binding carbohydrateQ44739730
Structural and thermodynamic aspects of the interaction between heparan sulfate and analogues of melittinQ45856340
Mapping sites responsible for interactions of agrin with neuronsQ48450945
Tissue-specific heterogeneity in alpha-dystroglycan sialoglycosylation. Skeletal muscle alpha-dystroglycan is a latent receptor for Vicia villosa agglutinin b4 masked by sialic acid modificationQ48634703
Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques.Q52132803
Alternative RNA splicing that determines agrin activity regulates binding to heparin and alpha-dystroglycanQ71068786
Physiological regulation of the immunological synapse by agrinQ73873116
1H, 13C and 15N backbone assignments for the C-terminal globular domain of agrinQ74418320
P433issue33
P407language of work or nameEnglishQ1860
P304page(s)9541-9550
P577publication date2007-07-25
P1433published inBiochemistryQ764876
P1476titleThermodynamic and structural studies of carbohydrate binding by the agrin-G3 domain
P478volume46