σ Binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture

scientific article published on May 15, 1995

σ Binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0014-2999(95)00115-2
P953full work available at URLhttps://api.elsevier.com/content/article/PII:0014299995001152?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:0014299995001152?httpAccept=text/plain
P698PubMed publication ID7671999

P2093author name stringP. J. Brent
G. T. Pang
P2860cites workNeuropeptide Y and JO 1784, a selective sigma ligand, alter intestinal ion transport through a common, haloperidol-sensitive siteQ67683951
MHC-restricted responses of CD8+ and CD4+ T-cell clones from regional lymph nodes of melanoma patientsQ68100933
An improved synthesis of [125I]N-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanomaQ70632605
Sigma receptor ligands modulate contractility, Ca++ influx and beating rate in cultured cardiac myocytesQ72023104
The sigma compounds 1,3-di-o-tolylguanidine and N-allylnormetazocine inhibit agonist-stimulated inositol phospholipid metabolism in bovine adrenal medullary cellsQ72139610
Sigma receptor-active neuroleptics are cytotoxic to C6 glioma cells in cultureQ72210279
Specific in vitro and in vivo binding of 3H-raclopride. A potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brainQ28235437
A human cell line from a pleural effusion derived from a breast carcinomaQ34207627
Apoptosis: Mechanisms and Roles in PathologyQ36508777
Sigma receptors: biology and functionQ37566475
In vitro and in vivo expression of opioid and sigma receptors in rat C6 glioma and mouse N18TG2 neuroblastoma cellsQ41451140
Binding of opioids to human MCF-7 breast cancer cells and their effects on growthQ41737251
Sigma and opioid receptors in human brain tumorsQ41860587
Calcium-dependent displacement of haloperidol-sensitive sigma receptor binding in rat hippocampal slices following tissue depolarizationQ42189146
Initial identification and characterization of sigma receptors on human peripheral blood leukocytesQ42200844
Correlation of inhibitory potencies of putative antagonists for sigma receptors in brain and spleenQ42202506
Evidence that the potential antipsychotic agent rimcazole (BW 234U) is a specific, competitive antagonist of sigma sites in brainQ42650491
Expression of (+)-3-PPP binding sites in the PC12 pheochromocytoma cell lineQ44309530
Evidence for a non-opioid sigma binding site in the guinea-pig myenteric plexusQ44342956
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranesQ46517809
(+)-[3H]SK&F 10,047 binding sites in rat liverQ48102382
Regional variation in the ratio of sigma 1 to sigma 2 binding in rat brainQ48104179
Competitive interactions at [3H]1,3-di(2-tolyl)guanidine (DTG)-defined sigma recognition sites in guinea pig brainQ48595138
BW 234U, (cis-9-[3-(3,5-dimethyl-1-piperazinyl)propyl]carbazole dihydrochloride): a novel antipsychotic agentQ48942600
A proposal for the classification of sigma binding sitesQ67487993
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcolon carcinomaQ18554829
P304page(s)151-160
P577publication date1995-05-01
1995-05-15
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleSigma binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture
σ Binding site ligands inhibit cell proliferation in mammary and colon carcinoma cell lines and melanoma cells in culture
P478volume278

Reverse relations

cites work (P2860)
Q358127114-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs
Q33575961Acute effects of the sigma-2 receptor agonist siramesine on lysosomal and extra-lysosomal proteolytic systems in lens epithelial cells
Q46213643Altered expression level of Sigma1 receptor gene in human colorectal cancer.
Q24635201Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor
Q34172682Early development of sigma-receptor ligands
Q73017536Effect of haloperidol on the development of the solid Ehrlich tumor in mice
Q42582270Effects of sigma ligands on the cloned mu-, delta- and kappa-opioid receptors co-expressed with G-protein-activated K+ (GIRK) channel in Xenopus oocytes
Q34135447Family of hemorphins: co-relations between amino acid sequences and effects in cell cultures
Q46931420Haloperidol induces apoptosis via the sigma2 receptor system and Bcl-XS.
Q40996612Increased binding to sigma sites of N-[1'(2-piperidinyl)ethyl)-4-[I-125]-iodobenzamide (I-125-PAB) with onset of tumor cell proliferation
Q71820034Inhibition of the expression of ornithine decarboxylase by haloperidol in difluoromethylornithine-resistant leukemia cells
Q39629670Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP)-targeted delivery of soluble TRAIL potently inhibits melanoma outgrowth in vitro and in vivo
Q97069885Novel thymoquinone lipidic core nanocapsules with anisamide-polymethacrylate shell for colon cancer cells overexpressing sigma receptors
Q58572111Overexpression of sigma-1 receptor in MCF-7 cells enhances proliferation via the classic protein kinase C subtype signaling pathway
Q36085625Overexpression of sigma1 receptor and its positive associations with pathologic TNM classification in esophageal squamous cell carcinoma
Q44494959Preclinical acute toxicity studies and rodent-based dosimetry estimates of the novel sigma-1 receptor radiotracer [(18)F]FPS.
Q39082987Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy
Q35673122Review of the pharmacological and clinical profile of rimcazole.
Q34250906S2R(Pgrmc1): the cytochrome-related sigma-2 receptor that regulates lipid and drug metabolism and hormone signaling
Q35924939Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy
Q40878476Sigma ligands inhibit the growth of small cell lung cancer cells
Q37000551Sigma receptors [σRs]: biology in normal and diseased states
Q34362333Sigma-2 receptor ligands and their perspectives in cancer diagnosis and therapy.
Q39458668Sigma1 Pharmacology in the Context of Cancer
Q40913236Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor
Q36590723Synthesis and characterization of N,N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors
Q48311125Synthesis and evaluation of 11C- and 18F-labeled 1-[2-(4-alkoxy-3-methoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazines as sigma receptor ligands for positron emission tomography studies
Q47860855Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.
Q35148443Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors.
Q36900115The cell death response to gamma-radiation in MCF-7 cells is enhanced by a neuroleptic drug, pimozide
Q38123807The sigma-1 receptor: a regulator of cancer cell electrical plasticity?

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