Synapsin I, a phosphoprotein associated with synaptic vesicles: possible role in regulation of neurotransmitter release

scientific article published on January 1987

Synapsin I, a phosphoprotein associated with synaptic vesicles: possible role in regulation of neurotransmitter release is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/978-1-4684-7618-7_11
P698PubMed publication ID2893522

P50authorPaul GreengardQ309979
P2093author name stringM D Browning
R Llinas
T L McGuinness
P2860cites workDirect phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activationQ24616223
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparationQ24681205
Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by immunofluorescence in frozen and plastic sectionsQ24681224
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1Q28259380
The role of protein phosphorylation in neural and hormonal control of cellular activityQ28264521
Phosphorylation-Dephosphorylation of EnzymesQ28306047
A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regionsQ28643908
Widespread distribution of protein I in the central and peripheral nervous systemsQ33983553
Presynaptic calcium currents in squid giant synapse.Q34251993
Stimulation of brain membrane protein phosphorylation by calcium and an endogenous heat-stable proteinQ34253460
A calcium/calmodulin-dependent protein kinase from mammalian brain that phosphorylates Synapsin I: partial purification and characterization.Q34259133
Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptorQ34708390
Two calcium/calmodulin-dependent protein kinases, which are highly concentrated in brain, phosphorylate protein I at distinct sitesQ35429183
Depolarizing agents and cyclic nucleotides regulate the phosphorylation of specific neuronal proteins in rat cerebral cortex slicesQ35996834
Synapsin I (Protein I), a nerve terminal-specific phosphoprotein. II. Its specific association with synaptic vesicles demonstrated by immunocytochemistry in agarose-embedded synaptosomesQ36208140
Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylationQ36262245
Cellular and subcellular localization of protein I in the peripheral nervous systemQ36292951
Intracellular injection of protein kinase inhibitor blocks the serotonin-induced increase in K+ conductance in Aplysia neuron R15.Q36300530
Ca2+ -activated K+ conductance in internally perfused snail neurons is enhanced by protein phosphorylationQ36302977
Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomesQ36310039
Regulation of phosphorylation of proteins I, IIIa, and IIIb in rat neurohypophysis in vitro by electrical stimulation and by neuroactive agentsQ36314990
Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglionQ36420230
Microinjection of catalytic subunit of cyclic AMP-dependent protein kinase enhances calcium action potentials of bag cell neurons in cell cultureQ36420298
Intracellular injection of t he catalytic subunit of cyclic AMP-dependent protein kinase simulates facilitation of transmitter release underlying behavioral sensitization in AplysiaQ36420332
Phosphorylation of liver histone following the administration of glucagon and insulinQ36442708
Immunocytochemical localization of calcium/calmodulin-dependent protein kinase II in rat brainQ37567101
Phosphorylation of the nicotinic acetylcholine receptor by an endogenous tyrosine-specific protein kinaseQ37576731
Ca2+-dependent protein phosphorylation system in membranes from various tissues, and its activation by "calcium-dependent regulator"Q37594175
Phosphorylation induces a decrease in the biological activity of the protein inhibitor (GABA-modulin) of gamma-aminobutyric acid binding sitesQ37603489
Evidence for widespread effects of noradrenaline on axon terminals in the rat frontal cortexQ37677401
Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapseQ37687077
Protein phosphorylation and neuronal functionQ38395292
Calsequestrin, Myosin, and the Components of the Protein-Glycogen Complex in Rabbit Skeletal MuscleQ39599932
Evidence for protein phosphorylation and dephosphorylation in membrane fragments isolated from the electric organ ofElectrophorus electricusQ40048809
An endogenous substrate for cGMP-dependent protein kinase in mammalian cerebellumQ40173180
Neuronal localization of specific brain phosphoproteinsQ40182611
Synaptic Phosphoproteins: Specific Changes After Repetitive Stimulation of the Hippocampal SliceQ40192686
Neural tissues express high levels of the cellular src gene product pp60c-srcQ40674207
Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ currentQ41553666
Regulation of the Muscarinic Acetylcholine Receptor: Effects of Phosphorylating Conditions on Agonist and Antagonist BindingQ42246035
Insulin trigger, cyclic AMP-dependent activation and phosphorylation of a plasma membrane cyclic AMP phosphodiesteraseQ42450891
D-1 and D-2 dopaminergic receptors regulate protein phosphorylation in the rat neurohypophysisQ45145256
ACTH, cyclic nucleotides, and brain protein phosphorylation in vitroQ47712853
Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C.Q48534850
Synapsin I in nerve terminals: selective association with small synaptic vesiclesQ48590970
Cross-Reaction of Anti-Rat B-50: Characterization and Isolation of a "B-50 Phosphoprotein" from Bovine BrainQ48619260
Phosphorylation of the alpha subunit of the sodium channel by protein kinase C.Q48631410
Long-term potentiation in the hippocampal slice: possible involvement of pyruvate dehydrogenaseQ48658155
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleusQ48691482
A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinaseQ48715327
Isolation of brain Ca2+-calmodulin tubulin kinase containing calmodulin binding proteinsQ48896642
Evidence that high frequency stimulation influences the phosphorylation of pyruvate dehydrogenase and that the activity of this enzyme is linked to mitochondrial calcium sequestrationQ49030105
Ribosomal protein phosphorylation and protein synthesis in the brainQ49030148
Activation of multiple S6 phosphorylation and its possible role in the alteration of mRNA expressionQ49030170
ACTH and synaptic membrane phosphorylation in rat brainQ49102441
Protein phosphorylation in the regulation and adaptation of receptor functionQ49102514
Neurotransmitter- and neuromodulator-dependent alterations in phosphorylation of protein I in slices of rat facial nucleus.Q53982406
Protein Kinase Injection Reduces Voltage-Dependent Potassium CurrentsQ54503145
Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglionQ59096972
Phosphorylation of acetylcholine receptor by endogenous membrane protein kinase in receptor-enriched membranes of Torpedo californicaQ67589514
Serotonin stimulates phosphorylation of protein I in the facial motor nucleus of rat brainQ71530231
Tyrosine 3-monooxygenase is phosphorylated by Ca2+-, calmodulin-dependent protein kinase, followed by activation by activator proteinQ72491772
Evidence for phosphorylation of rat brain guanylate cyclase by cyclic AMP-dependent protein kinaseQ72508228
Attachment of the synapse-specific phosphoprotein protein I to the synaptic membrane: a possible role of the collagenase-sensitive region of protein IQ72879640
Possible nuclear protein kinase regulation of homologous ribonucleic acid polymerases from small dense nuclei of mouse brain during morphine tolerance-dependence. Involvement of cyclic 3',5'-adenosine monophosphateQ72910878
Protein kinases of retinal rod outer segments: identification and partial characterization of cyclic nucleotide dependent protein kinase and rhodopsin kinaseQ72919820
Calcium in synaptic transmissionQ72961954
A technique for recording functional activity in specific groups of medullated and non-medullated fibres in whole nerve trunksQ74613068
The Functioning of the Giant Nerve Fibres of the SquidQ113342531
P407language of work or nameEnglishQ1860
P921main subjectneurotransmitterQ162657
P304page(s)135-153
P577publication date1987-01-01
P1433published inAdvances in Experimental Medicine and BiologyQ4686385
P1476titleSynapsin I, a phosphoprotein associated with synaptic vesicles: possible role in regulation of neurotransmitter release
P478volume221

Reverse relations

cites work (P2860)
Q33860321Effects of synapsin I and calcium/calmodulin-dependent protein kinase II on spontaneous neurotransmitter release in the squid giant synapse
Q48596618Isoproterenol increases the phosphorylation of the synapsins and increases synaptic transmission in dentate gyrus, but not in area CA1, of the hippocampus
Q34749299Mover is a homomeric phospho-protein present on synaptic vesicles
Q52451303Regulation by synapsin I and Ca(2+)-calmodulin-dependent protein kinase II of the transmitter release in squid giant synapse.
Q35800404Regulation of CNS synapses by neuronal MHC class I.
Q37914375Synapsin III: role in neuronal plasticity and disease
Q48726387Synapsin dispersion and reclustering during synaptic activity