Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial

scientific article published on 19 June 2017

Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial is …
instance of (P31):
scholarly articleQ13442814

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P5530Altmetric DOI10.1016/S1470-2045(17)30318-2
P6409CORE ID153791437
P6179Dimensions Publication ID1086085229
P356DOI10.1016/S1470-2045(17)30318-2
P953full work available at URLhttp://eprints.whiterose.ac.uk/117960/
P932PMC publication ID5555437
P698PubMed publication ID28642008
P1154Scopus EID2-s2.0-85020944773

P50authorPierre FournelQ56424312
Jason PantarottoQ56424313
Penella WollQ57474508
Jan Van MeerbeeckQ91985767
Paul LoriganQ32649737
Corinne Faivre-FinnQ37830473
Fiona BlackhallQ37831554
P2093author name stringFelipe Cardenal
Andrea Bezjak
Jan P Van Meerbeeck
Linda Ashcroft
Mary O'Brien
Fabrice Barlesi
Michael Snee
Cecile Le Pechoux
Rhona McMenemin
Veerle Surmont
Susan Harden
Nazia Mohammed
Adityanarayan Bhatnagar
CONVERT Study Team
Wiebke Appel
P2860cites workChanging epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database.Q50789972
The IASLC Lung Cancer Staging Project: proposals regarding the relevance of TNM in the pathologic staging of small cell lung cancer in the forthcoming (seventh) edition of the TNM classification for lung cancer.Q53189764
Time Between the First Day of Chemotherapy and the Last Day of Chest Radiation Is the Most Important Predictor of Survival in Limited-Disease Small-Cell Lung CancerQ57618367
Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposideQ77912158
Early versus late chest radiotherapy in patients with limited-stage small cell lung cancerQ24245945
Toxicity and response criteria of the Eastern Cooperative Oncology GroupQ29619399
Impact of thoracic radiotherapy timing in limited-stage small-cell lung cancer: usefulness of the individual patient data meta-analysisQ30248898
Phase I study to determine the maximum-tolerated dose of radiation in standard daily and hyperfractionated-accelerated twice-daily radiation schedules with concurrent chemotherapy for limited-stage small-cell lung cancerQ33504330
Keynote address on biostatistics and data retrieval.Q34213509
Do age and comorbidity impact treatment allocation and outcomes in limited stage small-cell lung cancer? a community-based population analysisQ35091203
A meta-analysis of the timing of chest irradiation in the combined modality treatment of limited-stage small cell lung cancerQ35961932
Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancerQ35966667
Systematic review and meta-analysis of randomised, controlled trials of the timing of chest radiotherapy in patients with limited-stage, small-cell lung cancerQ36339439
Protocol for the CONVERT trial-Concurrent ONce-daily VErsus twice-daily RadioTherapy: an international 2-arm randomised controlled trial of concurrent chemoradiotherapy comparing twice-daily and once-daily radiotherapy schedules in patients with limQ36526895
Penetration of recommended procedures for lung cancer staging and management in the United States over 10 years: a quality research in radiation oncology surveyQ37498889
A meta-analysis of thoracic radiotherapy for small-cell lung cancerQ41086687
Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-analysisQ45371243
Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. The National Cancer Institute of Canada Clinical Trials GroupQ48341719
Treatment of small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.Q48477176
Patients with limited-stage small-cell lung cancer treated with concurrent twice-daily chest radiotherapy and etoposide/cisplatin followed by cyclophosphamide, doxorubicin, and vincristineQ49102895
P433issue8
P921main subjectchemoradiotherapyQ5090613
phase III clinical trialQ42824827
P304page(s)1116-1125
P577publication date2017-06-19
P1433published inLancet Oncology CommissionQ13747613
P1476titleConcurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial
P478volume18

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cites work (P2860)
Q9001642018F-Fludeoxyglucose PET/CT in SCLC: Analysis of the CONVERT Randomized Controlled Trial
Q92862797A Meta-Analysis of the Efficacy and Toxicity of Twice-Daily vs. Once-Daily Concurrent Chemoradiotherapy for Limited-Stage Small Cell Lung Cancer Based on Randomized Controlled Trials
Q57806334A pooled analysis of individual patient data from National Clinical Trials Network clinical trials of concurrent chemoradiotherapy for limited-stage small cell lung cancer in elderly patients versus younger patients
Q62851605Association of Chemoradiotherapy With Outcomes Among Patients With Stage I to II vs Stage III Small Cell Lung Cancer: Secondary Analysis of a Randomized Clinical Trial.
Q92111378Association of Twice-Daily Radiotherapy With Subsequent Brain Metastases in Adults With Small Cell Lung Cancer
Q93334895Bracing for impact with new 4R's in the COVID-19 pandemic- a provincial thoracic radiation oncology consensus
Q50060045CONVERTed or not: what are the barriers to implementing the evidence?
Q50060039CONVERTed or not: what are the barriers to implementing the evidence? - Author's reply
Q91844914Clinical outcomes and toxicity predictors of thoracic re-irradiation for locoregionally recurrent lung cancer
Q52587549Comparing Treatment Strategies for Stage I Small-cell lung Cancer.
Q55516294Comparison and discussion of the treatment guidelines for small cell lung cancer.
Q58574211Compliance and outcome of elderly patients treated in the Concurrent ONce daily VErsus twice-daily RadioTherapy (CONVERT) trial
Q49978476Concurrent once-daily or twice-daily chemoradiotherapy in limited-stage small-cell lung cancer?
Q98226197Current Management and Progress in Radiotherapy for Small Cell Lung Cancer
Q47989130Current Treatments for Surgically Resectable, Limited-Stage, and Extensive-Stage Small Cell Lung Cancer
Q54953051Current standards for clinical management of small cell lung cancer.
Q91243409Final report of a prospective randomized study on thoracic radiotherapy target volume for limited-stage small cell lung cancer with radiation dosimetric analyses
Q92356134Heart V5 predicts cardiac events in unresectable lung cancer patients undergoing chemoradiation
Q92236896Immune checkpoint inhibitors for small cell lung cancer: opportunities and challenges
Q55093161Impact of radiation dose on concurrent chemoradiotherapy for limited-stage small-cell lung cancer.
Q91724678Initial management of small-cell lung cancer (limited- and extensive-stage) and the role of thoracic radiotherapy and first-line chemotherapy: a systematic review
Q57785727Interim Analysis of a Two-Institution, Prospective Clinical Trial of 4DCT-Ventilation-based Functional Avoidance Radiation Therapy
Q95405638Is it time to convert the frequency of radiotherapy in small-cell lung cancer?
Q50261220Is it time to convert the frequency of radiotherapy in small-cell lung cancer?
Q89129779Is it time to convert the frequency of radiotherapy in small-cell lung cancer?
Q50261212Is it time to convert the frequency of radiotherapy in small-cell lung cancer? - Authors' reply
Q99603504Neutrophil-to-lymphocyte ratio can predict outcome in extensive-stage small cell lung cancer
Q55062496No room for statins in the quest for survival benefits in small cell lung cancer.
Q60926671Outcomes of re-irradiation for brain recurrence after prophylactic or therapeutic whole-brain irradiation for small cell lung Cancer: a retrospective analysis
Q91742354Patterns of care and survival outcomes for laryngeal small cell cancer
Q89947460Phase II Study of Consolidation Amrubicin After Concurrent Chemoradiotherapy in Patients With Limited-stage Small-cell Lung Cancer
Q56528378Practice-changing radiation therapy trials for the treatment of cancer: where are we 150 years after the birth of Marie Curie?
Q55079973Preexisting radiological interstitial lung abnormalities are a risk factor for severe radiation pneumonitis in patients with small-cell lung cancer after thoracic radiation therapy.
Q90290807Prognostic value of circulating tumour cells in limited-stage small-cell lung cancer: analysis of the concurrent once-daily versus twice-daily radiotherapy (CONVERT) randomised controlled trial
Q55358944Proton therapy for small cell lung cancer.
Q50139034Radiation Dose to the Thoracic Vertebral Bodies Is Associated With Acute Hematologic Toxicities in Patients Receiving Concurrent Chemoradiation for Lung Cancer: Results of a Single-Center Retrospective Analysis
Q55038620Radiation Oncology in the 21st Century: Prospective Randomized Trials That Changed Practice… or Didn't!
Q94592974Radiotherapy in Lung Cancer: Current and Future Role
Q98467055Radiotherapy target volume for limited-disease small cell lung cancer: good news from the dark side of the moon
Q94672120Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic
Q47115640Research in imaging/biomarkers for precision medicine in lung cancer: National Cancer Institute funding opportunities
Q89630996SEOM clinical guidelines for the treatment of small-cell lung cancer (SCLC) (2019)
Q91638654Sequential chemotherapy followed by radical thoracic radiotherapy (50 Gy in 25 fractions) in limited stage small cell lung cancer
Q92072927Significance of overall concurrent chemoradiotherapy duration on survival outcomes of stage IIIB/C non-small-cell lung carcinoma patients: Analysis of 956 patients
Q55023905Sites of recurrent disease and prognostic factors in SCLC patients treated with radiochemotherapy.
Q64084792Spatially Specific Liposomal Cancer Therapy Triggered by Clinical External Sources of Energy
Q49207460Surgery for small cell lung cancer in the modern era: opportunities and challenges
Q49886142The Role of Advanced Imaging in Assessing Response to Definitive Chemoradiation Before Prophylactic Cranial Irradiation in Limited-Stage Small-Cell Lung Cancer.
Q41605002The clinical utility of circulating tumour cells in patients with small cell lung cancer
Q52672760The effect of post-progression survival on overall survival among patients with sensitive relapse of small cell lung cancer.
Q58804836The evolving role of radiotherapy in the management of small cell lung cancer
Q61804643The optimal treatment approaches for stage I small cell lung cancer
Q92136222Thoracic radiation therapy during COVID-19: provisional guidelines from a comprehensive cancer center within a pandemic epicenter
Q95295671Treatment guidance for lung cancer patients during the COVID-19 pandemic
Q92382555Treatment time to the end of thoracic radiotherapy has more predictive power for survival than radiation dose intensity in patients with limited-stage small-cell lung cancer receiving concurrent chemoradiation of more than 45 Gy
Q47153324Twice-daily chemoradiotherapy must still be the choice for patients with limited-stage small-cell lung cancer
Q53705076Which fractionation of radiotherapy is best for limited-stage small-cell lung cancer?
Q91326771Will liquid biopsies improve outcomes for patients with small-cell lung cancer?

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