Development of CD4-CD8+ cytotoxic T cells requires interactions with class I MHC determinants

scientific article published on May 1988

Development of CD4-CD8+ cytotoxic T cells requires interactions with class I MHC determinants is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1021211484
P356DOI10.1038/333180A0
P698PubMed publication ID3259290

P50authorDan LongoQ12100062
P2093author name stringKruisbeek AM
Stephany DA
Maruŝić-Galesić S
P2860cites workOn the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?Q36340069
H-2 antigens of the thymus determinelymphocyte specificityQ36341908
Cytotoxic T lymphocyte responses by chimeric thymocytes. Self-recognition is determined early in T cell developmentQ36344396
Cytotoxic T lymphocyte responses in allogeneic radiation bone marrow chimeras. The chimeric host strictly dictates the self-repertoire of Ia-restricted T cells but not H-2K/D-restricted T cellsQ36347155
Early development of the T cell repertoire. In vivo treatment of neonatal mice with anti-Ia antibodies interferes with differentiation of I-restricted T cells but not K/D-restricted T cellsQ36347912
Self-recognition specificity expressed by T cells from nude mice. Absence of detectable Ia-restricted T cells in nude mice that do exhibit self-K/D-restricted T cell responsesQ36349124
Thymus dictates major histocompatibility complex (MHC) specificity and immune response gene phenotype of class II MHC-restricted T cells but not of class I MHC-restricted T cellsQ36349635
Absence of the Lyt-2-,L3T4+ lineage of T cells in mice treated neonatally with anti-I-A correlates with absence of intrathymic I-A-bearing antigen-presenting cell functionQ36349965
Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cellsQ36350774
Monoclonal antibodies to mouse major histocompatibility complex antigens.Q36649460
The role of the T-cell receptor in thymocyte maturation: effects in vivo of anti-receptor antibodyQ37407953
Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen-ReactivityQ40108126
T Cell Subsets and the Recognition of MHC ClassQ40115713
Cytotoxic T cells learn specificity for self H–2 during differentiation in the thymusQ40666806
T cell tolerance by clonal elimination in the thymusQ56922465
Characterization of murine thymocytes with CDS-associated T-cell receptor structuresQ59094024
P433issue6169
P407language of work or nameEnglishQ1860
P304page(s)180-183
P577publication date1988-05-01
P1433published inNatureQ180445
P1476titleDevelopment of CD4-CD8+ cytotoxic T cells requires interactions with class I MHC determinants
P478volume333

Reverse relations

cites work (P2860)
Q41734593A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2.
Q24336028A mutation in zap-70 protein tyrosine kinase results in a selective immunodeficiency
Q68046975A unified model for T cell antigen recognition and thymic selection of the T cell repertoire
Q43416478Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.
Q41658115Analysis of the peripheral T-cell compartment in the MHC class II deficiency syndrome
Q56888991Antibodies against the T cell receptor/CD3 complex interfere with distinct intra-thymic cell-cell interactionsin vivo: correlation with arrest of T cell differentiation
Q52483263Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.
Q67902646Bone marrow-derived progenitor T cells convey the origin of maturational arrest from CD4+CD8+ to CD4−CD8+ thymocytes in LEC mutant rats
Q35769448CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision
Q36350462CD8 is required during positive selection of CD4-/CD8+ T cells
Q36231770Distinctive selection mechanisms govern the T cell receptor repertoire of peripheral CD4-CD8- alpha/beta T cells
Q67275631Effect of interferon-gamma and tumor necrosis factor-alpha on lymphoepithelial interactions within thymic nurse cells
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Q44386503Increased number of cytotoxic T cells within CD4+8- T cells in beta 2-microglobulin, major histocompatibility complex class I-deficient mice
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Q47911167Molecular and cellular events in early thymocyte development
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Q44276459Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the alpha 3 domain of MHC I molecules
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Q52244580Positive selection of CD4+ T cells mediated by MHC class II-bearing stromal cell in the thymic cortex.
Q58993577Positive selection of CD4-CD8+ T cells in the thymus of normal mice
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