Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice

scientific article published on 28 September 2015

Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/DDDT.S89096
P8608Fatcat IDrelease_as7mk6moojcr3cdomdo7gzm2oe
P932PMC publication ID4592035
P698PubMed publication ID26451091

P50authorChuanyong GuoQ79614860
Yu-Qing MaoQ85888858
P2093author name stringFujun Yu
Jianbo Wang
Xiaoming Fan
Jian Cheng
Huanqing Li
P2860cites workBax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaQ22008484
Ghrelin is a growth-hormone-releasing acylated peptide from stomachQ22010951
Anti-apoptotic BCL-2 family proteins in acute neural injuryQ26862539
Autophagy in health and disease: a double-edged swordQ29618103
Opposite effects of high and low doses of interleukin-2 on T cell-mediated hepatitis in mice (interleukin-2 on hepatitis)Q34130411
Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis.Q34201761
Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human diseaseQ34306431
The protective effect of intrasplenic transplantation of Ad-IL-18BP/IL-4 gene-modified fetal hepatocytes on ConA-induced hepatitis in miceQ34630072
Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesityQ34635506
A T cell-dependent experimental liver injury in mice inducible by concanavalin AQ35603939
Importance of Kupffer cells for T-cell-dependent liver injury in miceQ35829575
Mitochondrial control of nuclear apoptosis.Q36366491
Fenofibrate pre-treatment suppressed inflammation by activating phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) signaling in renal ischemia-reperfusion injury.Q54174524
Immunological aspects and therapeutic significance of an autoantibody against histone H1 in a rat model of concanavalin A-induced hepatitis.Q54696471
Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin AQ71215744
Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in miceQ74477596
Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapyQ36736714
Autophagy in the liverQ37130393
Ethyl pyruvate ameliorates hepatic ischemia-reperfusion injury by inhibiting intrinsic pathway of apoptosis and autophagyQ37455325
CD4 T cells in hepatic immune toleranceQ37589899
Prediction of risk for hepatocellular carcinoma by response of serum α-fetoprotein to entecavir therapy.Q39036183
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivoQ40384702
Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitisQ42157047
Changes of PI3K/AKT/BCL2 signaling proteins in congenital Giant Nevi: melanocytes contribute to their increased survival and integrity.Q42620190
Dexmedetomidine premedication attenuates concanavalin A-induced hepatitis in miceQ42704109
Ghrelin inhibits the apoptosis of MC3T3-E1 cells through ERK and AKT signaling pathwayQ42710000
Ghrelin inhibits apoptosis induced by palmitate in rat aortic endothelial cells.Q42789594
Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humansQ43193400
Administration of ghrelin improves inflammation, oxidative stress, and apoptosis during and after non-alcoholic fatty liver disease developmentQ43995966
Ghrelin in chronic liver diseaseQ44381036
Ghrelin induces proliferation in human aortic endothelial cells via ERK1/2 and PI3K/Akt activationQ46448916
Ghrelin alleviates early brain injury after subarachnoid hemorrhage via the PI3K/Akt signaling pathway.Q48558042
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)5385-5396
P577publication date2015-09-28
P1433published inDrug Design, Development and TherapyQ2566724
P1476titleGhrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice
P478volume9

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cites work (P2860)
Q64077081A C21-Steroidal Glycoside from Cynanchum atratum Attenuates Concanavalin A-Induced Liver Injury in Mice
Q44449819Anti-inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation.
Q51496124Effects of kinsenoside, a potential immunosuppressive drug for autoimmune hepatitis, on dendritic cells/CD8+ T cells communication in mice.
Q36598500Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3.
Q64980071Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity.
Q52592942Pristimerin as a Novel Hepatoprotective Agent Against Experimental Autoimmune Hepatitis.
Q38547464Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Q41517897Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.
Q54978043Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Q61455810The Protective Effect of Sheep Placental Extract on Concanavalin A-induced Liver Injury in Mice
Q37713018The protective effects of shikonin on hepatic ischemia/reperfusion injury are mediated by the activation of the PI3K/Akt pathway.

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