A comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: upregulation of IL-1α in highly pathogenic strain induced lesions

scientific article published on 12 February 2015

A comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: upregulation of IL-1α in highly pathogenic strain induced lesions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VETIMM.2015.02.003
P698PubMed publication ID25739319
P5875ResearchGate publication ID273150148

P50authorJaime Gómez-LagunaQ47504083
José María Caridad Y OcerínQ74146531
Simon P. GrahamQ40074007
Francisco J. SalgueroQ40256272
Jean-Pierre FrossardQ45358627
P2093author name stringTrevor W Drew
Sophie B Morgan
Librado Carrasco
Irene M Rodríguez-Gómez
Shyrley P Amarilla
P2860cites workCytokine expression by macrophages in the lung of pigs infected with the porcine reproductive and respiratory syndrome virusQ45382031
Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs.Q45416506
Pathogenic and humoral immune responses to porcine reproductive and respiratory syndrome virus (PRRSV) are related to viral load in acute infectionQ45559476
Expression of interferon-alpha and Mx1 protein in pigs acutely infected with porcine reproductive and respiratory syndrome virus (PRRSV).Q45657842
Expression of interleukin-10 and interleukin-12 in piglets experimentally infected with porcine reproductive and respiratory syndrome virus (PRRSV).Q45722199
Immunohistochemical staining of IFN-gamma positive cells in porcine reproductive and respiratory syndrome virus-infected lungsQ45729659
Expression of Interferon-gamma and tumour necrosis factor-alpha in pigs experimentally infected with Porcine Reproductive and Respiratory Syndrome Virus (PRRSV).Q45730651
Temporal and morphologic characterization of the distribution of porcine reproductive and respiratory syndrome virus (PRRSV) by in situ hybridization in pigs infected with isolates of PRRSV that differ in virulenceQ45763069
Comparative pathogenicity of nine US porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrum-deprived pig modelQ45764832
Porcine reproductive and respiratory syndrome virus vaccines: Immunogenicity, efficacy and safety aspectsQ26825847
Pathogenesis and antigenic characterization of a new East European subtype 3 porcine reproductive and respiratory syndrome virus isolateQ33595227
Proinflammatory cytokines and viral respiratory disease in pigsQ33898122
Dynamic changes in inflammatory cytokines in pigs infected with highly pathogenic porcine reproductive and respiratory syndrome virusQ34150399
Cytokine profiles and phenotype regulation of antigen presenting cells by genotype-I porcine reproductive and respiratory syndrome virus isolatesQ34569610
In vivo studies on cytokine involvement during acute viral respiratory disease of swine: troublesome but rewardingQ34693331
Pathogenic characteristics of three genotype II porcine reproductive and respiratory syndrome viruses isolated from ChinaQ36741372
Cytokine production and signaling pathways in respiratory virus infectionQ37176690
Immunopathogenesis of porcine reproductive and respiratory syndrome in the respiratory tract of pigs.Q38069683
Arterivirus molecular biology and pathogenesisQ38128538
Impact of PRRSV on activation and viability of antigen presenting cells.Q38167021
Differences in clinical disease and immune response of pigs challenged with a high-dose versus low-dose inoculum of porcine reproductive and respiratory syndrome virusQ39940498
Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulenceQ40272313
Proinflammatory cytokines induce lymphocyte apoptosis in acute African swine fever infection.Q40508524
Upregulation of IL-10 gene expression in porcine peripheral blood mononuclear cells by porcine reproductive and respiratory syndrome virusQ40566308
Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virusQ40678125
Pathology and Virus Distribution in the Lung and Lymphoid Tissues of Pigs Experimentally Inoculated with Three Distinct Type 1 PRRS Virus Isolates of Varying PathogenicityQ41670384
Lung pathogenicity of European genotype 3 strain porcine reproductive and respiratory syndrome virus (PRRSV) differs from that of subtype 1 strainsQ41707401
Cytokines transcript levels in lung and lymphoid organs during genotype 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infectionQ42224953
Highly pathogenic porcine reproductive and respiratory syndrome virus infection results in acute lung injury of the infected pigsQ42240516
Chinese and Vietnamese strains of HP-PRRSV cause different pathogenic outcomes in United States high health swineQ42246210
Virulence and genotype-associated infectivity of interferon-treated macrophages by porcine reproductive and respiratory syndrome virusesQ42256176
The genetic diversity of European type PRRSV is similar to that of the North American type but is geographically skewed within EuropeQ42682037
Comparison of the virulence of European and North American genotypes of porcine reproductive and respiratory syndrome virus in experimentally infected pigsQ43534860
Experimental infection of United States swine with a Chinese highly pathogenic strain of porcine reproductive and respiratory syndrome virusQ44051646
Downregulation of antigen-presenting cells in tonsil and lymph nodes of porcine reproductive and respiratory syndrome virus-infected pigs.Q44731039
Comparative pathogenicity of type 1 and type 2 isolates of porcine reproductive and respiratory syndrome virus (PRRSV) in a young pig infection model.Q44919895
Definition of subtypes in the European genotype of porcine reproductive and respiratory syndrome virus: nucleocapsid characteristics and geographical distribution in Europe.Q45223285
Comparative pathogenicity of three Korean and one Lelystad type 1 porcine reproductive and respiratory syndrome virus (pan-European subtype 1) isolates in experimentally infected pigsQ45351315
Increased pathogenicity of European porcine reproductive and respiratory syndrome virus is associated with enhanced adaptive responses and viral clearanceQ45353084
Immunohistochemical expression of IL-12, IL-10, IFN-α and IFN-γ in lymphoid organs of porcine reproductive and respiratory syndrome virus-infected pigsQ45355535
Differential expression of proinflammatory cytokines in the lymphoid organs of porcine reproductive and respiratory syndrome virus-infected pigsQ45364065
Immune responses in piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virusQ45366240
P433issue3-4
P921main subjectexperimental infectionQ107184421
P304page(s)137-147
P577publication date2015-02-12
P1433published inVeterinary Immunology and ImmunopathologyQ7923704
P1476titleA comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: upregulation of IL-1α in highly pathogenic strain induced lesions
P478volume164

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cites work (P2860)
Q96813621Activation of pro- and anti-inflammatory responses in lung tissue injury during the acute phase of PRRSV-1 infection with the virulent strain Lena
Q38879361Alarmin(g) the innate immune system to invasive fungal infections
Q37093517Arteriviruses, Pegiviruses, and Lentiviruses Are Common among Wild African Monkeys
Q37668276Dynamic changes in bronchoalveolar macrophages and cytokines during infection of pigs with a highly or low pathogenic genotype 1 PRRSV strain
Q38307388Host-pathogen interactions during porcine reproductive and respiratory syndrome virus 1 infection of piglets
Q41994293IL-1α is Critical for Resistance Against Highly Virulent Aspergillus fumigatus Isolates.
Q92904530In vitro characterization of PRRSV isolates with different in vivo virulence using monocyte-derived macrophages
Q40296676Porcine reproductive and respiratory syndrome type 1 viruses induce hypoplasia of erythroid cells and myeloid cell hyperplasia in the bone marrow of experimentally infected piglets independently of the viral load and virulence.
Q64885139Porcine reproductive and respiratory syndrome virus infection of bone marrow: Lesions and pathogenesis.
Q40690311Thymic depletion of lymphocytes is associated with the virulence of PRRSV-1 strains
Q91697477Virulent Lena strain induced an earlier and stronger downregulation of CD163 in bronchoalveolar lavage cells

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