A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae. (scientific article published on March 2015)

Improving the lethal effect of cpl-7, a pneumococcal phage lysozyme with broad bactericidal activity, by inverting the net charge of its cell wall-binding module

Q37263537

Biofilm formation in Streptococcus pneumoniae

Q37929875

Endolysins as antimicrobials

Q38022881

In vitro destruction of Streptococcus pneumoniae biofilms with bacterial and phage peptidoglycan hydrolases

Q38282910

Carboxy-terminal deletion analysis of the major pneumococcal autolysin

Q39932543

Structural studies of the lysozyme coded by the pneumococcal phage Cp-1. Conformational changes induced by choline

Q41241710

Insights into the structure-function relationships of pneumococcal cell wall lysozymes, LytC and Cpl-1.

Q42030822

Chimeric Ply187 endolysin kills Staphylococcus aureus more effectively than the parental enzyme

Q43117931

Beta-lactam modification of the bacteraemic profile and its relationship with mortality in a pneumococcal mouse sepsis model.

Q43869472

A study of the genetic material determining an enzyme activity in Pneumococcus

Q44711463

Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model.

Q45172053

Breakthrough in penicillin resistance? Streptococcus pneumoniae isolates with penicillin/cefotaxime MICs of 16 mg/L and their genotypic and geographical relatedness

Q45346556

Phage lytic enzyme Cpl-1 for antibacterial therapy in experimental pneumococcal meningitis

Q46602101

Structures of two cell wall-associated polysaccharides of aStreptococcus mitisbiovar 1 strain

Q58234577

Vancomycin tolerance in Gram-positive cocci

Q59261550

Versatility of the capsular genes during biofilm formation byStreptococcus pneumoniae

Q59261556

Genome of the Bacterium Streptococcus pneumoniae Strain R6

Q22065464

Bacteriophage lysins as effective antibacterials

Q24648457

PROCHECK: a program to check the stereochemical quality of protein structures

Q26778411

A new lysozyme fold. Crystal structure of the muramidase from Streptomyces coelicolor at 1.65 A resolution

Q27632782

Structural basis for selective recognition of pneumococcal cell wall by modular endolysin from phage Cp-1

Q27642277

The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis

Q27643380

Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1

Q27646137

Role of Net Charge on Catalytic Domain and Influence of Cell Wall Binding Domain on Bactericidal Activity, Specificity, and Host Range of Phage Lysins

Q27671535

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

Q27860503

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

Q27860847

Assessment of protein models with three-dimensional profiles

Q28283805

Cpl-7, a lysozyme encoded by a pneumococcal bacteriophage with a novel cell wall-binding motif

Q30392766

Peptidoglycan hydrolase fusions maintain their parental specificities

Q30446323

Amidase domains from bacterial and phage autolysins define a family of gamma-D,L-glutamate-specific amidohydrolases

Q33187139

Biofilm formation by Streptococcus pneumoniae: role of choline, extracellular DNA, and capsular polysaccharide in microbial accretion

Q33255474

Mass spectrometric characterization of glycated beta-lactoglobulin peptides derived from galacto-oligosaccharides surviving the in vitro gastrointestinal digestion

Q33333202

Chimeric phage-bacterial enzymes: a clue to the modular evolution of genes

Q33851733

Thermal stability of Cpl-7 endolysin from the streptococcus pneumoniae bacteriophage Cp-7; cell wall-targeting of its CW_7 motifs

Q34441804

The lytic enzyme of the pneumococcal phage Dp-1: a chimeric lysin of intergeneric origin

Q34447410

Taking aim on bacterial pathogens: from phage therapy to enzybiotics

Q34695345

Bacteriophages: evolution of the majority

Q34776752

Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6.

Q35634221

Recent trends on the molecular biology of pneumococcal capsules, lytic enzymes, and bacteriophage

Q35946160

Bacteriophage endolysins--current state of research and applications

Q36175326

Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant Staphylococcus aureus

Q37026612

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

Streptococcus pneumoniae

Q221179

P304

page(s)

1763-1773

P577

publication date

2015-03-01

P1433

published in

Journal of Antimicrobial Chemotherapy

Q6294770

P1476

title

A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae

P478

volume

Reverse relations

cites work (P2860)

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