Hydroxysafflor yellow A improves learning and memory in a rat model of vascular dementia by increasing VEGF and NR1 in the hippocampus

scientific article published on 23 August 2013

Hydroxysafflor yellow A improves learning and memory in a rat model of vascular dementia by increasing VEGF and NR1 in the hippocampus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12264-013-1375-2
P932PMC publication ID5562598
P698PubMed publication ID23979688

P2093author name stringNan Zhang
Yan Cheng
Zhuo Yang
Hao Liang
Fudong Shi
Yiyi Wang
Mengya Xing
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Morris water maze: procedures for assessing spatial and related forms of learning and memoryQ28296351
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Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiationQ28510000
VEGF links hippocampal activity with neurogenesis, learning and memoryQ28578381
Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptorsQ28581518
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The reorganization and reactivation of hippocampal maps predict spatial memory performanceQ30496132
Hydroxysafflor Yellow A protects spinal cords from ischemia/reperfusion injury in rabbitsQ33657340
Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factorsQ33814389
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Hippocampal synaptic plasticity and NMDA receptors: a role in information storage?Q37604104
Vascular risk factors and dementia: 40-year follow-up of a population-based cohortQ39724494
Mechanism of differential control of NMDA receptor activity by NR2 subunitsQ39858588
Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/BaxQ39955414
Expression of vascular endothelial growth factor and its receptors in rat neural stem cells.Q42443214
Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular developmentQ42626626
Acute hypoxia differentially affects the NMDA receptor NR1, NR2A and NR2B subunit mRNA levels in the developing chick optic tectum: stage-dependent plasticity in the 2B-2A ratioQ42993101
Effects of hydroxysafflor yellow A on the experimental traumatic brain injury in ratsQ43100310
Effects of hydroxysafflor yellow A in the attenuation of MPTP neurotoxicity in miceQ43292139
Effect of Hydroxysafflor yellow A on human umbilical vein endothelial cells under hypoxiaQ43673013
Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signalingQ44612704
Alterations of NMDA receptor subunits NR1, NR2A and NR2B mRNA expression and their relationship to apoptosis following transient forebrain ischemiaQ45591493
Hydroxysafflor yellow A protects neuron against hypoxia injury and suppresses inflammatory responses following focal ischemia reperfusion in ratsQ46372003
Biphasic effects of exogenous VEGF on VEGF expression of adult neural progenitorsQ46790213
NMDA receptors mediate calcium accumulation in myelin during chemical ischaemiaQ46863665
Cumulative long-term potentiation in the rat dentate gyrus correlates with, but does not modify, performance in the water mazeQ48314365
Impaired spatial learning after saturation of long-term potentiationQ48390196
Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor.Q51019927
Distinct components of spatial learning revealed by prior training and NMDA receptor blockade.Q52050936
Characterization of vascular permeability factor/vascular endothelial growth factor receptors on mononuclear phagocytesQ70708316
Two new quinochalcone yellow pigments from Carthamus tinctorius and Ca2+ antagonistic activity of tinctormineQ72708138
Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factorQ80783829
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectvascular dementiaQ583908
P304page(s)417-424
P577publication date2013-08-23
P1433published inNeuroscience BulletinQ15764540
P1476titleHydroxysafflor yellow A improves learning and memory in a rat model of vascular dementia by increasing VEGF and NR1 in the hippocampus
P478volume30

Reverse relations

cites work (P2860)
Q35827060De Novo Sequencing and Analysis of the Safflower Transcriptome to Discover Putative Genes Associated with Safflor Yellow in Carthamus tinctorius L
Q58596021Hydroxysafflor Yellow A (HSYA) Improves Learning and Memory in Cerebral Ischemia Reperfusion-Injured Rats via Recovering Synaptic Plasticity in the Hippocampus
Q57821474Hydroxysafflor Yellow A: A Promising Therapeutic Agent for a Broad Spectrum of Diseases
Q40105084Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a Systemic Th1 Bias
Q33699950NGF and TERT co-transfected BMSCs improve the restoration of cognitive impairment in vascular dementia rats
Q38808909Phytochemistry and Pharmacology of Carthamus tinctorius L.
Q43191065Protective effects of tao-Hong-si-wu decoction on memory impairment and hippocampal damage in animal model of vascular dementia.
Q41884186The effect of Scutellaria baicalensis stem-leaf flavonoids on spatial learning and memory in chronic cerebral ischemia-induced vascular dementia of rats
Q47769719Voluntary running-enhanced synaptic plasticity, learning and memory are mediated by Notch1 signal pathway in C57BL mice

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