Jun-Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency

scientific article published on 6 February 2016

Jun-Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.2294
P932PMC publication ID4864893
P698PubMed publication ID26850660

P2093author name stringAndrew D Sharrocks
Shen-Hsi Yang
Yaoyong Li
Giulia Veluscek
P2860cites workNotch promotes neural lineage entry by pluripotent embryonic stem cellsQ21146059
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identitiesQ24617969
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The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell statesQ27021125
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Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cellsQ28176681
The oncogene c-Jun impedes somatic cell reprogrammingQ28263863
Developmental defects in mouse embryos lacking N-cadherinQ28302581
CNS stem cells express a new class of intermediate filament proteinQ28577391
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewalQ28586947
c-Jun is essential for organization of the epidermal leading edgeQ28588242
Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3Q28594750
Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewalQ28910178
The ground state of embryonic stem cell self-renewalQ29547196
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Naive and primed pluripotent statesQ29616638
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monocultureQ29616806
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectinQ29617865
The extracellular matrix in development and morphogenesis: a dynamic viewQ30432483
α6β1- and αV-integrins are required for long-term self-renewal of murine embryonic stem cells in the absence of LIFQ30624291
Genome-wide gain-of-function screen identifies novel regulators of pluripotencyQ33632455
Otx2 and Oct4 drive early enhancer activation during embryonic stem cell transition from naive pluripotencyQ33818368
Chromatin immunoprecipitation and microarray-based analysis of protein locationQ34003310
E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogrammingQ34187775
Integrins regulate mouse embryonic stem cell self-renewal.Q50928305
Impaired intervertebral disc formation in the absence of Jun.Q52112240
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c-Jun is essential for normal mouse development and hepatogenesisQ57083732
A chromatin-modifying function of JNK during stem cell differentiationQ83010859
E-cadherin and, in its absence, N-cadherin promotes Nanog expression in mouse embryonic stem cells via STAT3 phosphorylationQ84373219
IntegrinsQ84435469
The developmental dismantling of pluripotency is reversed by ectopic Oct4 expressionQ34279160
AP-1 in mouse development and tumorigenesisQ34279346
A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation.Q34524686
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issuesQ34545153
Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytesQ34740852
Isolation of epiblast stem cells from preimplantation mouse embryos.Q34774985
Functions of AP1 (Fos/Jun) in bone developmentQ34963037
Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiationQ35710106
The transcriptional and epigenomic foundations of ground state pluripotency.Q36100410
Loss of Oct4 expression during the development of murine embryoid bodiesQ36336566
Endogenous production of fibronectin is required for self-renewal of cultured mouse embryonic stem cellsQ36638727
Tbx6, a mouse T-Box gene implicated in paraxial mesoderm formation at gastrulationQ36836682
Fibronectin and integrin alpha 5 play requisite roles in cardiac morphogenesisQ37324702
Epigenetic states in stem cellsQ37326991
Fibronectin receptor functions in embryonic cells deficient in alpha 5 beta 1 integrin can be replaced by alpha V integrinsQ37383250
AP-1--The Jun proteins: Oncogenes or tumor suppressors in disguise?Q37671290
Derivation of naive human embryonic stem cells.Q37674318
Epiblast stem cells contribute new insight into pluripotency and gastrulationQ37713945
The ground state of pluripotency.Q37775668
Self-organizing circuitry and emergent computation in mouse embryonic stem cells.Q37968423
Transcription regulation and chromatin structure in the pluripotent ground stateQ38149695
Negative regulation of Jun/AP-1: conserved function of glycogen synthase kinase 3 and the Drosophila kinase shaggyQ38320595
Tcf15 primes pluripotent cells for differentiation.Q39262489
Analysis of the distinct functions of growth factors and tissue culture substrates necessary for the long-term self-renewal of human embryonic stem cell linesQ39854302
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regenerationQ40803369
Reorganization of enhancer patterns in transition from naive to primed pluripotencyQ41428658
Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cellsQ41563760
MAP kinase-mediated c-fos regulation relies on a histone acetylation relay switchQ41834867
Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiationQ42001009
Generation of naive induced pluripotent stem cells from rhesus monkey fibroblasts.Q42686298
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocystsQ42771254
A genome-wide RNAi screen identifies a new transcriptional module required for self-renewalQ43148740
Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alphavbeta5 integrinQ46502991
Derivation of novel human ground state naive pluripotent stem cellsQ46977037
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P921main subjectcell adhesionQ187640
pluripotencyQ1894941
P304page(s)1213-1224
P577publication date2016-02-06
P1433published inStem CellsQ15724411
P1476titleJun-Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency
P478volume34

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cites work (P2860)
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Q47356876Small RNA Sequencing Reveals Dlk1-Dio3 Locus-Embedded MicroRNAs as Major Drivers of Ground-State Pluripotency.
Q94415931The Stagnant Adaptation of Defined and Xeno-Free Culture of iPSCs in Academia
Q33796203The many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states

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