| scholarly article | Q13442814 |
| P50 | author | Makoto Taniguchi | Q41463529 |
| Kazuyuki Kitatani | Q41463535 | ||
| P2093 | author name string | Hisanori Umehara | |
| Toshiro Okazaki | |||
| Yasuyuki Igarashi | |||
| Junzo Kigawa | |||
| Satoshi Asano | |||
| Tadakazu Kondo | |||
| Susumu Mitsutake | |||
| Akira Hayashi | |||
| Hiroyuki Takeya | |||
| Mayumi Hashimoto-Nishimura | |||
| P2860 | cites work | Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway | Q22253210 |
| Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1 | Q24314828 | ||
| Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids | Q24316056 | ||
| Mammalian autophagy: core molecular machinery and signaling regulation | Q24595447 | ||
| LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing | Q24597817 | ||
| The sphingolipid salvage pathway in ceramide metabolism and signaling | Q24642219 | ||
| The TSC1-TSC2 complex: a molecular switchboard controlling cell growth | Q24645204 | ||
| A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION | Q25939000 | ||
| TOR signaling in growth and metabolism | Q27860757 | ||
| Autophagy fights disease through cellular self-digestion | Q27860902 | ||
| Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6 | Q28141106 | ||
| Characterization of a novel sphingosine 1-phosphate receptor, Edg-8 | Q28143704 | ||
| Lysophospholipids--receptor revelations | Q28208260 | ||
| Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1 | Q28245694 | ||
| Principles of bioactive lipid signalling: lessons from sphingolipids | Q28265743 | ||
| Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals | Q28295232 | ||
| Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. | Q42555356 | ||
| Mutation of the Rb1 pathway leads to overexpression of mTor, constitutive phosphorylation of Akt on serine 473, resistance to anoikis, and a block in c-Raf activation | Q42614170 | ||
| Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells | Q42823066 | ||
| Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3. | Q43684832 | ||
| Truncation of the N-terminal ectodomain has implications in the N-glycosylation and transport to the cell surface of Edg-1/S1P1 receptor | Q44701394 | ||
| Sphingosine kinase activity counteracts ceramide-mediated cell death in human melanoma cells: role of Bcl-2 expression | Q45215121 | ||
| Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity | Q46606786 | ||
| Ceramide activates heterotrimeric protein phosphatase 2A. | Q48246807 | ||
| Identification of Leu276 of the S1P1 receptor and Phe263 of the S1P3 receptor in interaction with receptor specific agonists by molecular modeling, site-directed mutagenesis, and affinity studies. | Q51801416 | ||
| Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles. | Q55064927 | ||
| Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation | Q69785959 | ||
| Involvement of pertussis toxin-sensitive GTP-binding proteins in sphingosine 1-phosphate-induced activation of phospholipase C-Ca2+ system in HL60 leukemia cells | Q71006808 | ||
| Suppression of heat shock protein-70 by ceramide in heat shock-induced HL-60 cell apoptosis | Q73561165 | ||
| Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration | Q28583136 | ||
| Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3 | Q29614176 | ||
| Role of autophagy in cancer | Q29620348 | ||
| Sphingosine-1-phosphate: an enigmatic signalling lipid | Q29620563 | ||
| Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells | Q33183772 | ||
| Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate. | Q33773569 | ||
| Regulation of autophagy by sphingosine kinase 1 and its role in cell survival during nutrient starvation | Q34484983 | ||
| Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors | Q34691480 | ||
| Sphingosine 1-phosphate as a therapeutic agent | Q34802499 | ||
| Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells | Q34979866 | ||
| mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia | Q35003274 | ||
| Sphingosine kinase, sphingosine-1-phosphate, and apoptosis | Q35047178 | ||
| Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy | Q35092604 | ||
| Biologically active sphingolipids in cancer pathogenesis and treatment | Q35852313 | ||
| Disruption of ceramide synthesis by CerS2 down-regulation leads to autophagy and the unfolded protein response. | Q36155852 | ||
| The ins and outs of sphingolipid synthesis | Q36161646 | ||
| The role of autophagy in cancer development and response to therapy. | Q36251939 | ||
| Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy | Q36628922 | ||
| 1-beta-D-Arabinofuranosylcytosine stimulates ceramide and diglyceride formation in HL-60 cells | Q36751466 | ||
| PI3K/mTORC1 activation in hamartoma syndromes: therapeutic prospects | Q37032524 | ||
| Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy | Q37075287 | ||
| Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells | Q37147627 | ||
| Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation | Q37172903 | ||
| The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. | Q37319760 | ||
| Phosphorylation of the immunomodulator FTY720 inhibits programmed cell death of fibroblasts via the S1P3 receptor subtype and Bcl-2 activation | Q37760689 | ||
| S1P(5) is required for sphingosine 1-phosphate-induced autophagy in human prostate cancer PC-3 cells. | Q39846364 | ||
| Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM. | Q39918988 | ||
| Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression. | Q40002514 | ||
| Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis. | Q40310350 | ||
| The coordination of prostaglandin E2 production by sphingosine-1-phosphate and ceramide-1-phosphate | Q40420944 | ||
| Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. | Q40541165 | ||
| FAS activation induces dephosphorylation of SR proteins; dependence on the de novo generation of ceramide and activation of protein phosphatase 1. | Q40786419 | ||
| Functions of ceramide in coordinating cellular responses to stress | Q41243489 | ||
| Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology | Q41328049 | ||
| Regulation of ceramide production and apoptosis | Q41748407 | ||
| Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics | Q42163759 | ||
| Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid | Q42474499 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 47 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sirolimus | Q32089 |
| autophagy | Q288322 | ||
| sphingolipids | Q410395 | ||
| ceramides | Q424213 | ||
| P304 | page(s) | 39898-39910 | |
| P577 | publication date | 2012-10-03 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Regulation of autophagy and its associated cell death by "sphingolipid rheostat": reciprocal role of ceramide and sphingosine 1-phosphate in the mammalian target of rapamycin pathway | |
| P478 | volume | 287 |
| Q52878869 | Acid sphingomyelinase, autophagy, and atherosclerosis. |
| Q104795150 | Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis |
| Q37649641 | Activation of mTOR (mechanistic target of rapamycin) in rheumatic diseases |
| Q35225431 | Autophagy in the light of sphingolipid metabolism |
| Q26828523 | Autophagy paradox and ceramide |
| Q37645459 | C2-ceramide induces cell death and protective autophagy in head and neck squamous cell carcinoma cells |
| Q45073659 | CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation. |
| Q28384389 | Ceramide induced mitophagy and tumor suppression |
| Q36350326 | Ceramides And Stress Signalling Intersect With Autophagic Defects In Neurodegenerative Drosophila blue cheese (bchs) Mutants |
| Q34412400 | Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis |
| Q38831997 | Delivery systems of ceramide in targeted cancer therapy: ceramide alone or in combination with other anti-tumor agents |
| Q90682395 | Diverse Facets of Sphingolipid Involvement in Bacterial Infections |
| Q96172470 | Emerging roles of ATG proteins and membrane lipids in autophagosome formation |
| Q37295253 | Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin |
| Q30829403 | Evidence for the involvement of GD3 ganglioside in autophagosome formation and maturation. |
| Q57486638 | Extracellular Vesicles: How Drug and Pathology Interfere With Their Biogenesis and Function |
| Q47144572 | Fingolimod suppresses neuronal autophagy through the mTOR/p70S6K pathway and alleviates ischemic brain damage in mice. |
| Q35034843 | Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells |
| Q90516042 | Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis |
| Q22676705 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) |
| Q36097185 | High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer |
| Q40836525 | Involvement of sphingolipids in ethanol neurotoxicity in the developing brain |
| Q38966211 | Lipid catabolism via CPT1 as a therapeutic target for prostate cancer |
| Q43490949 | Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia |
| Q41952712 | Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans |
| Q33909832 | Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death |
| Q38889429 | Lysosomal ceramide generated by acid sphingomyelinase triggers cytosolic cathepsin B-mediated degradation of X-linked inhibitor of apoptosis protein in natural killer/T lymphoma cell apoptosis |
| Q92973905 | Neural sphingosine 1-phosphate accumulation activates microglia and links impaired autophagy and inflammation |
| Q33947149 | Preconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons |
| Q42959241 | ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma |
| Q38868037 | Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells |
| Q36436579 | Regulation of dynein-mediated autophagosomes trafficking by ASM in CASMCs. |
| Q26996672 | Revisiting the sphingolipid rheostat: Evolving concepts in cancer therapy |
| Q38495744 | Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies |
| Q30853652 | SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production |
| Q92129011 | Sphingolipid/Ceramide Pathways and Autophagy in the Onset and Progression of Melanoma: Novel Therapeutic Targets and Opportunities |
| Q89977951 | Sphingolipids and Mitochondrial Dynamic |
| Q37586487 | Sphingolipids and lifespan regulation |
| Q28084945 | Sphingolipids as cell fate regulators in lung development and disease |
| Q36840840 | Sphingolipids in cardiovascular and cerebrovascular systems: Pathological implications and potential therapeutic targets |
| Q36462123 | Sphingolipids: regulators of crosstalk between apoptosis and autophagy |
| Q41547434 | Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy. |
| Q89710825 | Sphingosine 1-phosphate promotes the proliferation of olfactory ensheathing cells through YAP signaling and participates in the formation of olfactory nerve layer |
| Q97524749 | Targeting SphK2 Reverses Acquired Resistance of Regorafenib in Hepatocellular Carcinoma |
| Q38349925 | The emerging role of acid sphingomyelinase in autophagy |
| Q33720239 | The pleiotropic roles of sphingolipid signaling in autophagy |
| Q97531610 | The role of lipids in autophagy and its implication in neurodegeneration |
| Q57470205 | Tricyclic antidepressant amitriptyline inhibits autophagic flux and prevents tube formation in vascular endothelial cells |
| Q42450605 | Trk receptors need neutral sphingomyelinase activity to promote cell viability |
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