Design and synthesis of a novel tyrosine kinase inhibitor template

scientific article published on 27 March 2009

Design and synthesis of a novel tyrosine kinase inhibitor template is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BMC.2009.03.046
P932PMC publication ID2696309
P698PubMed publication ID19362847
P5875ResearchGate publication ID24274238

P2093author name stringStephan W Morris
Thomas R Webb
P Jake Slavish
Qin Jiang
Xiaoli Cui
P2860cites workSynthesis of methylene- and difluoromethylenephosphonate analogues of uridine-4-phosphate and 3-deazauridine-4-phosphateQ79395805
Imidazole moiety replacements in the 3-(1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one inhibitors of insulin-like growth factor receptor-1 (IGF-1R) to improve cytochrome P450 profileQ80070517
Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitorsQ80311130
4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinaseQ27648289
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphomaQ27851421
Activating mutations in ALK provide a therapeutic target in neuroblastomaQ27851452
Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinaseQ33232683
Generation of new synthetic scaffolds using framework libraries selected and refined via medicinal chemist synthetic expertiseQ33323436
Preparation of indoles from alpha-aminonitriles: A short synthesis of FGIN-1-27.Q34567353
An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanismsQ34625881
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profilingQ36288956
Asymmetric carbon-carbon coupling of phenols or anilines with aryllead triacetates.Q43983734
1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3 betaQ44708058
3-(2-aminoalkyl)-1-(2,6-difluorobenzyl)-5- (2-fluoro-3-methoxyphenyl)-6-methyl-uracils as orally bioavailable antagonists of the human gonadotropin releasing hormone receptorQ44950091
Potent, orally active corticotropin-releasing factor receptor-1 antagonists containing a tricyclic pyrrolopyridine or pyrazolopyridine coreQ46152844
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)3308-3316
P577publication date2009-03-27
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleDesign and synthesis of a novel tyrosine kinase inhibitor template
P478volume17

Reverse relations

cites work (P2860)
Q28393324ALK and NSCLC: Targeted therapy with ALK inhibitors
Q38074590ALK inhibitors: a new targeted therapy in the treatment of advanced NSCLC.
Q58867034Seven-Membered Rings

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