Identification of cellular targets of a series of boron heterocycles using TIPA II-A sensitive target identification platform

scientific article published on 4 June 2016

Identification of cellular targets of a series of boron heterocycles using TIPA II-A sensitive target identification platform is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BMC.2016.05.058
P932PMC publication ID4992540
P698PubMed publication ID27301675

P2093author name stringFeimeng Zhou
Isba Silva
H Howard Xu
Matthew S Ward
Michael P Groziak
Ewa Kosmowska
Elena Buglo
Divya Kanichar
Shakila Rahman
Felicia Chow
Kim P Tran
Lance Roppiyakuda
Michelle A Faust
Jameka Jefferson
Jeanie M Garcia
Walfre Martinez
P2860cites workExperimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655Q22065459
10 x '20 Progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of AmericaQ24601746
A mechanism of drug action revealed by structural studies of enoyl reductaseQ27734154
Triclosan targets lipid synthesisQ28279853
A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepaciaQ28548011
Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of AmericaQ29616084
Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological researchQ29619122
High-throughput screening of a diversity collection using biodefense category A and B priority pathogensQ30541139
The discovery of biaryl acids and amides exhibiting antibacterial activity against Gram-positive bacteriaQ33199025
Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12Q33273138
Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathwayQ33314589
Large-scale transposon mutagenesis of Mycoplasma pulmonisQ33331457
Dynamics of trimethoprim bound to dihydrofolate reductaseQ33576961
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.Q33954835
A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli.Q34107208
A genome-wide strategy for the identification of essential genes in Staphylococcus aureusQ34123679
Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial developmentQ35092525
A whole-cell assay for specific inhibitors of translation initiation in bacteria.Q35542404
Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screeningQ36054436
Crystallographic insights into the structure-activity relationships of diazaborine enoyl-ACP reductase inhibitors.Q36337901
Mutants of Escherichia coli permeable to actinomycinQ36453101
The targets of currently used antibacterial agents: lessons for drug discoveryQ36990384
Multiresistant Gram-negative infections: a global perspectiveQ37783875
Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layerQ38307812
Activity of the ketolide telithromycin is refractory to Erm monomethylation of bacterial rRNA.Q39651945
Mechanism of action of diazaborines.Q40854626
Preparation and antibacterial activities of new 1,2,3-diazaborine derivatives and analoguesQ42248018
Arabinose 5-phosphate isomerase as a target for antibacterial design: studies with substrate analogues and inhibitors.Q43833813
Synthesis, characterization, and antibacterial activity of structurally complex 2-acylated 2,3,1-benzodiazaborines and related compoundsQ46098028
A disk-diffusion-based target identification platform for antibacterials (TIPA): an inducible assay for profiling MOAs of antibacterial compoundsQ46831959
Over-expression of target genes as a mechanism of antibiotic resistance in bacteria.Q52866894
Antimicrobial activity of tryptanthrins in Escherichia coli.Q54387789
Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.Q54590227
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)3267-3275
P577publication date2016-06-04
P1433published inBioorganic & Medicinal ChemistryQ2904200
P1476titleIdentification of cellular targets of a series of boron heterocycles using TIPA II-A sensitive target identification platform
P478volume24

Search more.