Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis

scientific article published on 13 January 2015

Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JP270101
P698PubMed publication ID25665036

P50authorShea Ping YipQ40246343
P2093author name stringJohn A Rudd
Benjamin Y Yung
Bjorn T Tam
Lawrence W Chan
Thomas K Sin
Parco M Siu
Michael Ying
Cesar S Wong
P2860cites workDeubiquitination of p53 by HAUSP is an important pathway for p53 stabilizationQ24292930
The anthracyclines: will we ever find a better doxorubicin?Q28184842
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanQ28203572
Doxorubicin-induced carbonylation and degradation of cardiac myosin binding protein C promote cardiotoxicityQ28306329
Daunomycin-induced cardiotoxicity in children and adults. A review of 110 casesQ28330575
Sirtuin 1 (SIRT1) activation mediates sildenafil induced delayed cardioprotection against ischemia-reperfusion injury in miceQ28539039
Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1Q28567865
Protective effect of caspase inhibition on compression-induced muscle damageQ28583919
Resveratrol induces apoptosis by directly targeting Ras-GTPase-activating protein SH3 domain-binding protein 1Q30009351
SIRT1 mediates the protective function of Nkx2.5 during stress in cardiomyocytesQ33288803
Downregulation of Sirt1 as aging change in advanced heart failureQ33960005
Recommendations for chamber quantificationQ34491436
Analysis of skeletal muscle gene expression patterns and the impact of functional capacity in patients with systolic heart failureQ34781822
Effects of short-term endurance exercise training on acute doxorubicin-induced FoxO transcription in cardiac and skeletal muscleQ35141318
Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1.Q35868154
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitorQ36086859
Different effects of resveratrol on dose-related Doxorubicin-induced heart and liver toxicity.Q36467387
Heart transplant survival outcomes for adriamycin-dilated cardiomyopathyQ36585760
Supervillin-mediated suppression of p53 protein enhances cell survivalQ36685259
Chemosensetizing and cardioprotective effects of resveratrol in doxorubicin- treated animalsQ36922988
TNF induction of atrogin-1/MAFbx mRNA depends on Foxo4 expression but not AKT-Foxo1/3 signaling.Q36955861
A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome.Q37124125
Quantitative proteomic study identified cathepsin B associated with doxorubicin-induced damage in H9c2 cardiomyocytes.Q38492572
Protective effect of resveratrol against doxorubicin-induced cardiac toxicity and fibrosis in male experimental ratsQ42705162
Sesamin ameliorates doxorubicin-induced cardiotoxicity: involvement of Sirt1 and Mn-SOD pathwayQ42708512
Doxorubicin induces protein ubiquitination and inhibits proteasome activity during cardiotoxicityQ42711541
Recombinant human interleukin-1 receptor antagonist protects mice against acute doxorubicin-induced cardiotoxicityQ42989370
SIRT1 activation by curcumin pretreatment attenuates mitochondrial oxidative damage induced by myocardial ischemia reperfusion injuryQ43664767
Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heartQ44050017
Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathwayQ46079892
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytesQ46696596
Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathwayQ46847190
Use of resveratrol to improve the effectiveness of cisplatin and doxorubicin: study in human gynecologic cancer cell lines and in rodent heart.Q53625213
Daunorubicin therapy is associated with upregulation of E3 ubiquitin ligases in the heart.Q54530203
Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosisQ57116600
Elevated p53 expression is associated with dysregulation of the ubiquitin-proteasome system in dilated cardiomyopathyQ80979295
Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53Q83324440
P407language of work or nameEnglishQ1860
P577publication date2015-01-13
P1433published inJournal of PhysiologyQ7743612
P1476titleResveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis

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