Antipseudomonal agents exhibit differential pharmacodynamic interactions with human polymorphonuclear leukocytes against established biofilms of Pseudomonas aeruginosa

scientific article published on 2 February 2015

Antipseudomonal agents exhibit differential pharmacodynamic interactions with human polymorphonuclear leukocytes against established biofilms of Pseudomonas aeruginosa is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.04934-14
P932PMC publication ID4356800
P698PubMed publication ID25645829
P5875ResearchGate publication ID272083782

P50authorEmmanuel RoilidesQ61097982
Charalampos AntachopoulosQ90292616
Thomas J WalshQ108430075
Maria SimitsopoulouQ114417857
Athanasios ChatzimoschouQ114417858
P2860cites workExtracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilmsQ21090518
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Lung infections associated with cystic fibrosisQ30080000
Transcriptional modulation of bacterial gene expression by subinhibitory concentrations of antibioticsQ30874391
Compromised Host Defense on Pseudomonas aeruginosa Biofilms: Characterization of Neutrophil and Biofilm InteractionsQ33193706
Bactericidal activity of various antibiotics against biofilm-producing Pseudomonas aeruginosa.Q33233116
Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumoniaQ33612643
Enhancement of oxidative response and damage caused by human neutrophils to Aspergillus fumigatus hyphae by granulocyte colony-stimulating factor and gamma interferonQ33618882
Interactions between polymorphonuclear leukocytes and Pseudomonas aeruginosa biofilms on silicone implants in vivoQ34268901
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosaQ34623469
Contributions of antibiotic penetration, oxygen limitation, and low metabolic activity to tolerance of Pseudomonas aeruginosa biofilms to ciprofloxacin and tobramycinQ34720396
Pharmacology of amikacin in humansQ34907857
Activities of triazole-echinocandin combinations against Candida species in biofilms and as planktonic cellsQ34932922
Pseudomonas aeruginosa: resistance to the maxQ35084559
Differences in biofilm formation and antimicrobial resistance of Pseudomonas aeruginosa isolated from airways of mechanically ventilated patients and cystic fibrosis patientsQ35223347
Effects of subinhibitory concentrations of macrolide antibiotics on Pseudomonas aeruginosaQ35661306
Inverse regulation of biofilm formation and swarming motility by Pseudomonas aeruginosa PA14Q35759797
The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infectionsQ36750086
Steady-state pharmacokinetics of ciprofloxacin in plasma from patients with nosocomial pneumonia: penetration of the bronchial mucosaQ36757441
Recent advances in the microbiology of respiratory tract infection in cystic fibrosisQ37373050
Immunomodulatory properties of antibioticsQ37659061
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Pseudomonas aeruginosa: host defence in lung diseasesQ37781114
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Efficacy and safety of liposomal clarithromycin and its effect on Pseudomonas aeruginosa virulence factorsQ39172960
Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilmsQ40155064
Effect of low concentrations of quinolone antibiotics on bacterial virulence mechanismsQ41503309
Natural release of virulence factors in membrane vesicles by Pseudomonas aeruginosa and the effect of aminoglycoside antibiotics on their releaseQ41676362
A new microtitre plate screening method for evaluating the viability of aerobic respiring bacteria in high surface biofilmsQ42948082
Secretion of proteases by Pseudomonas aeruginosa biofilms exposed to ciprofloxacin.Q42949257
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Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosisQ43257270
Serum pharmacokinetics and sputum penetration of amikacin 30 mg/kg once daily and of ceftazidime 200 mg/kg/day as a continuous infusion in cystic fibrosis patientsQ43693161
Effect of subinhibitory concentration of piperacillin/tazobactam on Pseudomonas aeruginosaQ45020548
Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependentQ45256199
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytesQ46149392
Sub-inhibitory concentrations of ceftazidime and tobramycin reduce the quorum sensing signals of Pseudomonas aeruginosaQ46446718
Comparison of multiple methods for quantification of microbial biofilms grown in microtiter platesQ46835624
Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilmsQ46953124
Killing of gram-negative bacteria by ciprofloxacin within both healthy human neutrophils and neutrophils with inactivated O2-dependent bactericidal mechanismsQ50125752
Use of Pseudomonas biofilm susceptibilities to assign simulated antibiotic regimens for cystic fibrosis airway infection.Q51963612
Amikacin disrupts the cell envelope of Pseudomonas aeruginosa ATCC 9027.Q52490764
Comparison of cefodizime with various cephalosporins for their indirect effect on the human neutrophil oxidative burst in vitro.Q54312846
Enhancement of leucocyte killing of resistant bacteria selected during exposure to aminoglycosides or quinolones.Q54323509
Multiple bacterial species reside in chronic wounds: a longitudinal studyQ57284132
Antimicrobial activity of subinhibitory concentrations of aminoglycosides against Pseudomonas aeruginosa as determined by the killing-curve method and the postantibiotic effectQ67988320
Single-dose pharmacokinetics of oral ciprofloxacin in patients with cystic fibrosisQ69991151
Permeation of antimicrobial agents through Pseudomonas aeruginosa biofilms: a simple methodQ73729017
In vitro activity of aminoglycosides on the respiratory burst response in human polymorphonuclear neutrophilsQ74633466
Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with pneumonia and estimation of its antibacterial effectsQ94706503
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectPseudomonas aeruginosaQ31856
biofilmQ467410
pharmacodynamicsQ725307
P304page(s)2198-2205
P577publication date2015-02-02
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleAntipseudomonal agents exhibit differential pharmacodynamic interactions with human polymorphonuclear leukocytes against established biofilms of Pseudomonas aeruginosa
P478volume59

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cites work (P2860)
Q40936412Activity of Tobramycin against Cystic Fibrosis Isolates of Burkholderia cepacia Complex Grown as Biofilms
Q36076102Preventing Data Ambiguity in Infectious Diseases with Four-Dimensional and Personalized Evaluations

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