| P50 | author | Jerry H Gurwitz | Q91395531 |
| P2093 | author name string | D. H. Solomon | |
| P2860 | cites work | Oxaprozin pharmacokinetics in the elderly | Q24544096 |
| | Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase | Q24563699 |
| | Age-associated decreases in prostaglandin contents in human gastric mucosa | Q33202224 |
| | The pharmacokinetics of piroxicam in elderly persons with and without renal impairment | Q34345908 |
| | Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study | Q34394177 |
| | Pharmacokinetic profile of controlled release ketoprofen in elderly patients | Q34447006 |
| | Pharmacokinetics of ketoprofen in the elderly | Q34512945 |
| | Non-steroidal anti-inflammatory drugs and peptic ulcer perforation | Q34526085 |
| | Naproxen pharmacokinetics in the elderly | Q34621473 |
| | The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites | Q34622717 |
| | Effects of age and disease on the pharmacokinetics and pharmacodynamics of sulindac | Q34695329 |
| | Aspirin use in patients with major upper gastrointestinal bleeding and peptic-ulcer disease. A report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center | Q34699199 |
| | Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial | Q34720605 |
| | Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain | Q35953747 |
| | Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part I). | Q36539873 |
| | Non-steroidal anti-inflammatory drug ingestion: retrospective study of 272 bleeding or perforated peptic ulcers | Q36723729 |
| | Mechanisms of gastric mucosal injury and protection | Q37294971 |
| | Nonsteroidal anti-inflammatory drugs and peptic ulcer disease | Q37624998 |
| | Benzodiazepines of long and short elimination half-life and the risk of hip fracture | Q38367453 |
| | Implications of altered drug disposition in the elderly: studies of benzodiazepines | Q38367876 |
| | Pharmacokinetic projections for isoxicam and piroxicam in old and young subjects | Q70105589 |
| | Duodenal bicarbonate secretion in humans. Role of prostaglandins | Q70275646 |
| | Effects of age on the clinical pharmacokinetics of ibuprofen | Q70372150 |
| | Double-blind, placebo-controlled endoscopic comparison of the mucosal protective effects of misoprostol versus cimetidine on tolmetin-induced mucosal injury to the stomach and duodenum | Q70395207 |
| | Absorption and disposition of ibuprofen in the elderly | Q70612534 |
| | Pharmacokinetics of indomethacin in the elderly | Q70743653 |
| | Sex and age-related differences in the urinary excretion of TXB2 in normal human subjects: a possible pathophysiological role of TXA2 in the aged kidney | Q70973208 |
| | Effect of aging on 6-keto-PGF1 alpha levels in normotensive and essential hypertensive males | Q71244001 |
| | Biochemical gastroprotection from acute ulceration induced by aspirin and related drugs | Q71259554 |
| | Aging and heparin-related bleeding | Q71446191 |
| | Evaluating drugs after their approval for clinical use | Q72030575 |
| | The effect of age on circulating 6-keto-prostaglandin F1 alpha in humans | Q72059591 |
| | L-745,337: a selective inhibitor of cyclooxygenase-2 elicits antinociception but not gastric ulceration in rats | Q72263693 |
| | A study of manufacturer-supported trials of nonsteroidal anti-inflammatory drugs in the treatment of arthritis | Q72718482 |
| | Age-related reductions in gastric mucosal prostaglandin levels increase susceptibility to aspirin-induced injury in rats | Q72800597 |
| | Single-dose and steady-state pharmacokinetics of piroxicam in elderly vs young adults | Q93572872 |
| | Factors affecting the kinetics of two benzothiazine non-steroidal anti-inflammatory medicines, piroxicam and isoxicam | Q93646838 |
| | Nonsteroidal anti-inflammatory drug use and death from peptic ulcer in elderly persons | Q38517756 |
| | Role of endogenous prostaglandins in preventing gastrointestinal ulceration: induction of ulcers by antibodies to prostaglandins. | Q38596275 |
| | The pharmacokinetics of non-steroidal anti-inflammatory drugs in the elderly | Q39761044 |
| | Clinical Pharmacokinetics of Non-steroidal Anti-inflammatory Drugs | Q40157661 |
| | Renal syndromes associated with nonsteroidal antiinflammatory drugs | Q40168640 |
| | Pharmacokinetic Studies on Diclofenac Sodium in Young and Old Volunteers | Q40549577 |
| | Nonsteroidal antiinflammatory drugs and the gastrointestinal tract. The double-edged sword | Q40567516 |
| | Nonsteroidal anti-inflammatory drugs and the incidence of hospitalizations for peptic ulcer disease in elderly persons | Q40618049 |
| | Some of the factors that may mediate or modify the gastrointestinal mucosal damage induced by non-steroidal anti-inflammatory drugs | Q40699124 |
| | NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions | Q40722651 |
| | PGH synthase isoenzyme selectivity: the potential for safer nonsteroidal antiinflammatory drugs | Q40837975 |
| | Renal prostaglandins, effective renal plasma flow and glomerular filtration rate in healthy elderly subjects | Q41114584 |
| | Lipid peroxidation and free radical scavengers in Alzheimer's disease | Q41289314 |
| | Pharmacokinetics of Salicylates in Elderly | Q41494121 |
| | Effects of nabumetone on prostanoid biosynthesis in humans. | Q42276009 |
| | Nabumetone kinetics in the young and elderly | Q42660902 |
| | Pharmacokinetic observations on piroxicam in young adult, middle-aged and elderly patients | Q43261977 |
| | Parenteral ketorolac and risk of gastrointestinal and operative site bleeding. A postmarketing surveillance study | Q43497777 |
| | Misoprostol compared with sucralfate in the prevention of nonsteroidal anti-inflammatory drug-induced gastric ulcer. A randomized, controlled trial | Q44219950 |
| | Influence of renal failure, rheumatoid arthritis and old age on the pharmacokinetics of diflunisal | Q44418107 |
| | The influence of age on renal prostaglandin synthesis in man. | Q45822196 |
| | Prevalence and characteristics of multiple analgesic drug use in an elderly study group. | Q52106262 |
| | Risk of upper gastrointestinal bleeding and perforation associated with Individual non-steroidal anti-inflammatory drugs | Q57945428 |
| | Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs | Q58053744 |
| | A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats | Q60695447 |
| | Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory Drugs | Q67903664 |
| | The effect of age on piroxicam disposition in rheumatoid arthritis | Q67935869 |
| | Steady state pharmacokinetic profile of indomethacin in elderly patients and young volunteers | Q68019078 |
| | Fatal upper gastrointestinal hemorrhage or perforation among users and nonusers of nonsteroidal anti-inflammatory drugs in Saskatchewan, Canada 1983 | Q68090334 |
| | Steady state pharmacokinetics of naproxen in elderly rheumatics compared with young volunteers | Q68093516 |
| | Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons | Q68182979 |
| | A multiple dose pharmacokinetic and tolerance study of once daily 200 mg sustained-release flurbiprofen capsules in young and very elderly patients | Q68630601 |
| | Risk of acute upper gastrointestinal bleeding in patients with ulcerative disease and treatment with non-steroidal anti-inflammatory drugs (NSAIDs). Results from the Comprehensive Hospital Drug Monitoring Berne (CHDM) | Q68759748 |
| | Nonsteroidal anti-inflammatory drugs and gastrointestinal bleeding. A case-control study | Q68808649 |
| | The association of nonsteroidal anti-inflammatory drugs with upper gastrointestinal tract bleeding | Q68812075 |
| | The relative gastrointestinal toxicity of the nonsteroidal anti-inflammatory drugs | Q68822259 |
| | Reduction of aspirin-induced gastroduodenal mucosal damage with ranitidine | Q68901966 |
| | Pharmacokinetics of naproxen in elderly patients | Q69316438 |
| | Protective effect of sucralfate against aspirin-induced damage to the human gastric mucosa | Q69414199 |
| | Free radicals and lipid peroxidation in ethanol- or aspirin-induced gastric mucosal injury | Q69467591 |
| | Effects of aging on responses to furosemide | Q69573831 |
| | A pharmacokinetic study of the active metabolite of nabumetone in young healthy subjects and older arthritis patients | Q69649970 |
| | Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer | Q69877679 |
| | The role of arachidonic acid metabolites in gastrointestinal homeostasis. Biochemical, histological and clinical gastrointestinal effects | Q69900981 |
| | Prevention of NSAID-induced gastric ulcer with misoprostol: multicentre, double-blind, placebo-controlled trial | Q69927046 |
| | Etodolac kinetics in the elderly | Q69992843 |
| | Effects of age and sex on piroxicam disposition | Q70044211 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | risk factor | Q1475848 |
| P304 | page(s) | 208-215 | |
| P577 | publication date | 1997-02-01 | |
| P1433 | published in | American Journal of Medicine | Q2842959 |
| P1476 | title | Toxicity of nonsteroidal anti-inflammatory drugs in the elderly: is advanced age a risk factor? | |
| | Toxicity of Nonsteroidal Anti-Inflammatory Drugs in the Elderly: Is Advanced Age a Risk Factor? | |
| P478 | volume | 102 | |