Insight into the metabolic mechanism of Diterpene Ginkgolides on antidepressant effects for attenuating behavioural deficits compared with venlafaxine.

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Insight into the metabolic mechanism of Diterpene Ginkgolides on antidepressant effects for attenuating behavioural deficits compared with venlafaxine. is …
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scholarly articleQ13442814

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P356DOI10.1038/S41598-017-10391-1
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/s41598-017-10391-1
P932PMC publication ID5575021
P698PubMed publication ID28852120

P50authorShunjie BaiQ87134854
P2093author name stringWei Wang
Yu Han
Jianjun Chen
Xiaodong Zhang
Peng Xie
Zhao Liu
Zhi Chen
Hua Huang
Li Zeng
Haiyang Wang
Peng Shen
Qingchuan Hu
Zihong Liang
Xiongfei Xie
Siwen Gui
P2860cites workTargeting the glutamatergic system to treat major depressive disorder: rationale and progress to dateQ27004490
The Extrinsic Coagulation Pathway: a Biomarker for Suicidal Behavior in Major Depressive DisorderQ27349460
Comparative efficacy and acceptability of psychotherapies for depression in children and adolescents: A systematic review and network meta-analysisQ28262885
Sparse whole-genome sequencing identifies two loci for major depressive disorderQ28265101
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stressQ29618764
Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regionsQ29620063
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathyQ30557070
Using MetaboAnalyst 3.0 for Comprehensive Metabolomics Data AnalysisQ31127142
Signaling pathways underlying the antidepressant-like effect of inosine in miceQ33689441
Role of the adipose PPARγ-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviorsQ33790412
Comparative efficacy and tolerability of antidepressants for major depressive disorder in children and adolescents: a network meta-analysisQ34530566
Oral administration of inosine produces antidepressant-like effects in miceQ34659961
The CNS effects of Ginkgo biloba extracts and ginkgolide B.Q34778214
Cameroonian medicinal plants: pharmacology and derived natural productsQ35155222
A standardized protocol for repeated social defeat stress in mice.Q35561938
1H NMR-based metabolic profiling reveals the effects of fluoxetine on lipid and amino acid metabolism in astrocytes.Q35585693
Involvement of the catecholaminergic system on the antidepressant-like effects of Alpinia zerumbet in mice.Q35606297
Identification and validation of urinary metabolite biomarkers for major depressive disorderQ36508139
TagFinder for the quantitative analysis of gas chromatography--mass spectrometry (GC-MS)-based metabolite profiling experiments.Q50657835
Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems.Q50705251
Serum levels of excitatory amino acids, serine, glycine, histidine, threonine, taurine, alanine and arginine in treatment-resistant depression: modulation by treatment with antidepressants and prediction of clinical responsivity.Q54139906
Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response.Q55034361
PAF antagonist ginkgolide B reduces postischemic neuronal damage in rat brain hippocampusQ68699960
Complementary cardioprotective effects of flavonoid metabolites and terpenoid constituents of Ginkgo biloba extract (EGb 761) during ischemia and reperfusionQ73250494
Antioxidative activity of natural products from plantsQ73461157
Effect of various classes of antidepressants in behavioral paradigms of despairQ80481523
Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress.Q36770623
Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression SusceptibilityQ36978291
The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effectsQ37067679
The antidepressant-like effect of inosine in the FST is associated with both adenosine A1 and A 2A receptors.Q37131954
Insight into the metabolic mechanism of scoparone on biomarkers for inhibiting Yanghuang syndromeQ37424787
Frequency dependant topological alterations of intrinsic functional connectome in major depressive disorder.Q37502040
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illnessQ37752880
Prefrontal cortex output circuits guide reward seeking through divergent cue encodingQ38948174
Transport of ginkgolides with different lipophilicities based on an hCMEC/D3 cell monolayer as a blood-brain barrier cell modelQ38964414
Effects of gut microbiota on the microRNA and mRNA expression in the hippocampus of mice.Q39017815
Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression ProfilesQ39296220
Targeted Metabolomic Pathway Analysis and Validation Revealed Glutamatergic Disorder in the Prefrontal Cortex among the Chronic Social Defeat Stress Mice Model of DepressionQ39418875
Repeated social defeat causes increased anxiety-like behavior and alters splenocyte function in C57BL/6 and CD-1 miceQ42114896
Prefrontal cortex reactivity underlies trait vulnerability to chronic social defeat stressQ42848805
A prefrontal cortex-brainstem neuronal projection that controls response to behavioural challengeQ44186836
Reduction of prefrontal cortex glucose metabolism common to three types of depressionQ45097380
Omics Studies of the Murine Intestinal Ecosystem Exposed to Subchronic and Mild Social Defeat StressQ46507385
Metabolic profiling reveals disorder of amino acid metabolism in four brain regions from a rat model of chronic unpredictable mild stressQ46513792
Gut microbiome remodeling induces depressive-like behaviors through a pathway mediated by the host's metabolismQ46565524
Ginsenoside Rg1-induced antidepressant effects involve the protection of astrocyte gap junctions within the prefrontal cortexQ47382247
The identification of metabolic disturbances in the prefrontal cortex of the chronic restraint stress rat model of depressionQ47444989
GC-MS-based metabolomic study on the antidepressant-like effects of diterpene ginkgolides in mouse hippocampusQ48046067
Peripheral blood mononuclear cell-based metabolomic profiling of a chronic unpredictable mild stress rat model of depressionQ48220933
Neurogenesis and major depression: implications from proteomic analyses of hippocampal proteins in a rat depression modelQ48236609
Amino acid metabolic dysfunction revealed in the prefrontal cortex of a rat model of depressionQ48287388
Dysfunctional glutamatergic and γ-aminobutyric acidergic activities in prefrontal cortex of mice in social defeat model of depressionQ48399737
Chronic social defeat stress model: behavioral features, antidepressant action, and interaction with biological risk factors.Q48469906
Neurobiology of Chronic Social Defeat Stress: Role of Brain-Derived Neurotrophic Factor Signaling in the Nucleus Accumbens.Q48549334
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)9591
P577publication date2017-08-29
P1433published inScientific ReportsQ2261792
P1476titleInsight into the metabolic mechanism of Diterpene Ginkgolides on antidepressant effects for attenuating behavioural deficits compared with venlafaxine
P478volume7

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cites work (P2860)
Q104795022CD36 deficiency affects depressive-like behaviors possibly by modifying gut microbiota and the inflammasome pathway in mice
Q92059662Diterpene Ginkgolides Exert an Antidepressant Effect Through the NT3-TrkA and Ras-MAPK Pathways
Q89747520Dl-3-n-butylphthalide attenuates mouse behavioral deficits to chronic social defeat stress by regulating energy metabolism via AKT/CREB signaling pathway
Q90353598Efficacy of ginkgo biloba extract as augmentation of venlafaxine in treating post-stroke depression
Q55714791Ginkgo biloba extract and its diterpene ginkgolide constituents ameliorate the metabolic disturbances caused by recombinant tissue plasminogen activator in rat prefrontal cortex.
Q93185341Urinary biomarkers for diagnosing poststroke depression in patients with type 2 diabetes mellitus

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