Human inter-α-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins

scientific article published on June 1, 1993

Human inter-α-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ2920485
P953full work available at URLhttps://europepmc.org/articles/pmc1134235?pdf=render
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7684902/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/7684902/pdf/?tool=EBI
https://europepmc.org/articles/PMC1134235
https://europepmc.org/articles/PMC1134235?pdf=render
https://portlandpress.com/biochemj/article-pdf/292/2/485/610723/bj2920485.pdf
P932PMC publication ID1134235
P698PubMed publication ID7684902
P5875ResearchGate publication ID21870371

P50authorMichel ScottéQ67469013
P2093author name stringJ. P. Lebreton
J. P. Salier
M. Daveau
M. Hiron
P. Rouet
L. Faye
P2860cites workAnalysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycanQ24295150
Human alpha 2-HS-glycoprotein: the A and B chains with a connecting sequence are encoded by a single mRNA transcriptQ24298954
Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TIQ24322991
Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomesQ24339444
The mRNA for a proteinase inhibitor related to the HI-30 domain of inter-alpha-trypsin inhibitor also encodes alpha-1-microglobulin (protein HC)Q24610509
Structure of the human alpha 1-acid glycoprotein gene: sequence homology with other human acute phase protein genesQ24622797
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Two out of the three kinds of subunits of inter-alpha-trypsin inhibitor are structurally relatedQ28237852
Isolation of human complex-forming glycoprotein, heterogeneous in charge (protein HC), and its IgA complex from plasma. Physiochemical and immunochemical properties, normal plasma concentrationQ28262770
Chondroitin 4-sulfate covalently cross-links the chains of the human blood protein pre-alpha-inhibitorQ28299940
cDNA cloning of human inter-alpha-trypsin inhibitor discloses three different proteinsQ28302439
Complementary DNA and derived amino acid sequence of the precursor of one of the three protein components of the inter-alpha-trypsin inhibitor complexQ28307324
Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigenQ29617963
Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure.Q30358808
Inter-α-trypsin inhibitor: emergence of a family within the Kunitz-type protease inhibitor superfamilyQ31066085
Interleukin-6 and the acute phase responseQ36559880
An intriguing member of the lipocalin protein family: α1-microglobulinQ36590461
Structure of inter-alpha-inhibitor (inter-alpha-trypsin inhibitor) and pre-alpha-inhibitor: current state and proposition of a new terminologyQ36596275
RNA blots: staining procedures and optimization of conditionsQ40531268
Effect of combinations of cytokines and hormones on synthesis of serum amyloid A and C-reactive protein in Hep 3B cellsQ41669884
Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.Q42488526
Identification of a factor in fetal bovine serum that stabilizes the cumulus extracellular matrix. A role for a member of the inter-alpha-trypsin inhibitor familyQ42602653
Inter-alpha-trypsin inhibitor and pre-alpha-trypsin inhibitor in health and disease. Determination by immunoelectrophoresis and immunoblottingQ45273110
The genes for the inter-alpha-inhibitor family share a homologous organization in human and mouseQ47305547
Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6Q58681737
Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytesQ58681791
Effects of cytokine combinations on acute phase protein production in two human hepatoma cell linesQ67687127
Electrophoretic pattern of the inter-alpha-inhibitor family proteins in human serum, characterized by chain-specific antibodiesQ67900458
Partial hepatectomy and mediators of inflammation decrease the expression of liver alpha 2-HS glycoprotein gene in ratsQ68582093
Human inter-alpha-trypsin inhibitor and immunologically related inhibitors investigated by quantitative immunoelectrophoresis. II. Pathological conditionsQ69783451
The synthesis of human alpha-2-HS glycoprotein is down-regulated by cytokines in hepatoma HepG2 cellsQ69844329
Human alpha 1-microglobulin in various hepatic disordersQ72714548
Inter-α-trypsin inhibitor (ITI): Use of new antisera for qualitative studies and discrete quantitation of ITI and its derivativesQ72716771
Quantitative study of human blood alpha-1-antitrypsin, alpha-2-macroglobulin and inter-alpha-trypsin-inhibitor with respect to plasma renin activityQ72720028
P407language of work or nameEnglishQ1860
P304page(s)485-492
P577publication date1993-06-01
P1433published inBiochemical JournalQ864221
P1476titleHuman inter-alpha-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins
Human inter-α-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins
P478volume292 ( Pt 2)

Reverse relations

cites work (P2860)
Q42168928Amino acid control of the human glyceraldehyde 3-phosphate dehydrogenase gene transcription in hepatocyte
Q28363374Anti-inflammatory and chondroprotective effect of TSG-6 (tumor necrosis factor-alpha-stimulated gene-6) in murine models of experimental arthritis
Q35753565Bikunin present in human peritoneal fluid is in part derived from the interaction of serum with peritoneal mesothelial cells
Q33845317Bikunin--not just a plasma proteinase inhibitor
Q54782705Biomarkers of necrotizing enterocolitis: a review of literature.
Q38305797Changes in hepatic gene expression related to innate immunity, growth and iron metabolism in GH-transgenic amago salmon (Oncorhynchus masou) by cDNA subtraction and microarray analysis, and serum lysozyme activity
Q40817002Characterization of binding properties of urinary trypsin inhibitor to cell-associated binding sites on human chondrosarcoma cell line HCS-2/8.
Q28286026Chondroitin sulphate covalently cross-links the three polypeptide chains of inter-alpha-trypsin inhibitor
Q35874524Constitutive expression of inter-α-inhibitor (IαI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
Q42137118Developmentally regulated transcription of the four liver-specific genes for inter-alpha-inhibitor family in mouse
Q77304258Down-regulation of negative acute-phase response genes by hypotonic stress in HepG2 hepatoma cells
Q48572623Electroacupuncture alters the expression of genes associated with lipid metabolism and immune reaction in liver of hypercholesterolemia mice
Q46739192Equivalent involvement of inter-alpha-trypsin inhibitor heavy chain isoforms in forming covalent complexes with hyaluronan
Q24532137Fetuin-B, a second member of the fetuin family in mammals
Q47964414Guinea pig alpha 1-microglobulin/bikunin: cDNA sequencing, tissue expression and expression during acute phase
Q40392837Hierarchy and positive/negative interplays of the hepatocyte nuclear factors HNF-1, -3 and -4 in the liver-specific enhancer for the human alpha-1-microglobulin/bikunin precursor
Q22003887Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage
Q50528660Human pre-alpha-inhibitor: isolation from a by-product of industrial scale plasma fractionation and structural analysis of its H3 heavy chain.
Q34756980ITIH4 (inter-alpha-trypsin inhibitor heavy chain 4) is a new acute-phase protein isolated from cattle during experimental infection
Q22010381ITIH4 serum concentration increases during acute-phase processes in human patients and is up-regulated by interleukin-6 in hepatocarcinoma HepG2 cells
Q34073697Immunocalins: a lipocalin subfamily that modulates immune and inflammatory responses.
Q33222559Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins
Q50282276Increased Levels of Serum Protein Complexes Are Associated with Type 2 Diabetes
Q47869639Inflammation and hemostasis in older octogenarians: implication in 5-year survival.
Q34217234Inter-alpha inhibitor protein level in neonates predicts necrotizing enterocolitis
Q73803055Inter-alpha inhibitor proteins in infants and decreased levels in neonatal sepsis
Q73815262Inter-alpha-inhibitor as marker for neutrophil proteinase activity: an in vitro investigation
Q83171368Modulation of plasma complement by the initial dose of epirubicin/docetaxel therapy in breast cancer and its predictive value
Q74382158Pig I alpha I appears unmodified in plasma in case of endotoxin-induced disseminated intravascular coagulation
Q57201057Pig MAP/ITIH4 and haptoglobin are interleukin-6-dependent acute-phase plasma proteins in porcine primary cultured hepatocytes
Q75352715Plasma and urine levels of urinary trypsin inhibitor in patients with chronic liver diseases and hepatocellular carcinoma
Q38588372Positive Mode LC-MS/MS Analysis of Chondroitin Sulfate Modified Glycopeptides Derived from Light and Heavy Chains of The Human Inter-α-Trypsin Inhibitor Complex.
Q34784822Proteomic profiling for the identification of serum diagnostic biomarkers for abdominal and thoracic aortic aneurysms
Q73164723Purification and characterization of pig inter-alpha-inhibitor and its constitutive heavy chains
Q30373164Structure and function of inter-alpha-trypsin inhibitor heavy chains.
Q34434369TSG-6: an IL-1/TNF-inducible protein with anti-inflammatory activity
Q43588608The chondroitin sulfate chain of bikunin-containing proteins in the inter-alpha-inhibitor family increases in size in inflammatory diseases
Q41377977The human inter-alpha-trypsin inhibitor genes respond differently to interleukin-6 in HepG2 cells
Q41008731The inter-alpha-inhibitor family: from structure to regulation
Q24292414The liver-specific human alpha(1)-microglobulin/bikunin precursor (AMBP) is capable of self-association
Q36677809The three heavy-chain precursors for the inter-alpha-inhibitor family in mouse: new members of the multicopper oxidase protein group with differential transcription in liver and brain
Q24530543Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A
Q80531948Upregulation of bikunin in tumor-infiltrating macrophages as a factor of favorable prognosis in ovarian cancer

Search more.