Annexin II is a major component of fusogenic endosomal vesicles

scientific article published on March 1993

Annexin II is a major component of fusogenic endosomal vesicles is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.120.6.1357
P932PMC publication ID2119741
P698PubMed publication ID8449982
P5875ResearchGate publication ID277479116

P50authorJean-Pierre GorvelQ37605858
P2093author name stringGriffiths G
Kellner R
Gruenberg J
Walter C
Gerke V
Emans N
P2860cites workCharacterization of Ca2(+)-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexinsQ24295082
Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartmentsQ24316079
β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptinQ24319220
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Calelectrin self-aggregates and promotes membrane aggregation in the presence of calciumQ26269960
Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zonesQ28211190
Diversity in the lipocortin/calpactin familyQ28285902
A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusionQ28291941
The GTPase superfamily: a conserved switch for diverse cell functionsQ28302983
Phase separation of integral membrane proteins in Triton X-114 solutionQ29547600
rab5 controls early endosome fusion in vitroQ29618144
The structure and function of the hemagglutinin membrane glycoprotein of influenza virusQ29618354
The small GTPase rab5 functions as a regulatory factor in the early endocytic pathwayQ29620272
A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeastQ29620584
Annexin-chromaffin granule membrane interactions: a comparative study of synexin, p32 and p67.Q30453779
Evaluation of the annexins as potential mediators of membrane fusion in exocytosisQ30454107
Aggregation of chromaffin granules by calpactin at micromolar levels of calciumQ30461394
Comprehensive two-dimensional gel protein databases offer a global approach to the analysis of human cells: the transformed amnion cells (AMA) master database and its link to genome DNA sequence dataQ33709313
Reconstitution of vesicle fusions occurring in endocytosis with a cell-free systemQ33880907
Identification and purification of an adrenal medullary protein (synexin) that causes calcium-dependent aggregation of isolated chromaffin granulesQ34255496
An internalized transmembrane protein resides in a fusion-competent endosome for less than 5 minutesQ34338966
Fusion between endocytic vesicles in a cell-free systemQ34598746
Hypervariable C-terminal domain of rab proteins acts as a targeting signalQ34981206
Genetic and biochemical analysis of vesicular traffic in yeastQ35455142
Regulation of intracellular membrane transport.Q35455158
Fusion of Semliki forest virus with the plasma membrane can be induced by low pH.Q36201795
Characterization of the early endosome and putative endocytic carrier vesicles in vivo and with an assay of vesicle fusion in vitroQ36220495
Isolation and preliminary characterization of the major membrane boundaries of the endocytic pathway in lymphocytes.Q36223921
Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesiclesQ36530046
The participation of annexin II (calpactin I) in calcium-evoked exocytosis requires protein kinase CQ36530258
Association of p60c-src with endosomal membranes in mammalian fibroblastsQ36533201
Synexin, a new member of the annexin gene family, is a calcium channel and membrane fusion proteinQ37892219
Synexin (annexin VII): a cytosolic calcium-binding protein which promotes membrane fusion and forms calcium channels in artificial bilayer and natural membranesQ37894621
Clathrin, adaptors, and sortingQ37902930
ExocytosisQ37918919
Biochemistry of interorganelle transport. A new frontier in enzymology emerges from versatile in vitro model systems.Q38235255
Tyrosine protein kinase substrate p36: a member of the annexin family of Ca2+/phospholipid-binding proteinsQ38262024
Membrane traffic in endocytosis: insights from cell-free assaysQ38311470
The annexin family of calcium-binding proteins. Review articleQ38642119
Cell-free systems to study vesicular transport along the secretory and endocytic pathwaysQ38710411
Calpactins: calcium-regulated membrane-skeletal proteinsQ39483997
Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.Q41618601
Inhibition of membrane fusion in vitro via cyclin B but not cyclin AQ41634208
Characterization of the mechanism of endocytic vesicle fusion in vitroQ41718649
Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cellsQ41724586
Movement of internalized ligand-receptor complexes along a continuous endosomal reticulumQ41727665
Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2.Q41757903
Consensus peptide antibodies reveal a widespread occurrence of Ca2+/lipid-binding proteins of the annexin familyQ41758647
Cell-free fusion of endocytic vesicles is regulated by phosphorylationQ41813156
Distribution of newly synthesized lysosomal enzymes in the endocytic pathway of normal rat kidney cellsQ41860842
Synaptophysin binds to physophilin, a putative synaptic plasma membrane proteinQ42015278
Reconstitution of GTP-binding Sar1 protein function in ER to Golgi transportQ42272523
Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surfaceQ42567664
Regulation of calpactin I phospholipid binding by calpactin I light-chain binding and phosphorylation by p60v-srcQ42856965
Mediation of the attachment or fusion step in vesicular transport by the GTP-binding Ypt1 proteinQ43485619
Scrutineer: a computer program that flexibly seeks and describes motifs and profiles in protein sequence databases.Q43818614
Annexin-mediated membrane fusion of human neutrophil plasma membranes and phospholipid vesiclesQ44885347
Calcium-dependent conformational changes in the 36-kDa subunit of intestinal protein I related to the cellular 36-kDa target of Rous sarcoma virus tyrosine kinaseQ45839113
A coat subunit of Golgi-derived non-clathrin-coated vesicles with homology to the clathrin-coated vesicle coat protein beta-adaptin.Q46034973
From G minor to G majorQ46798077
Primary structure and expression of the Xenopus laevis gene encoding annexin IIQ48215079
Binding of synaptotagmin to the alpha-latrotoxin receptor implicates both in synaptic vesicle exocytosisQ48656598
Vesicle fusion following receptor-mediated endocytosis requires a protein active in Golgi transportQ59068145
A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cellsQ59098879
Immuno-isolation of vesicles using antigenic sites either located on the cytoplasmic or the exoplasmic domain of an implanted viral protein. A quantitative analysis.Q64999230
Evidence of a role for heterotrimeric GTP-binding proteins in endosome fusionQ67515046
Annexin VI is required for budding of clathrin-coated pitsQ67546014
Two distinct subpopulations of endosomes involved in membrane recycling and transport to lysosomesQ68273722
Fusion between vesicles from the pathway of receptor-mediated endocytosis in a cell-free systemQ68309975
In vitro fusion of endosomes following receptor-mediated endocytosisQ68328305
Regulatory role for GTP-binding proteins in endocytosisQ69207001
Dissection of a single round of vesicular transport: sequential intermediates for intercisternal movement in the Golgi stackQ69327157
Immunoisolation using magnetic solid supports: subcellular fractionation for cell-free functional studiesQ69727293
Separation of two populations of endocytic vesicles involved in receptor-ligand sorting in rat hepatocytesQ70140316
On the preparation of cryosections for immunocytochemistryQ70806884
Reconstitution of an endocytic fusion event in a cell-free systemQ93658342
P433issue6
P407language of work or nameEnglishQ1860
P1104number of pages13
P304page(s)1357-1369
P577publication date1993-03-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleAnnexin II is a major component of fusogenic endosomal vesicles
P478volume120

Reverse relations

cites work (P2860)
Q74770834A Vacuole-Associated Annexin Protein, VCaB42, Correlates with the Expansion of Tobacco Cells
Q27640527A calcium-driven conformational switch of the N-terminal and core domains of annexin A1
Q40231734A combined proteomics and metabolomics approach to assess the effects of gold nanoparticles in vitro
Q41484383A qualitative and quantitative protein database approach identifies individual and groups of functionally related proteins that are differentially regulated in simian virus 40 (SV40) transformed human keratinocytes: an overview of the functional cha
Q41053875Acidic cytosolic proteins are preferentially imported into rat liver lysosomes
Q43558899Acidic pH generated by H+-ATPase pumps triggers the activity of a fusogenic protein associated with rat liver endoplasmic reticulum
Q28483637Altered protein expression in gestational diabetes mellitus placentas provides insight into insulin resistance and coagulation/fibrinolysis pathways
Q24671983An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes
Q40933665Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton
Q38819292Analysis of the effect of a novel therapeutic for type 2 diabetes on the proteome of a muscle cell line.
Q28583310Annexin 2 binding to phosphatidylinositol 4,5-bisphosphate on endocytic vesicles is regulated by the stress response pathway
Q28570986Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation
Q74386980Annexin 2 has an essential role in actin-based macropinocytic rocketing
Q34336252Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
Q36909958Annexin A2 Coordinates STAT3 to Regulate the Invasion and Migration of Colorectal Cancer Cells In Vitro
Q46259470Annexin A2 binding to endosomes and functions in endosomal transport are regulated by tyrosine 23 phosphorylation.
Q36242151Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway
Q36790362Annexin A2 heterotetramer: structure and function
Q40607858Annexin A2 is a novel RNA-binding protein
Q37327299Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina
Q36873692Annexin A2 regulates β1 integrin internalization and intestinal epithelial cell migration
Q37586765Annexin A2: its molecular regulation and cellular expression in cancer development
Q28248278Annexin I targets S100C to early endosomes
Q36237099Annexin II in exocytosis: catecholamine secretion requires the translocation of p36 to the subplasmalemmal region in chromaffin cells.
Q54590882Annexin II is a novel player in insulin signal transduction. Possible association between annexin II phosphorylation and insulin receptor internalization.
Q33195892Annexin II is required for apical transport in polarized epithelial cells
Q35160402Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells
Q40950533Annexin II tetramer: structure and function
Q24534144Annexin II up-regulates cellular levels of p11 protein by a post-translational mechanisms
Q31035483Annexin V, annexin VI, S100A1 and S100B in developing and adult avian skeletal muscles
Q74162441Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment
Q36255657Annexin VI-mediated loss of spectrin during coated pit budding is coupled to delivery of LDL to lysosomes
Q40862127Annexin XI may be involved in Ca2+ - or GTP-gammaS-induced insulin secretion in the pancreatic beta-cell
Q41946695Annexin XIIIb: a novel epithelial specific annexin is implicated in vesicular traffic to the apical plasma membrane
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Q29619942Annexins: linking Ca2+ signalling to membrane dynamics
Q83189092Anti-annexin II antibody is associated with thrombosis and/or pregnancy morbidity in antiphospholipid syndrome and systemic lupus erythematosus with thrombosis
Q73360684Antisense-mediated regulation of Annexin VII gene expression during the transition from growth to differentiation in Dictyostelium discoideum
Q33422993Anx2 interacts with HIV-1 Gag at phosphatidylinositol (4,5) bisphosphate-containing lipid rafts and increases viral production in 293T cells
Q38543749Atorvastatin protects endothelial colony‑forming cells against H2O2‑induced oxidative damage by regulating the expression of annexin A2
Q30698610BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes
Q44914359Biochemical and immunohistochemical characterization of Mimosa annexin
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Q40826317Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cells
Q24295231Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope
Q41285650Calcium-induced relocation of annexins IV and V in the human osteosarcoma cell line MG-63.
Q41120299Calmodulin regulates endosome fusion
Q38348733Carbohydrate Binding Activity of Annexin V toward a Bisecting N-Acetylglucosamine
Q38072986Ca²⁺-sensor proteins in the autophagic and endocytic traffic
Q35107630Cell-surface cathepsin B: Understanding its functional significance
Q24336097Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense
Q28137755Characterization of the calcyclin (S100A6) binding site of annexin XI-A by site-directed mutagenesis
Q44031840Cholesterol modulates the membrane binding and intracellular distribution of annexin 6.
Q43600578Cholesterol regulates membrane binding and aggregation by annexin 2 at submicromolar Ca(2+) concentration
Q38576133Comparative Microarray Analysis Identifies Commonalities in Neuronal Injury: Evidence for Oxidative Stress, Dysfunction of Calcium Signalling, and Inhibition of Autophagy-Lysosomal Pathway.
Q36534832Cytoplasmic dynein-dependent vesicular transport from early to late endosomes
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Q39614542Detergent-free isolation and characterization of cholesterol-rich membrane domains from trans-Golgi network vesicles.
Q36549374Direct interaction between human cytomegalovirus glycoprotein B and cellular annexin II.
Q24800536Discovery of mammalian genes that participate in virus infection
Q24305143Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display
Q34653675Domains I and IV of annexin A2 affect the formation and integrity of in vitro capillary-like networks
Q35748034Down-regulation of annexin A10 in hepatocellular carcinoma is associated with vascular invasion, early recurrence, and poor prognosis in synergy with p53 mutation
Q42675658Drainin required for membrane fusion of the contractile vacuole in Dictyostelium is the prototype of a protein family also represented in man
Q57364325Edman degradation and MALDI sequencing enables N- and C-terminal sequence analysis of peptides
Q41492371Endocytosis occurs independently of annexin VI in human A431 cells
Q40738554Endocytosis: aspects of organellar processing
Q41152896Endosomal fractions from viral K-ras-transformed MDCK cells reveal transformation specific changes on two-dimensional gel maps
Q43057653Enhanced eryptosis of erythrocytes from gene-targeted mice lacking annexin A7.
Q57362693Establishment of plasma membrane polarity in mammary epithelial cells correlates with changes in prolactin trafficking and in annexin VI recruitment to membranes
Q28579652Evidence for early endosome-like fusion of recently endocytosed synaptic vesicles
Q22253176Expression and localisation of annexin VII (synexin) isoforms in differentiating myoblasts
Q48266084Expression of annexin A2 in GABAergic interneurons in the normal rat brain
Q41080837Expression of placental alkaline phosphatase does not correlate with IgG binding, internalization and transcytosis
Q41450476Fc gamma-receptor activity of placental annexin II.
Q42770982Fluorescent choleretic and cholestatic bile salts take different paths across the hepatocyte: transcytosis of glycolithocholate leads to an extensive redistribution of annexin II.
Q28139003Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type
Q38613358Fusion of endosomes involved in synaptic vesicle recycling
Q41261836Gaining insight into a complex organelle, the phagosome, using two-dimensional gel electrophoresis.
Q41053884Generation of proteoliposomes from subcellular fractions.
Q37369869Glycogen synthase kinase-3 and Omi/HtrA2 induce annexin A2 cleavage followed by cell cycle inhibition and apoptosis
Q40130532Glycosylation and annexin II cell surface translocation mediate airway epithelial wound repair
Q39001579High expression of beta2-glycoprotein I is associated significantly with the earliest stages of hepatitis B virus infection
Q41732259High-resolution density gradient electrophoresis of proteins and subcellular organelles
Q35844376Host cellular annexin II is associated with cytomegalovirus particles isolated from cultured human fibroblasts
Q24310076Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies
Q28572420Identification and characterization of two distinct intracellular GLUT4 pools in rat skeletal muscle: evidence for an endosomal and an insulin-sensitive GLUT4 compartment
Q42830018Identification and partial sequence analysis of novel annexins in Lytechinus pictus oocytes
Q34567178Identification of an AHNAK binding motif specific for the Annexin2/S100A10 tetramer
Q24321353Identification of components of trans-Golgi network-derived transport vesicles and detergent-insoluble complexes by nanoelectrospray tandem mass spectrometry
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Q59705761In adrenocortical tissue, annexins II and VI are attached to clathrin coated vesicles in a calcium-independent manner1In memoriam: This last work as well as my scientific accomplishment are dedicated to the memory of Jeffries Wyman who was my best te
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Q36275035Involvement of the transmembrane protein p23 in biosynthetic protein transport
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Q34153450Lipid membrane domains in cell surface and vacuolar systems
Q40806941Localization of lysobisphosphatidic acid-rich membrane domains in late endosomes
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Q40685194New insights into the tPA-annexin A2 interaction. Is annexin A2 CYS8 the sole requirement for this association?
Q41255359Okadaic acid gives concentration-dependent reciprocal effects on the fluid phase endocytosis activated by Ca2+ and phorbol 12-myristate 13-acetate
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Q71841150Protein phosphorylation during phagosome maturation
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Q37641731Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting
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Q40830872Regulated exocytosis
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Q41053829Separation of early steps in endocytic membrane transport
Q36232566Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells
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Q33539181Subcellular fractionation, electromigration analysis and mapping of organelles
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Q29620568The Rab5 effector EEA1 is a core component of endosome docking
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Q29620561The biogenesis of multivesicular endosomes
Q24321243The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans
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Q40117334The formation of the cAMP/protein kinase A-dependent annexin 2-S100A10 complex with cystic fibrosis conductance regulator protein (CFTR) regulates CFTR channel function
Q35362775The human papillomavirus type 16 E5 oncoprotein translocates calpactin I to the perinuclear region
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Q28469335The p11/S100A10 light chain of annexin A2 is dispensable for annexin A2 association to endosomes and functions in endosomal transport
Q34745959The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components
Q42152854The subcellular distribution of early endosomes is affected by the annexin II2p11(2) complex
Q30727697The zebrafish annexin gene family.
Q35169907Transcytosis: crossing cellular barriers
Q41065741Transferrin receptor functions as a signal-transduction molecule for its own recycling via increases in the internal Ca2+ concentration
Q41053928Two-dimensional gel electrophoresis analysis of endovacuolar organelles
Q24305279p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1

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