| scholarly article | Q13442814 |
| P356 | DOI | 10.1006/VIRO.1993.1078 |
| P698 | PubMed publication ID | 8380666 |
| P2093 | author name string | Fraser NW | |
| Block TM | |||
| Maggioncalda J | |||
| Valyi-Nagi T | |||
| Deshmane S | |||
| Masonis J | |||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 618-630 | |
| P577 | publication date | 1993-02-01 | |
| P1433 | published in | Virology | Q7934867 |
| P1476 | title | An HSV LAT null mutant reactivates slowly from latent infection and makes small plaques on CV-1 monolayers | |
| P478 | volume | 192 |
| Q35859034 | A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation. |
| Q35891247 | A 437-base-pair deletion at the beginning of the latency-associated transcript promoter significantly reduced adrenergically induced herpes simplex virus type 1 ocular reactivation in latently infected rabbits |
| Q34330385 | A gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levels |
| Q35220431 | A herpes simplex virus type 1 mutant disrupted for microRNA H2 with increased neurovirulence and rate of reactivation |
| Q33984275 | A herpes simplex virus type 1 mutant expressing a baculovirus inhibitor of apoptosis gene in place of latency-associated transcript has a wild-type reactivation phenotype in the mouse. |
| Q44524649 | A mutant deleted for most of the herpes simplex virus type 1 (HSV-1) UOL gene does not affect the spontaneous reactivation phenotype in rabbits |
| Q45625417 | A non-consensus branch point plays an important role in determining the stability of the 2-kb LAT intron during acute and latent infections of herpes simplex virus type-1. |
| Q35000720 | A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits. |
| Q39683145 | A protein encoded by the herpes simplex virus (HSV) type 1 2-kilobase latency-associated transcript is phosphorylated, localized to the nucleus, and overcomes the repression of expression from exogenous promoters when inserted into the quiescent HSV |
| Q36637719 | Analysis of a herpes simplex virus type 1 LAT mutant with a deletion between the putative promoter and the 5' end of the 2.0-kilobase transcript. |
| Q33838578 | Analysis of protein expression from within the region encoding the 2.0-kilobase latency-associated transcript of herpes simplex virus type 1 |
| Q37080840 | Chromatin control of herpes simplex virus lytic and latent infection |
| Q36630170 | Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain. |
| Q37596877 | Construction of a herpes simplex virus type 1 mutant with only a three-nucleotide change in the branchpoint region of the latency-associated transcript (LAT) and the stability of its two-kilobase LAT intron |
| Q73733769 | Establishment and maintenance of HSV latent infection is mediated through correct splicing of the LAT primary transcript |
| Q35374610 | Experimental investigation of herpes simplex virus latency |
| Q36635409 | Expression of a herpes simplex virus 1 open reading frame antisense to the gamma(1)34.5 gene and transcribed by an RNA 3' coterminal with the unspliced latency-associated transcript. |
| Q73874722 | Herpes simplex type 2 infections--an update |
| Q33604367 | Herpes simplex virus 1 open reading frames O and P are not necessary for establishment of latent infection in mice |
| Q33817299 | Herpes simplex virus latency-associated transcript encodes a protein which greatly enhances virus growth, can compensate for deficiencies in immediate-early gene expression, and is likely to function during reactivation from virus latency |
| Q33558390 | Herpes simplex virus type 1 (HSV-1)-induced apoptosis in human dendritic cells as a result of downregulation of cellular FLICE-inhibitory protein and reduced expression of HSV-1 antiapoptotic latency-associated transcript sequences |
| Q33869971 | Herpes simplex virus type 1 2-kilobase latency-associated transcript intron associates with ribosomal proteins and splicing factors |
| Q36628122 | Herpes simplex virus type 1 DNA replication and gene expression during explant-induced reactivation of latently infected murine sensory ganglia |
| Q33884066 | Herpes simplex virus type 1 latency-associated transcript expression protects trigeminal ganglion neurons from apoptosis |
| Q39603582 | Herpes simplex virus type 1 latency-associated transcript gene promotes neuronal survival |
| Q39580809 | Herpes simplex virus type 1 latency-associated transcripts suppress viral replication and reduce immediate-early gene mRNA levels in a neuronal cell line |
| Q41154037 | Herpes simplex: evolving concepts |
| Q39550584 | Human corneal cells and other fibroblasts can stimulate the appearance of herpes simplex virus from quiescently infected PC12 cells. |
| Q37596468 | Human cytomegalovirus 5-kilobase immediate-early RNA is a stable intron |
| Q40463896 | Identification of a protein encoded in the herpes simplex virus type 1 latency associated transcript promoter region. |
| Q37584342 | Imino sugar glucosidase inhibitors as broadly active anti-filovirus agents |
| Q44480607 | In situ DNA PCR and RNA hybridization detection of herpes simplex virus sequences in trigeminal ganglia of latently infected mice |
| Q35871252 | In vivo epinephrine reactivation of ocular herpes simplex virus type 1 in the rabbit is correlated to a 370-base-pair region located between the promoter and the 5' end of the 2.0 kilobase latency-associated transcript |
| Q36366295 | Increased neurovirulence and reactivation of the herpes simplex virus type 1 latency-associated transcript (LAT)-negative mutant dLAT2903 with a disrupted LAT miR-H2 |
| Q33865985 | Inducible cyclic AMP early repressor produces reactivation of latent herpes simplex virus type 1 in neurons in vitro |
| Q36654914 | Induction of reactivation of herpes simplex virus in murine sensory ganglia in vivo by cadmium. |
| Q40075141 | Introducing point mutations into the ATGs of the putative open reading frames of the HSV-1 gene encoding the latency associated transcript (LAT) reduces its anti-apoptosis activity |
| Q37275033 | Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia. |
| Q37560704 | Mutations Inactivating Herpes Simplex Virus 1 MicroRNA miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia |
| Q37201603 | Ocular HSV-1 latency, reactivation and recurrent disease. |
| Q36636904 | PCR-based analysis of herpes simplex virus type 1 latency in the rat trigeminal ganglion established with a ribonucleotide reductase-deficient mutant. |
| Q35857171 | Phenotypic properties of herpes simplex virus 1 containing a derepressed open reading frame P gene. |
| Q45404803 | Reactivation phenotype in rabbits of a herpes simplex virus type 1 mutant containing an unrelated antiapoptosis gene in place of latency-associated transcript |
| Q34358232 | Regions of the herpes simplex virus type 1 latency-associated transcript that protect cells from apoptosis in vitro and protect neuronal cells in vivo |
| Q41905781 | Relaxed repression of herpes simplex virus type 1 genomes in Murine trigeminal neurons |
| Q35889694 | Selection of a nonconsensus branch point is influenced by an RNA stem-loop structure and is important to confer stability to the herpes simplex virus 2-kilobase latency-associated transcript |
| Q42670174 | Sequence and comparative analysis of the genome of HSV-1 strain McKrae |
| Q34668446 | Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosis |
| Q35880687 | The abundant latency-associated transcripts of herpes simplex virus type 1 are bound to polyribosomes in cultured neuronal cells and during latent infection in mouse trigeminal ganglia |
| Q35888512 | The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency |
| Q45404813 | The latency-associated transcript of herpes simplex virus type 1 promotes survival and stimulates axonal regeneration in sympathetic and trigeminal neurons |
| Q36586773 | The product of ORF O located within the domain of herpes simplex virus 1 genome transcribed during latent infection binds to and inhibits in vitro binding of infected cell protein 4 to its cognate DNA site |
| Q34742782 | The stable 2.0-kilobase intron of the herpes simplex virus type 1 latency-associated transcript does not function as an antisense repressor of ICP0 in nonneuronal cells |
| Q33845198 | Three herpes simplex virus type 1 latency-associated transcript mutants with distinct and asymmetric effects on virulence in mice compared with rabbits |
| Q36637944 | Two open reading frames (ORF1 and ORF2) within the 2.0-kilobase latency-associated transcript of herpes simplex virus type 1 are not essential for reactivation from latency |
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