| P50 | author | Alexandre F Fernandes | Q39979075 |
| | Paulo Pereira | Q39979124 |
| P2093 | author name string | Allen Taylor | |
| | Fu Shang | |
| | Janet R Sparrow | |
| | Xinyu Zhang | |
| | Jilin Zhou | |
| P2860 | cites work | HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing | Q24291102 |
| | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction | Q24292709 |
| | The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism | Q24298728 |
| | The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 |
| | Mechanisms underlying ubiquitination | Q27860656 |
| | Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation | Q27860876 |
| | A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways | Q28138489 |
| | Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha | Q28144122 |
| | Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents | Q28198084 |
| | Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium | Q28610021 |
| | Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway | Q28615591 |
| | Impairment of the ubiquitin-proteasome system by protein aggregation | Q29614556 |
| | Degradation of CFTR by the ubiquitin-proteasome pathway | Q29616142 |
| | Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2. | Q43592238 |
| | Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion | Q43619451 |
| | Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway | Q43669266 |
| | Involvement of oxidative mechanisms in blue-light-induced damage to A2E-laden RPE. | Q43940061 |
| | Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes | Q44007131 |
| | Ubiquitination capabilities in response to neocarzinostatin and H(2)O(2) stress in cell lines from patients with ataxia-telangiectasia | Q44039023 |
| | Relationship between glycoxidation and cytokines in the vitreous of eyes with diabetic retinopathy | Q44133634 |
| | Proteasome function and protein oxidation in the aged retina | Q44182667 |
| | Stability of the nuclear protein turnover during cellular senescence of human fibroblasts | Q44535787 |
| | Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells | Q44539005 |
| | Age-dependent protein modifications and declining proteasome activity in the human lens | Q44936414 |
| | 4-Hydroxynonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease. | Q46002386 |
| | Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells | Q46395223 |
| | Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes | Q46985940 |
| | Aging, calorie restriction and ubiquitin-dependent proteolysis in the livers of Emory mice | Q47987518 |
| | Resistance to cadmium mediated by ubiquitin-dependent proteolysis | Q48136378 |
| | Oxidized SOD1 alters proteasome activities in vitro and in the cortex of SOD1 overexpressing mice | Q48851182 |
| | Blue light-induced reactivity of retinal age pigment. In vitro generation of oxygen-reactive species. | Q50759187 |
| | Age-related decline in ubiquitin conjugation in response to oxidative stress in the lens. | Q52197477 |
| | Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway | Q71468319 |
| | Increased lipid peroxide level and myeloperoxidase activity in the vitreous of patients suffering from proliferative vitreoretinopathy | Q72510534 |
| | Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury | Q73107489 |
| | Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein | Q73204871 |
| | MDM2-dependent ubiquitination of nuclear and cytoplasmic P53 | Q73322471 |
| | Oxidative stress increases ubiquitin--protein conjugates in synaptosomes | Q73546423 |
| | Effect of oxidant systems on the ubiquitylation of proteins in the central nervous system | Q73561757 |
| | Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated | Q73674601 |
| | Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress | Q73699336 |
| | Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress | Q73836143 |
| | Ubiquitin-activating enzyme (E1) isoforms in lens epithelial cells: origin of translation, E2 specificity and cellular localization determined with novel site-specific antibodies | Q77642609 |
| | Calorie restriction, stress and the ubiquitin-dependent pathway in mouse livers | Q77714605 |
| | 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules | Q78122210 |
| | Protein degradation and protection against misfolded or damaged proteins | Q29618400 |
| | Degradation of oxidized proteins in mammalian cells. | Q30427697 |
| | Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity | Q30448692 |
| | Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. | Q30984629 |
| | Fluorophotometric detection of intravitreal peroxides after panretinal laser photocoagulation | Q32111336 |
| | Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting | Q33292109 |
| | The proteasome, a novel protease regulated by multiple mechanisms | Q33700949 |
| | A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal | Q33958676 |
| | Control of IkappaBalpha proteolysis by the ubiquitin-proteasome pathway | Q34214145 |
| | Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation. | Q34407193 |
| | The ubiquitin proteolytic system and pathogenesis of human diseases: a novel platform for mechanism-based drug targeting | Q35090962 |
| | Age-Related Macular Degeneration: Etiology, Pathogenesis, and Therapeutic Strategies | Q35126780 |
| | Function of the ubiquitin proteolytic pathway in the eye. | Q35604942 |
| | Age-dependent inhibition of proteasome chymotrypsin-like activity in the retina | Q35858136 |
| | Proteasome-dependent regulation of signal transduction in retinal pigment epithelial cells | Q36087272 |
| | RPE lipofuscin and its role in retinal pathobiology | Q36111032 |
| | VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. | Q36371399 |
| | Proteasome regulation of oxidative stress in aging and age-related diseases of the CNS. | Q36399788 |
| | Proteasomal defense of oxidative protein modifications. | Q36399794 |
| | Proteasome function in aging and oxidative stress: implications in protein maintenance failure | Q36399809 |
| | Oxidized protein degradation and repair in ageing and oxidative stress. | Q36435977 |
| | Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo | Q37360588 |
| | Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome | Q40361211 |
| | Protein oxidation and degradation during postmitotic senescence. | Q40363959 |
| | Selectivity of the ubiquitin pathway for oxidatively modified proteins: relevance to protein precipitation diseases | Q40385382 |
| | Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation. | Q40461698 |
| | Induction of vascular endothelial growth factor by 4-hydroxynonenal and its prevention by glutathione precursors in retinal pigment epithelial cells | Q40712203 |
| | Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins. | Q40804834 |
| | The triage of damaged proteins: degradation by the ubiquitin-proteasome pathway or repair by molecular chaperones. | Q40839196 |
| | Decreased levels of proteasome activity and proteasome expression in aging spinal cord | Q40873171 |
| | A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture. | Q40919605 |
| | Protection from oxidative inactivation of the 20S proteasome by heat-shock protein 90. | Q41027019 |
| | Redox regulation of ubiquitin-conjugating enzymes: mechanistic insights using the thiol-specific oxidant diamide | Q41045100 |
| | Accumulation of ubiquitinated proteins in mouse neuronal cells induced by oxidative stress | Q41121781 |
| | Growth hormone-induced signal tranduction depends on an intact ubiquitin system | Q41135290 |
| | Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7. | Q41183796 |
| | Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. | Q41190420 |
| | A comparison of ubiquitin-dependent proteolysis of rod outer segment proteins in reticulocyte lysate and a retinal pigment epithelial cell line | Q41300555 |
| | The photoreceptor G-protein transducin (Gt) is a substrate for ubiquitin-dependent proteolysis | Q41467646 |
| | Breakdown of oxidized proteins as a part of secondary antioxidant defenses in mammalian cells. | Q41565271 |
| | Targeting of substrates to the 26S proteasome | Q41641565 |
| | Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells | Q41913775 |
| | Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells | Q42506829 |
| | Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells | Q42826036 |
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3622-3630 | |
| P577 | publication date | 2008-04-11 | |
| P1433 | published in | Investigative Ophthalmology Visual Science | Q6060707 |
| P1476 | title | The proteasome: a target of oxidative damage in cultured human retina pigment epithelial cells | |
| P478 | volume | 49 | |