Calmodulin trapping by calcium-calmodulin-dependent protein kinase

scientific article published on May 22, 1992

Calmodulin trapping by calcium-calmodulin-dependent protein kinase is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1126/SCIENCE.256.5060.1199
P698PubMed publication ID1317063

P50authorTobias MeyerQ47504287
P2093author name stringL. Stryer
H. Schulman
P. I. Hanson
P2860cites workCa2+/calmodulin-dependent protein kinase II: identification of threonine-286 as the autophosphorylation site in the alpha subunit associated with the generation of Ca2+-independent activityQ24650135
Transient calcium release induced by successive increments of inositol 1,4,5-trisphosphateQ33589166
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independenceQ34338460
Neuronal Ca2+/calmodulin-dependent protein kinasesQ35231384
Serine/threonine kinases in the nervous systemQ37135314
Autophosphorylation of type II Ca2+/calmodulin-dependent protein kinase in cultures of postnatal rat hippocampal slicesQ37521698
Sequences of autophosphorylation sites in neuronal type II CaM kinase that control Ca2(+)-independent activityQ42148077
Phosphorylation of microtubule-associated proteins by a Ca2+/calmodulin-dependent protein kinaseQ42198091
Preparation of fluorescent, cross-linking, and biotinylated calmodulin derivatives and their use in studies of calmodulin-activated phosphodiesterase and protein phosphataseQ44265639
Structure and regulation of type II calcium/calmodulin-dependent protein kinase in central nervous system neuronsQ46188711
Expression of a multifunctional Ca2+/calmodulin-dependent protein kinase and mutational analysis of its autoregulationQ46224101
Reconstitution of calmodulin-sensitive adenylate cyclase from bovine brain with phospholipids, calmodulin, and beta-adrenergic receptorsQ48253126
P433issue5060
P407language of work or nameEnglishQ1860
P304page(s)1199-1202
P577publication date1992-05-01
1992-05-22
P1433published inScienceQ192864
P1476titleCalmodulin trapping by calcium-calmodulin-dependent protein kinase
P478volume256

Reverse relations

cites work (P2860)
Q428749905,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors
Q42813085A 60 kDa polypeptide of skeletal-muscle sarcoplasmic reticulum is a calmodulin-dependent protein kinase that associates with and phosphorylates several membrane proteins
Q37358555A Ca2+/calmodulin-dependent protein kinase required for symbiotic nodule development: Gene identification by transcript-based cloning
Q33948093A biophysical model of bidirectional synaptic plasticity: dependence on AMPA and NMDA receptors
Q28472847A dynamic model of interactions of Ca2+, calmodulin, and catalytic subunits of Ca2+/calmodulin-dependent protein kinase II
Q29620430A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation
Q34561492A fresh look at the role of CaMKII in hippocampal synaptic plasticity and memory
Q46508247A mechanism for Ca2+/calmodulin-dependent protein kinase II clustering at synaptic and nonsynaptic sites based on self-association.
Q47891862A mechanism for calmodulin (CaM) trapping by CaM-kinase II defined by a family of CaM-binding peptides
Q34017834A mechanism for synaptic frequency detection through autophosphorylation of CaM kinase II.
Q52080323A model for molecular mechanisms of synaptic competition for a finite resource.
Q37292998A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density
Q33913122A model of bidirectional synaptic plasticity: from signaling network to channel conductance
Q92205394A multi-state model of the CaMKII dodecamer suggests a role for calmodulin in maintenance of autophosphorylation
Q35039449A nitric oxide-independent and beta-adrenergic receptor-sensitive form of metaplasticity limits theta-frequency stimulation-induced LTP in the hippocampal CA1 region
Q39041994A novel calmodulin site in the Cav1.2 N-terminus regulates calcium-dependent inactivation
Q73704439A novel particulate form of Ca(2+)/calmodulin-dependent [correction of Ca(2+)/CaMKII-dependent] protein kinase II in neurons
Q48556747A novel protein phosphatase that dephosphorylates and regulates Ca2+/calmodulin-dependent protein kinase II.
Q30702659A novel receptor-mediated regulation mechanism of type I inositol polyphosphate 5-phosphatase by calcium/calmodulin-dependent protein kinase II phosphorylation
Q41722065A role for CaMKII in T cell memory
Q33736098A role for prefrontal calcium-sensitive protein phosphatase and kinase activities in working memory
Q34277824A significant but rather mild contribution of T286 autophosphorylation to Ca2+/CaM-stimulated CaMKII activity
Q36273111A theory of plasma membrane calcium pump stimulation and activity
Q27867688A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR.
Q34039498A working model of CaM kinase II activity in hippocampal long-term potentiation and memory
Q39681202Activated Ca2+/calmodulin-dependent protein kinase IIgamma is a critical regulator of myeloid leukemia cell proliferation
Q47824909Activation State-Dependent Substrate Gating in Ca2+/Calmodulin-Dependent Protein Kinase II.
Q40906776Activation of calcium/calmodulin-dependent kinase II following bovine rotavirus enterotoxin NSP4 expression.
Q41851301Activity-dependent modulation of limbic dopamine D3 receptors by CaMKII
Q39647635Alternative splicing modulates the frequency-dependent response of CaMKII to Ca(2+) oscillations
Q41644777Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.
Q59812964Analog Signaling With the "Digital" Molecular Switch CaMKII
Q37870268Analysis of CaM-kinase signaling in cells
Q64984224Architectural Dynamics of CaMKII-Actin Networks.
Q36650585Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signal
Q31961907Auto-inhibition of Ca(2+)/calmodulin-dependent protein kinase II by its ATP-binding domain.
Q49107159Autonomous activity and autophosphorylation of CAMPK-II in rat hippocampal slices: effects of tissue preparation
Q34435703Autophosphorylation of type II CaM kinase in hippocampal neurons: localization of phospho- and dephosphokinase with complementary phosphorylation site-specific antibodies
Q37705607Autophosphorylation-based Calcium (Ca2+) Sensitivity Priming and Ca2+/Calmodulin Inhibition of Arabidopsis thaliana Ca2+-dependent Protein Kinase 28 (CPK28).
Q34323982Autophosphorylation: a salient feature of protein kinases
Q41197577Basal phosphorylation of mu opioid receptor is agonist modulated and Ca2+-dependent
Q36210224Bi-directional regulation of CaMKIIα phosphorylation at Thr286 by NMDA receptors in cultured cortical neurons
Q96128036Binding of Filamentous Actin to CaMKII as Potential Regulation Mechanism of Bidirectional Synaptic Plasticity by β CaMKII in Cerebellar Purkinje Cells
Q38816511Biophysical analysis of the dynamics of calmodulin interactions with neurogranin and Ca2+ /calmodulin-dependent kinase II
Q48105788Biophysical attributes that affect CaMKII activation deduced with a novel spatial stochastic simulation approach
Q35039016CA1 long-term potentiation is diminished but present in hippocampal slices from alpha-CaMKII mutant mice
Q36544233CD147 reinforces [Ca2+]i oscillations and promotes oncogenic progression in hepatocellular carcinoma
Q34467864CREB signaling--timing is everything
Q38010169Ca(2+) sensor proteins in dendritic spines: a race for Ca(2+).
Q26796230Ca(2+) signaling in the myocardium by (redox) regulation of PKA/CaMKII
Q42815417Ca(2+)-calmodulin-dependent modification of smooth-muscle myosin light-chain kinase leading to its co-operative activation by calmodulin.
Q42442463Ca(2+)-independent autophosphorylation of postsynaptic density-associated Ca2+/calmodulin-dependent protein kinase
Q46677892Ca(2+)/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down
Q28344444Ca(2+)/calmodulin-dependent protein kinase mediates the phosphorylation of CD44 required for cell migration on hyaluronan
Q37157283Ca(2+)/calmodulin-dependent protein kinases
Q58172122Ca2+-calmodulin-dependent protein kinase expression and signalling in skeletal muscle during exercise
Q39714716Ca2+-dependent facilitation of Cav1.3 Ca2+ channels by densin and Ca2+/calmodulin-dependent protein kinase II.
Q35080382Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums
Q26830342Ca2+/calmodulin-dependent protein kinase II function in vascular remodelling
Q42505995CaM kinase II activation and phospholamban phosphorylation by SNP in murine gastric antrum smooth muscles
Q48579566CaM kinase II and visual input modulate memory formation in the neuronal circuit controlling courtship conditioning
Q33590606CaM kinase II in colonic smooth muscle contributes to dysmotility in murine DSS-colitis
Q41422701CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage
Q93140729CaMKII Activity in the Inflammatory Response of Cardiac Diseases
Q34280253CaMKII activation and dynamics are independent of the holoenzyme structure: an infinite subunit holoenzyme approximation
Q39226505CaMKII activity is reduced in skeletal muscle during sepsis
Q33885340CaMKII autonomy is substrate-dependent and further stimulated by Ca2+/calmodulin.
Q34069863CaMKII control of spine size and synaptic strength: role of phosphorylation states and nonenzymatic action
Q37833230CaMKII in myocardial hypertrophy and heart failure
Q37899670CaMKII in the cardiovascular system: sensing redox states.
Q26998988CaMKII oxidative activation and the pathogenesis of cardiac disease
Q36287751CaMKII regulation in information processing and storage
Q91003117CaMKII signaling in heart diseases: Emerging role in diabetic cardiomyopathy
Q25255889CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation
Q41092172CaMKII translocation requires local NMDA receptor-mediated Ca2+ signaling
Q36660431CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction.
Q37279355CaMKII-induced shift in modal gating explains L-type Ca(2+) current facilitation: a modeling study.
Q38181739CaMKII: claiming center stage in postsynaptic function and organization
Q28568161CaMKIIalpha interacts with M4 muscarinic receptors to control receptor and psychomotor function
Q35128346CaMKIIbeta association with the actin cytoskeleton is regulated by alternative splicing
Q42825689CaMKIIbeta functions as an F-actin targeting module that localizes CaMKIIalpha/beta heterooligomers to dendritic spines
Q36247125CaMKIIdelta overexpression in hypertrophy and heart failure: cellular consequences for excitation-contraction coupling
Q22008721Calbrain, a novel two EF-hand calcium-binding protein that suppresses Ca2+/calmodulin-dependent protein kinase II activity in the brain
Q21134074Calcium input frequency, duration and amplitude differentially modulate the relative activation of calcineurin and CaMKII
Q34578002Calcium oscillations
Q48553699Calcium signaling: up, down, up, down...what's the point?
Q35825862Calcium, kinases and nodulation signalling in legumes.
Q54113813Calcium/calmodulin-dependent kinase II and memory destabilization: a new role in memorymaintenance.
Q45969824Calcium/calmodulin-dependent protein kinase II mediates cardioprotection of intermittent hypoxia against ischemic-reperfusion-induced cardiac dysfunction.
Q54356691Calcium/calmodulin-dependent protein kinase II regulates cyclooxygenase-2 expression and prostaglandin E2 production by activating cAMP-response element-binding protein in rat peritoneal macrophages.
Q40637275Calcium/calmodulin-dependent protein kinase II: role in learning and memory
Q36669731Calmodulin and CaMKII as molecular switches for cardiac ion channels.
Q38333326Calmodulin and calmodulin-dependent kinase IIalpha regulate osteoblast differentiation by controlling c-fos expression
Q38105647Calmodulin in a heartbeat
Q34602616Calmodulin in action: diversity in target recognition and activation mechanisms.
Q39179475Calmodulin kinases: essential regulators in health and disease
Q30437877Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes
Q30473085Calmodulin regulation of Ca2+ entry in Jurkat T cells
Q42470136Calmodulin reverses rundown of L-type Ca(2+) channels in guinea pig ventricular myocytes
Q55287859Calmodulin shuttling mediates cytonuclear signaling to trigger experience-dependent transcription and memory.
Q28569500Calmodulin-binding peptide PEP-19 modulates activation of calmodulin kinase II In situ
Q26999872Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias
Q36749630Calreticulin inhibits commitment to adipocyte differentiation
Q33659776Cardiac Protection of Valsartan on Juvenile Rats with Heart Failure by Inhibiting Activity of CaMKII via Attenuating Phosphorylation.
Q37614035Cardiac calmodulin kinase: a potential target for drug design
Q34092385Cellular signaling through multifunctional Ca2+/calmodulin-dependent protein kinase II.
Q42160482Characterization of Ca2+/calmodulin-dependent protein kinase II from smooth muscle
Q28279720Characterization of the mechanism of regulation of Ca2+/ calmodulin-dependent protein kinase I by calmodulin and by Ca2+/calmodulin-dependent protein kinase kinase
Q35622415Chasing cardiac physiology and pathology down the CaMKII cascade
Q46056425Chemical quenched flow kinetic studies indicate an intraholoenzyme autophosphorylation mechanism for Ca2+/calmodulin-dependent protein kinase II.
Q45787586Competitive tuning: Competition's role in setting the frequency-dependence of Ca2+-dependent proteins
Q34979891Conformational changes underlying calcium/calmodulin-dependent protein kinase II activation
Q92440377Conformational coupling by trans-phosphorylation in calcium calmodulin dependent kinase II
Q40585986Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP.
Q29619261Control of memory formation through regulated expression of a CaMKII transgene
Q27641331Crystal structure of a tetradecameric assembly of the association domain of Ca2+/calmodulin-dependent kinase II
Q47997628Current theories of neuronal information processing performed by Ca2+/calmodulin-dependent protein kinase II with support and insights from computer modelling and simulation
Q44589911CyclinB1 expression is elevated and mitosis is delayed in HeLa cells expressing autonomous CaMKII
Q37000278Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites
Q36207510Decoding Ca2+ signals in plants
Q42478849Decoding Ca2+ signals to the nucleus by multifunctional CaM kinase.
Q37784580Decoding cytosolic Ca2+ oscillations
Q33572062Detailed state model of CaMKII activation and autophosphorylation
Q41240447Different mechanisms for Ca2+ dissociation from complexes of calmodulin with nitric oxide synthase or myosin light chain kinase
Q73419374Differential codes for free Ca(2+)-calmodulin signals in nucleus and cytosol
Q42976434Differential involvement of hippocampal calcineurin during learning and reversal learning in a Y-maze task
Q46711229Differential modulation of Ca2+/calmodulin-dependent protein kinase II activity by regulated interactions with N-methyl-D-aspartate receptor NR2B subunits and alpha-actinin
Q36741607Dissecting cooperative calmodulin binding to CaM kinase II: a detailed stochastic model
Q26823646Distinct roles of multiple isoforms of CaMKII in signaling to the nucleus
Q37105888Distribution of CaMKIIα expression in the brain in vivo, studied by CaMKIIα-GFP mice
Q38400771Does taurine prolong lifespan by improving heart function?
Q36173853Dual mechanism of a natural CaMKII inhibitor
Q35804436Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx
Q41871340Dynamic Kv4.3-CaMKII unit in heart: an intrinsic negative regulator for CaMKII activation
Q35551636Dynamic impact of temporal context of Ca²⁺ signals on inhibitory synaptic plasticity
Q40764549Dynamics of the calcium signal that triggers mammalian egg activation
Q33691114Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage
Q44230749Effect of (auto)phosphorylation on the kinetic behavior of the Ca2+/calmodulin-dependent protein kinase II from horse brain
Q36267572Effect of KN-62, a selective inhibitor of calmodulin-dependent kinase II, on mouse oocyte activation
Q41577496Effects of CaMKII inhibitor tatCN21 on activity-dependent redistribution of CaMKII in hippocampal neurons
Q48343920Enhanced calmodulin binding concurrent with increased kinase-dependent phosphorylation of cytoskeletal proteins following a single subcutaneous injection of diisopropyl phosphorofluoridate in hens
Q36430062Evolutionary and functional perspectives on signaling from neuronal surface to nucleus
Q30384588Fast Decay of CaMKII FRET Sensor Signal in Spines after LTP Induction Is Not Due to Its Dephosphorylation.
Q90155521Flexible linkers in CaMKII control the balance between activating and inhibitory autophosphorylation
Q36232889Fluorescence anisotropy imaging microscopy maps calmodulin binding during cellular contraction and locomotion
Q41110383Frequency-dependent inactivation of mammalian A-type K+ channel KV1.4 regulated by Ca2+/calmodulin-dependent protein kinase.
Q37822918From eggs to hearts: what is the link between cyclic ADP-ribose and ryanodine receptors?
Q52548721Functional diversity of alternatively spliced isoforms of Drosophila Ca2+/calmodulin-dependent protein kinase II. A role for the variable domain in activation.
Q41682758Functional implications of the subunit composition of neuronal CaM kinase II.
Q46882094Glutamate-induced glutamate release: a proposed mechanism for calcium bursting in astrocytes
Q28569210Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells
Q90062314Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O-linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes
Q48352249Identification of domains essential for the assembly of calcium/calmodulin-dependent protein kinase II holoenzymes
Q42536494Identification of the adenine binding site of the human A1 adenosine receptor
Q33913406In and out of the postsynaptic region: signalling proteins on the move
Q38733314In vitro reconstitution of a CaMKII memory switch by an NMDA receptor-derived peptide
Q49010346Inactivation and self-association of Ca2+/calmodulin-dependent protein kinase II during autophosphorylation
Q44300147Inactivation of ICa-L is the major determinant of use-dependent facilitation in rat cardiomyocytes.
Q33652643Inositol 1,3,4,5-tetrakisphosphate as a second messenger--a special role in neurones?
Q28534507Integration of biochemical and electrical signaling-multiscale model of the medium spiny neuron of the striatum
Q40791785Interaction with the NMDA receptor locks CaMKII in an active conformation
Q41887376Interactions between αCaMKII and calmodulin in living cells: conformational changes arising from CaM-dependent and -independent relationships
Q41441725Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase
Q97518928Intestinal Ca2+ absorption revisited: A molecular and clinical approach
Q39378745Intracellular Ca2+ Sensing: Its Role in Calcium Homeostasis and Signaling
Q37778392Intracellular Calcium Signaling Pathways during Liver Ischemia and Reperfusion
Q35121511Intracellular calmodulin availability accessed with two-photon cross-correlation
Q33886760Intracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes
Q48640343Introduction of a phosphate at serine741 of the calmodulin-binding domain of the neuronal nitric oxide synthase (NOS-I) prevents binding of calmodulin
Q45896367KN-93, A CaMKII inhibitor, suppresses ventricular arrhythmia induced by LQT2 without decreasing TDR.
Q73813727Kinetics of interaction of the myristoylated alanine-rich C kinase substrate, membranes, and calmodulin
Q39446733Link between fertilization-induced Ca2+ oscillations and relief from metaphase II arrest in mammalian eggs: a model based on calmodulin-dependent kinase II activation
Q37502868Localization of alpha type II calcium calmodulin-dependent protein kinase at glutamatergic but not gamma-aminobutyric acid (GABAergic) synapses in thalamus and cerebral cortex
Q42123449Long-term potentiation can be induced in the CA1 region of hippocampus in the absence of αCaMKII T286-autophosphorylation.
Q36343541Lymphocyte calcium signaling from membrane to nucleus
Q77521416MARCKS, membranes, and calmodulin: kinetics of their interaction
Q34178445Mechanisms for temporal tuning and filtering by postsynaptic signaling pathways
Q64930764Mechanisms of Ca2+/calmodulin-dependent kinase II activation in single dendritic spines.
Q38207020Mechanisms of CaMKII Activation in the Heart
Q35989578Mechanistic Investigation of the Arrhythmogenic Role of Oxidized CaMKII in the Heart
Q34774477Metabolic control of Ca2+/calmodulin-dependent protein kinase II (CaMKII)-mediated caspase-2 suppression by the B55β/protein phosphatase 2A (PP2A)
Q37695297Modeling CaMKII-mediated regulation of L-type Ca(2+) channels and ryanodine receptors in the heart.
Q38631812Modeling calcium regulation of contraction, energetics, signaling, and transcription in the cardiac myocyte.
Q73751392Models of calmodulin trapping and CaM kinase II activation in a dendritic spine
Q37965374Modulating protein activity and cellular function by methionine residue oxidation
Q51943924Modulatory effect of calmodulin-dependent kinase II (CaMKII) on sarcoplasmic reticulum Ca2+ handling and interval-force relations: a modelling study.
Q42157438Molecular and biochemical characterization of a calcium/calmodulin-binding protein kinase from rice
Q33842573Molecular and cellular mechanisms of cognitive function: implications for psychiatric disorders
Q40722220Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease
Q43625436Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II.
Q36879246Molecular mechanism of activation-triggered subunit exchange in Ca(2+)/calmodulin-dependent protein kinase II
Q33632550Molecular mechanisms of synaptic plasticity and memory.
Q52024852Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II.
Q40852756Multifunctional Ca2+/calmodulin-dependent protein kinase
Q36718669Multiple downstream proarrhythmic targets for calmodulin kinase II: moving beyond an ion channel-centric focus
Q44012222Multiple mechanisms for the potentiation of AMPA receptor-mediated transmission by alpha-Ca2+/calmodulin-dependent protein kinase II.
Q41728637NMDA-Dependent modulation of hippocampal kainate receptors by calcineurin and Ca(2+)/calmodulin-dependent protein kinase.
Q39294330Native and engineered sensors for Ca2+ and Zn2+: lessons from calmodulin and MTF1.
Q70921065Neurofilament phosphorylation and [125I]calmodulin binding by Ca2+/calmodulin-dependent protein kinase in the brain subcellular fractions of diisopropyl phosphorofluoridate (DFP)-treated hen
Q89619671Neurogranin Regulates Metaplasticity
Q34084407Neurogranin and synaptic plasticity balance
Q37328649Neurogranin enhances synaptic strength through its interaction with calmodulin
Q38356610Neuronal activity increases the phosphorylation of the transcription factor cAMP response element-binding protein (CREB) in rat hippocampus and cortex
Q35213163Nucleotides and phosphorylation bi-directionally modulate Ca2+/calmodulin-dependent protein kinase II (CaMKII) binding to the N-methyl-D-aspartate (NMDA) receptor subunit GluN2B.
Q26800197Ongoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray?
Q48546955Opposite regulation of inhibitory synaptic plasticity by α and β subunits of Ca(2+)/calmodulin-dependent protein kinase II.
Q55381387Physiological and unappreciated roles of CaMKII in the heart.
Q73854890Plant chimeric Ca2+/Calmodulin-dependent protein kinase. Role of the neural visinin-like domain in regulating autophosphorylation and calmodulin affinity
Q44542408Plasticity of mitochondrial calcium signaling
Q41549255Posttranslational modifications of calcium/calmodulin-dependent protein kinase IIδ and its downstream signaling in human failing hearts
Q37262277Prediction and validation of a mechanism to control the threshold for inhibitory synaptic plasticity.
Q48241596Presynaptic long-term depression at a central glutamatergic synapse: a role for CaMKII.
Q41064624Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor.
Q40347361Prior activation of inositol 1,4,5-trisphosphate receptors suppresses the subsequent induction of long-term potentiation in hippocampal CA1 neurons
Q28631532Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signals
Q42442490Protein kinase C-alpha attenuates cholinergically stimulated gastric acid secretion of rabbit parietal cells
Q38955489Proteomic Analysis of Postsynaptic Protein Complexes Underlying Neuronal Plasticity.
Q41480882Quantitative proteomics analysis of CaMKII phosphorylation and the CaMKII interactome in the mouse forebrain
Q41659791RC3/neurogranin, a postsynaptic calpacitin for setting the response threshold to calcium influxes
Q39660982Rate of diastolic Ca release from the sarcoplasmic reticulum of intact rabbit and rat ventricular myocytes
Q38196174Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology
Q39174495Redox regulation of the actin cytoskeleton and its role in the vascular system
Q37693592Reduced aerobic capacity causes leaky ryanodine receptors that trigger arrhythmia in a rat strain artificially selected and bred for low aerobic running capacity
Q58172108Regulation and function of Ca2+-calmodulin-dependent protein kinase II of fast-twitch rat skeletal muscle
Q37470331Regulation of CaMKII in vivo: the importance of targeting and the intracellular microenvironment
Q26785302Regulation of CaMKII signaling in cardiovascular disease
Q36102365Regulation of Ca²⁺/calmodulin-dependent protein kinase II signaling within hippocampal glutamatergic postsynapses during flurazepam withdrawal
Q40431849Regulation of Nuclear Calcium Concentration
Q35905032Regulation of calcium/calmodulin-dependent protein kinase II activation by intramolecular and intermolecular interactions.
Q43972704Regulation of exocytosis through Ca2+/ATP-dependent binding of autophosphorylated Ca2+/calmodulin-activated protein kinase II to syntaxin 1A.
Q35098759Regulation of gastrointestinal motility by Ca2+/calmodulin-stimulated protein kinase II.
Q37351713Regulation of intrasteric inhibition of the multifunctional calcium/calmodulin-dependent protein kinase
Q40605654Regulation of the Ca2+/CaM-responsive pool of CaMKII by scaffold-dependent autophosphorylation.
Q46681547Requirement of an allosteric kinetics of NMDA receptors for spike timing-dependent plasticity.
Q24323983Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart
Q41853774Role of the N- and C-lobes of calmodulin in the activation of Ca(2+)/calmodulin-dependent protein kinase II.
Q36283384S-Nitrosylation Induces Both Autonomous Activation and Inhibition of Calcium/Calmodulin-dependent Protein Kinase II δ.
Q28471682STDP in a bistable synapse model based on CaMKII and associated signaling pathways
Q28571729Selective regulation of neurite extension and synapse formation by the beta but not the alpha isoform of CaMKII
Q50469413Semi-continuous, label-free immunosensing approach for Ca2+-based conformation change of a calcium-binding protein.
Q47429353Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations: a simple model
Q33787712Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression
Q35852753Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding.
Q41952542Sisters Acts: Converging Signaling Between CaMKII and CaMKIV, Two Members of the Same Family
Q52235875Site-selective autophosphorylation of Ca2+/calmodulin-dependent protein kinase II as a synaptic encoding mechanism.
Q34286938Small proteins that modulate calmodulin-dependent signal transduction: effects of PEP-19, neuromodulin, and neurogranin on enzyme activation and cellular homeostasis
Q41897099Smooth muscle myosin light chain kinase, supramolecular organization, modulation of activity, and related conformational changes
Q48218278Spatial Ca2+ profiling: decrypting the universal cytosolic Ca2+ oscillation
Q46467681Spatial characteristics to calcium signalling; the calcium wave as a basic unit in plant cell calcium signalling
Q37008302Spatial diffusivity and availability of intracellular calmodulin
Q42509033Spike frequency decoding and autonomous activation of Ca2+-calmodulin-dependent protein kinase II in dorsal root ganglion neurons.
Q30306372Stimulation of unitary T-type Ca(2+) channel currents by calmodulin-dependent protein kinase II.
Q28478949Structural analysis and stochastic modelling suggest a mechanism for calmodulin trapping by CaMKII
Q27732611Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I
Q28143747Structural examination of autoregulation of multifunctional calcium/calmodulin-dependent protein kinase II
Q41210888Structure and regulation of calcium/calmodulin-dependent protein kinases II and IV.
Q24293502Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation
Q34586783Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II.
Q41733630Synaptic metaplasticity and the local charge effect in postsynaptic densities
Q41072017Synaptic plasticity: A molecular mechanism for metaplasticity
Q48246778Synaptic tagging and capture: differential role of distinct calcium/calmodulin kinases in protein synthesis-dependent long-term potentiation
Q42523168Targeted disruption of RC3 reveals a calmodulin-based mechanism for regulating metaplasticity in the hippocampus.
Q35599584Targeting of calcium/calmodulin-dependent protein kinase II.
Q46179717The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity, and Cardiac Function in Zebrafish
Q38060419The Ca-calmodulin dependent kinase II: a promising target for future antiarrhythmic therapies?
Q42431159The Calcium-Dependent Interaction of S100B with Its Protein Targets
Q64230497The Multi-Functional Calcium/Calmodulin Stimulated Protein Kinase (CaMK) Family: Emerging Targets for Anti-Cancer Therapeutic Intervention
Q50270869The calmodulin gene in Neurospora crassa is required for normal vegetative growth, ultraviolet survival, and sexual development
Q37078290The delicate bistability of CaMKII
Q33783785The effect of noise on CaMKII activation in a dendritic spine during LTP induction
Q26995205The emerging role of CaMKII in cancer
Q28243673The molecular mechanism of eukaryotic elongation factor 2 kinase activation
Q37020174The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors
Q38116041The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias
Q74589678The role of Ca2+/calmodulin-dependent protein kinases within the nucleus
Q38551638The role of CaMKII in diabetic heart dysfunction
Q37192039The role of calmodulin kinase II in myocardial physiology and disease
Q33957736Three ways to die suddenly: do they all require calcium calmodulin-dependent protein kinase II?
Q37459946Time-dependent autoinactivation of phospho-Thr286-alphaCa2+/calmodulin-dependent protein kinase II.
Q45987653Transient versus asymptotic dynamics of CaM kinase II: possible roles of phosphatase.
Q34190757Two-photon cross-correlation analysis of intracellular reactions with variable stoichiometry
Q92242463Unifying Long-Term Plasticity Rules for Excitatory Synapses by Modeling Dendrites of Cortical Pyramidal Neurons
Q35740668Unraveling the mystery of Nod factor signaling by a genomic approach in Medicago trunactula
Q40499514Vimentin rearrangement during African swine fever virus infection involves retrograde transport along microtubules and phosphorylation of vimentin by calcium calmodulin kinase II.
Q40442938Visualization of synaptic Ca2+ /calmodulin-dependent protein kinase II activity in living neurons.
Q30492990Visualizing dynamic interaction between calmodulin and calmodulin-related kinases via a monitoring method in live mammalian cells.
Q44258612alpha- and betaCaMKII. Inverse regulation by neuronal activity and opposing effects on synaptic strength
Q42236711alphaKAP is an anchoring protein for a novel CaM kinase II isoform in skeletal muscle.
Q38709548trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway.
Q34359499γCaMKII shuttles Ca²⁺/CaM to the nucleus to trigger CREB phosphorylation and gene expression

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