Loss of function and p53 protein stabilization

scientific article published on October 1997

Loss of function and p53 protein stabilization is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1032075271
P356DOI10.1038/SJ.ONC.1201374
P698PubMed publication ID9365234
P5875ResearchGate publication ID13865099

P50authorMikhail BlagosklonnyQ17517010
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)1889-1893
P577publication date1997-10-01
P1433published inOncogeneQ1568657
P1476titleLoss of function and p53 protein stabilization
P478volume15

Reverse relations

cites work (P2860)
Q44163171A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism
Q37492151A novel tumor-promoting role for nuclear factor IA in glioblastomas is mediated through negative regulation of p53, p21, and PAI1.
Q74529921A p53 genetic polymorphism as a modulator of hepatocellular carcinoma risk in relation to chronic liver disease, familial tendency, and cigarette smoking in hepatitis B carriers
Q40625177Abundant Expression of Spliced HDM2 in Hodgkin Lymphoma Cells does not Interfere with p14ARFand p53 Binding
Q34306523Anti-angiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture
Q97558454Association of Independent Prognostic Factors and Treatment Modality With Survival and Recurrence Outcomes in Breast Cancer
Q46788559Chaperone-dependent stabilization and degradation of p53 mutants
Q35833179Cisplatin fails to induce puma mediated apoptosis in mucosal melanomas
Q47627937Clinical evaluation of p53 mutations in urothelial carcinoma by IHC and FASAY.
Q54023194Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx.
Q33959840Concerted regulation of wild-type p53 nuclear accumulation and activation by S100B and calcium-dependent protein kinase C.
Q53072244Correlation of High-Risk Soft Tissue Sarcoma Biomarker Expression Patterns with Outcome following Neoadjuvant Chemoradiation.
Q44102640Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature-sensitive SV40 T antigen
Q34226063Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors
Q24529971Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.
Q37349459Epstein-Barr virus infection correlates with the expression of COX-2, p16(INK4A) and p53 in classic Hodgkin lymphoma
Q22254607Evidence that dynamin-2 functions as a signal-transducing GTPase
Q43816387FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3.
Q28361532Geldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperones
Q33961759High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays
Q34124337Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs
Q74284148Identification of p53 peptides recognized by CD8(+) T lymphocytes from patients with bladder cancer
Q36292668Immunohistochemical detection of p53 and Bcl-2 in colorectal carcinoma: no evidence for prognostic significance
Q46699154Inhibition of plasminogen activator inhibitor-1 expression in vascular smooth muscle cells by protoporphyrins through a heme oxygenase-independent mechanism
Q40794489Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: molecular determinants of paclitaxel-induced cytotoxicity
Q39170177Mechanisms of p53 restriction in Merkel cell carcinoma cells are independent of the Merkel cell polyoma virus T antigens.
Q40492947Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C.
Q44573111Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase
Q35574969Mutual reinforcement of inflammation and carcinogenesis by the Helicobacter pylori CagA oncoprotein
Q23922085NF-kappaB prevents cells from undergoing Cr(VI)-induced apoptosis
Q54941625Neuroblastoma Cell Lines Are Refractory to Genotoxic Drug-Mediated Induction of Ligands for NK Cell-Activating Receptors.
Q64269842Nucleotide variants and protein expression of TP53 in a Sri Lankan cohort of patients with head and neck cancer
Q34539978P53: an ubiquitous target of anticancer drugs
Q52826331Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer.
Q89449774Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients
Q36811577Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells
Q34340573Pigmentation, Melanocyte Colonization, and p53 Status in Basal Cell Carcinoma
Q53404887Pituitary neoplasia induced by expression of human neurotropic polyomavirus, JCV, early genome in transgenic mice.
Q35450753Poly(ADP-ribosyl)ation of p53 contributes to TPEN-induced neuronal apoptosis
Q26824536Predictive biomarkers in precision medicine and drug development against lung cancer
Q38931100Proteasome inhibitors suppress the protein expression of mutant p53.
Q35116243Proteomics: a strategy to understand the novel targets in protein misfolding and cancer therapy
Q41922591Regulation of BRCA1 by protein degradation
Q37730217Relationship between HPV and the biomarkers annexin A1 and p53 in oropharyngeal cancer
Q34740058Stabilization of p53 by CP-31398 inhibits ubiquitination without altering phosphorylation at serine 15 or 20 or MDM2 binding.
Q61806604Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells
Q92557155TIGAR promotes growth, survival and metastasis through oxidation resistance and AKT activation in glioblastoma
Q47298581The Tumor Suppressor p53 in Mucosal Melanoma of the Head and Neck
Q33771774The cellular response to p53: the decision between life and death
Q40258141The death domain kinase RIP has an important role in DNA damage-induced, p53-independent cell death
Q34096437The influence of Trp53 in the dose response of radiation-induced apoptosis, DNA repair and genomic stability in murine haematopoietic cells
Q73171130The stabilization mechanism of mutant-type p53 by impaired ubiquitination: the loss of wild-type p53 function and the hsp90 association
Q24550923ZBP-89 promotes growth arrest through stabilization of p53
Q35600102gef gene expression in MCF-7 breast cancer cells is associated with a better prognosis and induction of apoptosis by p53-mediated signaling pathway
Q34832663microRNAs: short non-coding bullets of gain of function mutant p53 proteins
Q77957211p53 induction in normal human skin in vitro following exposure to solar simulated UV and UV-B irradiation
Q45332864p53, HER2 and tumor cell apoptosis correlate with clinical outcome after neoadjuvant bevacizumab plus chemotherapy in breast cancer

Search more.