Biological characterization of human immunodeficiency virus type 1 and type 2 mutants in human peripheral blood mononuclear cells

scientific article published on January 1992

Biological characterization of human immunodeficiency virus type 1 and type 2 mutants in human peripheral blood mononuclear cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/BF01317146
P698PubMed publication ID1550494

P50authorHirofumi AkariQ38324069
P2093author name stringM Fukasawa
M Kawamura
K Tomonaga
T Miura
Y Takebe
J Sakuragi
M Hayami
T Shinjo
P2860cites workReplicative and cytopathic potential of HTLV-III/LAV with sor gene deletionsQ48367096
Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTRQ68097623
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular cloneQ29547734
SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeatQ29620254
VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytesQ33563208
Human immunodeficiency virus type 1 negative factor is a transcriptional silencerQ33836630
Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicityQ33929164
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cellsQ34048204
The trans-activator gene of HTLV-III is essential for virus replicationQ34161962
A second post-transcriptional trans-activator gene required for HTLV-III replicationQ34162178
Identification of HIV-1 vpr product and functionQ34168026
Functional role of human immunodeficiency virus type 1 vpu.Q34288200
Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1.Q34323971
Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitorQ34323995
Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replicationQ34603122
Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM).Q36800949
In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivityQ36825840
The art gene product of human immunodeficiency virus is required for replicationQ36827056
Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells.Q36829615
Characterization of a continuous T-cell line susceptible to the cytopathic effects of the acquired immunodeficiency syndrome (AIDS)-associated retrovirusQ37546388
Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity.Q40109393
Mutational analysis of the human immunodeficiency virus vpr open reading frame.Q40116997
Differential effects of nef on HIV replication: implications for viral pathogenesis in the hostQ41757870
Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirusQ42071857
A novel gene of HIV-1, vpu, and its 16-kilodalton productQ42656133
The trans-activator gene of the human T cell lymphotropic virus type III is required for replicationQ44579665
The sor gene of HIV-1 is required for efficient virus transmission in vitroQ45831189
The HIV 'A' (sor) gene product is essential for virus infectivityQ45847960
Generation and characterization of the human immunodeficiency virus type 1 mutantsQ45859881
Genomic divergence of HIV-2 from GhanaQ46381046
P433issue1-2
P304page(s)157-167
P577publication date1992-01-01
P1433published inArchives of VirologyQ2860564
P1476titleBiological characterization of human immunodeficiency virus type 1 and type 2 mutants in human peripheral blood mononuclear cells
P478volume123

Reverse relations

cites work (P2860)
Q35842465Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes
Q50740512Analysis of HIV-2 Vpx by modeling and insertional mutagenesis.
Q35852056Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes
Q33806688Cellular and viral specificities of human immunodeficiency virus type 1 vif protein
Q35868144Characterization of human immunodeficiency virus type 1 Vif particle incorporation
Q36994727Characterization of simian immunodeficiency virus SIVSM/human immunodeficiency virus type 2 Vpx function in human myeloid cells
Q35838106Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo
Q36629686Cysteine residues in the Vif protein of human immunodeficiency virus type 1 are essential for viral infectivity.
Q36654022Efficiency of viral DNA synthesis during infection of permissive and nonpermissive cells with vif-negative human immunodeficiency virus type 1
Q40478201Functional analysis of Vif protein shows less restriction of human immunodeficiency virus type 2 by APOBEC3G.
Q24682903HIV-1 Vpr interacts with a human 34-kDa mov34 homologue, a cellular factor linked to the G2/M phase transition of the mammalian cell cycle
Q64253074HUSH, a Link Between Intrinsic Immunity and HIV Latency
Q57178469Host cell-dependent replication of HIV-1 mutants with deletions in gp41 cytoplasmic tail region is independent of the function of Vif
Q41503378Human immunodeficiency virus Vpx is required for the early phase of replication in peripheral blood mononuclear cells
Q34465108Human immunodeficiency virus type 1 Vif is efficiently packaged into virions during productive but not chronic infection
Q33852465Human immunodeficiency virus type 1 Vif protein is packaged into the nucleoprotein complex through an interaction with viral genomic RNA.
Q24685633Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
Q34345408Intravirion processing of the human immunodeficiency virus type 1 Vif protein by the viral protease may be correlated with Vif function.
Q37728096Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?
Q24684633Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr
Q21131105New insights into an X-traordinary viral protein
Q35890940Nuclear import, virion incorporation, and cell cycle arrest/differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr.
Q36685112Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes
Q21131138SAMHD1-Dependent and -Independent Functions of HIV-2/SIV Vpx Protein
Q30417737SIV replication in human cells
Q40185026SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells
Q73890416Studies with GFP-Vpr fusion proteins: induction of apoptosis but ablation of cell-cycle arrest despite nuclear membrane or nuclear localization
Q36626506Subcellular localization of the Vif protein of human immunodeficiency virus type 1.
Q40467634The Human Immunodeficiency Virus Type 1 vif Gene: The Road from an Accessory to an Essential Role in Human Immunodeficiency Virus Type 1 Replication
Q35851966The Vif protein of human and simian immunodeficiency viruses is packaged into virions and associates with viral core structures.
Q40725617The genome of feline immunodeficiency virus.
Q40467618Viral Protein X
Q35866177vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus.

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