Adenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis

scientific article published on September 1997

Adenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/S0008-6363(97)00134-X
P698PubMed publication ID9415289

P2093author name stringGerard RD
Collen D
P2860cites workAdenoviral vector-mediated gene transfer into sheep arteries using a double-balloon catheterQ64383434
Genetic modification of the vessel wall. Comparison of surgical and catheter-based techniques for delivery of recombinant adenovirusQ64383540
Efficient and selective adenovirus-mediated gene transfer into vascular neointimaQ64383680
Characteristics of a human cell line transformed by DNA from human adenovirus type 5Q29547863
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene deliveryQ29615235
In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor geneQ34202163
Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genesQ34213104
Adenovirus-mediated transfer of a gene encoding cholesterol 7 alpha-hydroxylase into hamsters increases hepatic enzyme activity and reduces plasma total and low density lipoprotein cholesterolQ35752007
Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectorsQ35763533
Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplastyQ35766125
Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasiaQ35769081
Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal miceQ36201407
Cellular promoters incorporated into the adenovirus genome: cell specificity of albumin and immunoglobulin expressionQ36899070
Cellular promoters incorporated into the adenovirus genome: effects of viral regulatory elements on transcription rates and cell specificity of albumin and beta-globin promotersQ36899113
Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cellsQ37111501
Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endotheliumQ37351772
Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteriesQ37357232
Systemic hypertension induced by hepatic overexpression of human preproendothelin-1 in ratsQ37361568
Use of somatic gene transfer to study lipoprotein metabolism in experimental animals in vivoQ40922268
Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectorsQ40942254
Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.Q41237683
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transferQ41275978
Adenovirus-mediated transfer of a gene encoding human apolipoprotein A-I into normal mice increases circulating high-density lipoprotein cholesterolQ41443332
MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses.Q41664847
Potential gene therapy for lecithin-cholesterol acyltransferase (LCAT)-deficient and hypoalphalipoproteinemic patients with adenovirus-mediated transfer of human LCAT geneQ42526545
Gene therapy of hypercholesterolemic disorders.Q45866275
Phenotypic correction of hypercholesterolemia in apoE-deficient mice by adenovirus-mediated in vivo gene transferQ45869105
Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene productQ45869776
Percutaneous transluminal in vivo gene transfer by recombinant adenovirus in normal porcine coronary arteries, atherosclerotic arteries, and two models of coronary restenosisQ45871121
Gene therapy for vascular smooth muscle cell proliferation after arterial injuryQ45871893
Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor geneQ45877135
Hepatic expression of the catalytic subunit of the apolipoprotein B mRNA editing enzyme (apobec-1) ameliorates hypercholesterolemia in LDL receptor-deficient rabbitsQ45877600
Adenovirus-mediated in vivo gene transfer and expression in normal rat liverQ45878870
Gene transfer of cytidine deaminase apoBEC-1 lowers lipoprotein(a) in transgenic mice and induces apolipoprotein B editing in rabbitsQ46648715
Adenoviral mediated gene transfer to atherosclerotic arteries after balloon angioplasty.Q54611185
Physiological consequences of loss of plasminogen activator gene function in miceQ59069678
Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptorQ64382900
Local adenoviral-mediated expression of recombinant hirudin reduces neointima formation after arterial injuryQ64382923
Prevention of arterial thrombosis by adenovirus-mediated transfer of cyclooxygenase geneQ64383038
Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vectorQ64383065
Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vectorQ64383432
P433issue3
P921main subjectAdenoviridaeQ193447
gene therapyQ213901
thrombosisQ261327
hypercholesterolemiaQ762713
P304page(s)451-458
P577publication date1997-09-01
P1433published inCardiovascular ResearchQ4642329
P1476titleAdenovirus gene therapy for hypercholesterolemia, thrombosis and restenosis
P478volume35

Reverse relations

cites work (P2860)
Q36529815A mouse model for adenovirus gene delivery
Q35128370Adenovirus-mediated gene transfer in mesenchymal stem cells can be significantly enhanced by the cationic polymer polybrene
Q40073315Effects of Adenoviral Gene Transduction on the Stemness of Human Bone Marrow Mesenchymal Stem Cells.
Q36219334Helper-dependent adenoviral vectors in experimental gene therapy.
Q36049383MicroRNA silencing improves the tumor specificity of adenoviral transgene expression
Q43765577The prospects of hepatic drug delivery and gene therapy
Q58863311Therapeutic applications of serine protease inhibitors

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