The xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators

scientific article published on December 1999

The xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.274.52.36839
P698PubMed publication ID10601234
P5875ResearchGate publication ID30769968

P2093author name stringS X Wang
A Kumagai
W G Dunphy
D Patra
P2860cites workFunction of WW domains as phosphoserine- or phosphothreonine-binding modulesQ22008803
Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1Q24322626
The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1Q24533164
The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteinsQ24606249
Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switchQ27729296
Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependentQ27739821
The Cdk-associated protein Cks1 functions both in G1 and G2 in Saccharomyces cerevisiaeQ27935677
Cyclin-dependent kinases: engines, clocks, and microprocessorsQ29614786
Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targetsQ35203599
Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phaseQ37376960
Cell cycle regulation of a Xenopus Wee1-like kinaseQ37378230
Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activityQ40241310
Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosisQ40445615
Regulation of the cdc25 protein during the cell cycle in Xenopus extractsQ42612101
Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding proteinQ45293298
Cyclin activation of p34cdc2.Q46130213
Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.Q46903641
Xe-p9, a Xenopus Suc1/Cks homolog, has multiple essential roles in cell cycle controlQ46966617
Binding of activated cyclosome to p13(suc1). Use for affinity purificationQ48954881
Regulation of p34cdc2 protein kinase during mitosisQ69520047
Role of Suc1 in the activation of the cyclosome by protein kinase Cdk1/cyclin BQ74637771
P433issue52
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)36839-36842
P577publication date1999-12-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe xenopus Suc1/Cks protein promotes the phosphorylation of G(2)/M regulators
P478volume274

Reverse relations

cites work (P2860)
Q276312681H NMR study on the binding of Pin1 Trp-Trp domain with phosphothreonine peptides
Q46229708A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.
Q74440051A Cdc28 mutant uncouples G1 cyclin phosphorylation and ubiquitination from G1 cyclin proteolysis
Q36112179A Synthetic Dosage Lethal Genetic Interaction Between CKS1B and PLK1 Is Conserved in Yeast and Human Cancer Cells.
Q24305471A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1
Q57998240Assignment of the 1H, 13C and 15N resonances and secondary structure of the monomeric p13suc1 protein of Saccharomyces pombe
Q73873080Association of the cell cycle regulatory proteins p45(SKP2) and CksHs1. Functional effect on CDK2 complex formation and kinase activity
Q40030976CDK1 structures reveal conserved and unique features of the essential cell cycle CDK.
Q46856996CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of Treslin.
Q93110586CKS1 Germ Line Exclusion Is Essential for the Transition from Meiosis to Early Embryonic Development
Q33335574CKS1At overexpression in Arabidopsis thaliana inhibits growth by reducing meristem size and inhibiting cell-cycle progression.
Q24633046Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase
Q27680509Cks confers specificity to phosphorylation-dependent CDK signaling pathways
Q34577252Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.
Q27939842Cks1 is required for G(1) cyclin-cyclin-dependent kinase activity in budding yeast
Q37595393Cks1: Structure, Emerging Roles and Implications in Multiple Cancers
Q28611955Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C
Q43809033Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function
Q34999448Cyclin-dependent kinase homologues of Plasmodium falciparum
Q53240721Cyclin-dependent kinase-associated protein Cks2 is associated with bladder cancer progression.
Q28585746Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells
Q34455851Cyclin/Cdk complexes: their involvement in cell cycle progression and mitotic division
Q47069002Depletion of a Cks homolog in C. elegans embryos uncovers a post-metaphase role in both meiosis and mitosis
Q39392458Determinants for activation of the atypical AGC kinase Greatwall during M phase entry
Q37608398Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells
Q58325237Discrimination between serous low malignant potential and invasive epithelial ovarian tumors using molecular profiling
Q40511359Expression profiling of genes and proteins in HaCaT keratinocytes: proliferating versus differentiated state.
Q40793180Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression.
Q49106128Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network
Q53585069How tyrosine 15 phosphorylation inhibits the activity of cyclin-dependent kinase 2-cyclin A.
Q43296240Involvement of the dehydroleucodine alpha-methylene-gamma-lactone function in GVBD inhibition in Bufo arenarum oocytes
Q34009230Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes
Q37334970Loss of cks1 homeostasis deregulates cell division cycle
Q24679741MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner
Q64117127Mitochondrial Function of CKS2 Oncoprotein Links Oxidative Phosphorylation with Cell Division in Chemoradioresistant Cervical Cancer
Q46031560Molecular and biochemical characterization of the parvulin-type PPIases in Lotus japonicus.
Q28217310Molecular cloning and characterisation of p15(CDK-BP), a novel CDK-binding protein
Q36950539Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1.
Q41847977Multisite phosphorylation networks as signal processors for Cdk1.
Q34085749Oncogenic potential of a C.elegans cdc25 gene is demonstrated by a gain-of-function allele
Q28297156Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response
Q46921011Phosphorylation-dependent binding of cyclin B1 to a Cdc6-like domain of human separase.
Q73221725Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
Q28215887Pinning down proline-directed phosphorylation signaling
Q30575663Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for fibroblast growth factor 2 (FGF2)-induced osteoblast differentiation
Q34076832Regulation of the meiotic cell cycle in oocytes
Q42731247Regulatory dephosphorylation of CDK at G₂/M in plants: yeast mitotic phosphatase cdc25 induces cytokinin-like effects in transgenic tobacco morphogenesis
Q39410896Solution NMR study of the monomeric form of p13suc1 protein sheds light on the hinge region determining the affinity for a phosphorylated substrate
Q58762403Structural insights into the functional diversity of the CDK-cyclin family
Q49117736Systematic localization of the Arabidopsis core cell cycle proteins reveals novel cell division complexes
Q36353395Targeting Conformational Activation of CDK2 Kinase
Q28749570The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit
Q37501709The CDK subunit CKS2 counteracts CKS1 to control cyclin A/CDK2 activity in maintaining replicative fidelity and neurodevelopment.
Q37055702The Prozone Effect Accounts for the Paradoxical Function of the Cdk-Binding Protein Suc1/Cks
Q35164326The biochemistry of mitosis
Q28202908The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
Q40212919The cyclin dependent kinase subunit Cks1 is required for infection-associated development of the rice blast fungus Magnaporthe oryzae
Q24795560The prolyl isomerase Pin1 in breast development and cancer
Q28215946Three different binding sites of Cks1 are required for p27-ubiquitin ligation
Q30634834Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain.
Q43507734p13(SUC1) and the WW domain of PIN1 bind to the same phosphothreonine-proline epitope
Q60200100p27 destruction: Cks1 pulls the trigger

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