Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light

scientific article published on December 1990

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.172.6.1609
P932PMC publication ID2188768
P698PubMed publication ID2258696

P2093author name stringAnsel JC
Schwarz T
Luger TA
Kirnbauer R
Urbanski A
Köck A
Perry P
P2860cites workMacrophages as a source of tumoricidal activity (tumor-necrotizing factor).Q33910830
Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factorsQ34195478
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxinQ34258651
Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitroQ35586782
Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitroQ36349915
Tumor necrosis factor alpha maintains the viability of murine epidermal Langerhans cells in culture, but in contrast to granulocyte/macrophage colony-stimulating factor, without inducing their functional maturationQ36350184
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblastsQ36351406
Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1Q36351889
Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1Q36351905
Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.Q36353242
Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cellsQ36354420
Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host diseaseQ36357597
Effect of UV irradiation on epidermal cell cytokine productionQ38237294
Cachectin and tumour necrosis factor as two sides of the same biological coinQ39501245
Supergene families meet in the immune systemQ39579905
The role of cachectin/TNF in endotoxic shock and cachexiaQ39580667
Cachectin: more than a tumor necrosis factorQ39755392
Immunological Unresponsiveness Induced by Ultraviolet RadiationQ40118273
Ultraviolet light induces increased circulating interleukin-6 in humansQ40761533
IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell linesQ40776887
Immunohistological detection of interleukin I-like molecules and tumour necrosis factor in human epidermis before and after UVB-irradiation in vivoQ42515794
In vitro anti-human immunodeficiency virus activities of tumor necrosis factor-alpha and interferon-gamma.Q45833893
Binding of recombinant interleukin-1 beta to the third complement component and alpha 2-macroglobulin after activation of serum by immune complexesQ67660827
The expression and modulation of IL-1 alpha in murine keratinocytesQ68092034
Serum-free in vitro bioassay for the detection of tumor necrosis factorQ69644439
Potentiation of lymphokine-induced macrophage activation by tumor necrosis factor-alphaQ70379218
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectultraviolet radiationQ11391
endotoxinsQ319997
keratinocyteQ1473931
P304page(s)1609-1614
P577publication date1990-12-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleHuman keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light
P478volume172