Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain

scientific article published on 22 March 2016

Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/AJMG.B.32445
P932PMC publication ID4988385
P698PubMed publication ID27004590

P50authorDeepak P. SrivastavaQ30505238
Robin MurrayQ7352679
Claire TroakesQ43128433
Nicholas BrayQ57419559
P2093author name stringMatthew Nolan
Rodrigo R R Duarte
P2860cites workAbundant quantitative trait loci exist for DNA methylation and gene expression in human brainQ21563315
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Haploview: analysis and visualization of LD and haplotype mapsQ27860955
Genome-wide association study identifies five new schizophrenia lociQ28248384
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Spatio-temporal transcriptome of the human brainQ29614572
The long-range interaction landscape of gene promotersQ29615403
Implications of normal brain development for the pathogenesis of schizophreniaQ29618740
Genetic variability in the regulation of gene expression in ten regions of the human brainQ34398489
A role for noncoding variation in schizophreniaQ34632245
Effects of cis-regulatory variation differ across regions of the adult human brainQ35819825
Methylation QTLs in the developing brain and their enrichment in schizophrenia risk lociQ36466426
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorderQ37571848
Role of arsenic (+3 oxidation state) methyltransferase in arsenic metabolism and toxicity.Q38057563
Enzymatic properties and physiological roles of cytosolic 5'-nucleotidase II.Q38132865
A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brainQ42928107
Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.Q48224902
Evidence that schizophrenia risk variation in the ZNF804A gene exerts its effects during fetal brain developmentQ48266548
Cis-acting variation in the expression of a high proportion of genes in human brainQ48319040
Investigation of the prenatal expression patterns of 108 schizophrenia-associated genetic lociQ48374602
Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.Q53621277
Allelic Variation in Human Gene ExpressionQ57293497
Schizophrenia: a purinergic hypothesisQ73735508
P433issue6
P921main subjectschizophreniaQ41112
P304page(s)806-814
P577publication date2016-03-22
P1433published inAmerican Journal of Medical Genetics Part B: Neuropsychiatric GeneticsQ15762380
P1476titleGenome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain
P478volume171

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cites work (P2860)
Q33905647Altered Brain Network Connectivity as a Potential Endophenotype of Schizophrenia
Q42126457BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon
Q94521602Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders
Q58562545Expanding the clinical relevance of the 5'-nucleotidase cN-II/NT5C2
Q92002421Identification of a functional 339 bp Alu insertion polymorphism in the schizophrenia-associated locus at 10q24.32
Q38995568Mechanisms and functions of lysosome positioning
Q45976861Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.
Q52568181Novel Aspects of Renal Magnesium Homeostasis.
Q92087685The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells
Q92058260The VNTR of the AS3MT gene is associated with brain activations during a memory span task and their training-induced plasticity
Q90469774The genetic architecture of the human cerebral cortex

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