Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase

scientific article published on 9 July 2015

Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MOLCEL.2015.06.009
P932PMC publication ID5602610
P698PubMed publication ID26166702

P2093author name stringChristopher J Shoemaker
Vladimir Denic
Roarke A Kamber
P2860cites workBinding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagyQ24295813
Autophagic clearance of polyQ proteins mediated by ubiquitin-Atg8 adaptors of the conserved CUET protein familyQ24301029
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growthQ24304447
Hsp90-Cdc37 chaperone complex regulates Ulk1- and Atg13-mediated mitophagyQ24323790
The Cvt pathway as a model for selective autophagyQ24617191
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cellsQ24648105
Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuoleQ24680389
Tor-mediated induction of autophagy via an Apg1 protein kinase complexQ24685670
Structure of the human autophagy initiating kinase ULK1 in complex with potent inhibitors.Q43113513
Degradation of Paternal Mitochondria by Fertilization-Triggered Autophagy in C. elegans EmbryosQ48663199
Selective autophagy regulates insertional mutagenesis by the Ty1 retrotransposon in Saccharomyces cerevisiaeQ50514448
Architecture of the Atg17 Complex as a Scaffold for Autophagosome BiogenesisQ27675392
Mechanism of cargo selection in the cytoplasm to vacuole targeting pathwayQ27930198
Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.Q27931961
Hrr25 kinase promotes selective autophagy by phosphorylating the cargo receptor Atg19.Q27933867
A ubiquitin-like system mediates protein lipidationQ27934137
Aspartyl Aminopeptidase Is Imported from the Cytoplasm to the Vacuole by Selective Autophagy in Saccharomyces cerevisiaeQ27934838
Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathwayQ27938129
Hrr25 triggers selective autophagy-related pathways by phosphorylating receptor proteinsQ27939298
Lap3 is a selective target of autophagy in yeast, Saccharomyces cerevisiaeQ27940228
Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiaeQ27940258
Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting pathwayQ27940322
Huntingtin functions as a scaffold for selective macroautophagyQ28118022
Suppression of basal autophagy in neural cells causes neurodegenerative disease in miceQ28131756
Loss of autophagy in the central nervous system causes neurodegeneration in miceQ28131804
Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmissionQ28585127
Potential function for the Huntingtin protein as a scaffold for selective autophagyQ30301372
Tor directly controls the Atg1 kinase complex to regulate autophagyQ33627273
Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila.Q33831320
Autophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiaeQ34007927
A semisynthetic epitope for kinase substrates.Q34100971
One-step affinity purification of the yeast ribosome and its associated proteins and mRNAsQ34364591
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.Q34399968
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.Q34728044
Design and use of analog-sensitive protein kinasesQ34748885
Receptor proteins in selective autophagyQ35872411
The scaffold protein EPG-7 links cargo-receptor complexes with the autophagic assembly machinery.Q36732763
Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopyQ36749625
The Tor and PKA signaling pathways independently target the Atg1/Atg13 protein kinase complex to control autophagyQ37386075
Early steps in autophagy depend on direct phosphorylation of Atg9 by the Atg1 kinase.Q37690122
Substrate recognition in selective autophagy and the ubiquitin-proteasome system.Q38094868
Cargo binding to Atg19 unmasks additional Atg8 binding sites to mediate membrane-cargo apposition during selective autophagy.Q39191335
An auxin-based degron system for the rapid depletion of proteins in nonplant cells.Q39774277
Escape of intracellular Shigella from autophagyQ40485419
Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiaeQ41792153
Deficiency of the exportomer components Pex1, Pex6, and Pex15 causes enhanced pexophagy in Saccharomyces cerevisiaeQ42272085
Activation of Atg1 kinase in autophagy by regulated phosphorylationQ42856467
Atg23 and Atg27 act at the early stages of Atg9 trafficking in S. cerevisiaeQ43091559
P433issue3
P921main subjectautophagyQ288322
P304page(s)372-381
P577publication date2015-07-09
P1433published inMolecular CellQ3319468
P1476titleReceptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase
P478volume59

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cites work (P2860)
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Q99254866Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation
Q92252018Atg11 tethers Atg9 vesicles to initiate selective autophagy
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Q47241715CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
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