Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum

scientific article published on February 1998

Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0945-053X(98)90011-7
P698PubMed publication ID9524358

P2093author name stringNagata K
P2860cites workHSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activatorQ24308493
Isolation, characterization and chromosomal assignment of human colligin-2 gene (CBP2)Q24336324
HSP47: a tissue-specific, transformation-sensitive, collagen-binding heat shock protein of chicken embryo fibroblastsQ24597841
A C-terminal signal prevents secretion of luminal ER proteinsQ29618994
Molecular cloning of a mouse 47‐kDa heat‐shock protein (HSP47), a collagen‐binding stress protein, and its expression during the differentiation of F9 teratocarcinoma cellsQ30983377
Speculations on the functions of the major heat shock and glucose-regulated proteinsQ34562570
A major collagen-binding protein of chick embryo fibroblasts is a novel heat shock proteinQ36213068
pH-dependent function, purification, and intracellular location of a major collagen-binding glycoproteinQ36218058
Posttranslational folding of vesicular stomatitis virus G protein in the ER: involvement of noncovalent and covalent complexesQ36232426
Parallel regulation of procollagen I and colligin, a collagen-binding protein and a member of the serine protease inhibitor familyQ36233183
Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulumQ36531375
Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathwayQ36677534
Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP.Q36721098
Intracellular interaction of collagen-specific stress protein HSP47 with newly synthesized procollagenQ36796732
Distinct patterns of glycosylation of colligin, a collagen-binding glycoprotein, and SPARC (osteonectin), a secreted Ca2+-binding glycoprotein. Evidence for the localisation of colligin in the endoplasmic reticulumQ38349627
Coexpression of the collagen-binding stress protein HSP47 gene and the alpha 1(I) and alpha 1(III) collagen genes in carbon tetrachloride-induced rat liver fibrosisQ40513019
Endoplasmic reticulum protein Hsp47 binds specifically to the N-terminal globular domain of the amino-propeptide of the procollagen I alpha 1 (I)-chain.Q41276168
Hsp47 and cyclophilin B traverse the endoplasmic reticulum with procollagen into pre-Golgi intermediate vesicles. A role for Hsp47 and cyclophilin B in the export of procollagen from the endoplasmic reticulumQ41313457
Regulation of J6 gene expression by transcription factor GATA-4.Q41354071
Inhibition of procollagen I degradation by colligin: a collagen-binding serpinQ41437680
Regulation and function of collagen-specific molecular chaperone, HSP47.Q41444793
Distribution of the collagen binding heat-shock protein in chicken tissuesQ42461210
Identification of the molecular recognition sequence which determines the type-specific assembly of procollagenQ42611445
Structure of the gene encoding the mouse 47-kDa heat-shock protein (HSP47).Q42810253
Differentiation defective mutants of skeletal myoblasts altered in a gelatin-binding glycoprotein.Q54400956
Peptide-binding specificity of the molecular chaperone BiPQ59071395
Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unitQ69392715
Folding mechanism of the triple helix in type-III collagen and type-III pN-collagen. Role of disulfide bridges and peptide bond isomerizationQ71264947
Hsp 47 is localized to regions of type I collagen production in developing murine femurs and molarsQ72678495
P433issue7
P921main subjectendoplasmic reticulumQ79927
molecular chaperonesQ422496
P304page(s)379-386
P577publication date1998-02-01
P1433published inMatrix BiologyQ6787851
P1476titleExpression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum
P478volume16

Reverse relations

cites work (P2860)
Q37353099Advances in antifibrotic therapy
Q34769458Angiotensin II type 1 receptor antagonist attenuates lacrimal gland, lung, and liver fibrosis in a murine model of chronic graft-versus-host disease
Q41609453Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood
Q52102300Antisense oligonucleotide against 47-kDa heat shock protein (Hsp47) inhibits wound-induced enhancement of collagen production.
Q35808541Antisense oligonucleotide inhibition of heat shock protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats
Q58214930Assembly of Type IV Collagen
Q48105507Association between heat stress protein 70 induction and decreased pulmonary fibrosis in an animal model of acute lung injury
Q34815474Chaperones and aging: role in neurodegeneration and in other civilizational diseases
Q48268560Coexpression of HSP47 gene and type I and type III collagen genes in LPS-induced pulmonary fibrosis in rats
Q34224267Collagens and collagen-related diseases
Q40987019Contribution of reactive oxygen species to the pathogenesis of pulmonary arterial hypertension
Q53793034Cu,Zn-SOD deficiency induces the accumulation of hepatic collagen.
Q33805051Effect of CO₂ laser irradiation on wound healing of exposed rat pulp
Q51569921Effects of heat stress on respiratory burst, oxidative damage and SERPINH1 (HSP47) mRNA expression in rainbow trout Oncorhynchus mykiss.
Q24685719Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis
Q36176591Endoplasmic reticulum remains continuous and undergoes sheet-to-tubule transformation during cell division in mammalian cells
Q43016305Endoplasmic reticulum stress inhibits collagen synthesis independent of collagen-modifying enzymes in different chondrocyte populations and dermal fibroblasts
Q37849269Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?
Q94595628Expression of Collagen (Types I, III, and V), HSP47, MMP-2, and TIMP-1 in Retrobulbar Adipose Tissue of Patients with Thyroid-Associated Orbitopathy
Q43919357Expression of heat shock proteins in a linear rodent wound
Q47811232Expression of small heat shock protein alphaB-crystallin is induced after hepatic stellate cell activation
Q34361328Glial expression of heat shock proteins (HSPs) and oxygen-regulated proteins (ORPs).
Q42519471Glial expression of small heat shock proteins following an excitotoxic lesion in the immature rat brain
Q73828749HSP47 binds cooperatively to triple helical type I collagen but has little effect on the thermal stability or rate of refolding
Q48036158HSP47 is a useful marker for skin fibroblasts in formalin-fixed, paraffin-embedded tissue specimens
Q36309370HSP47 regulates ECM accumulation in renal proximal tubular cells induced by TGF-β1 through ERK1/2 and JNK MAPK pathways
Q39612973Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells
Q34911441Heat shock proteins modulate keloid formation
Q33591934Heat-shock protein protection.
Q36544243Immunoexpression of α2-integrin and Hsp47 in hereditary gingival fibromatosis and gingival fibromatosis-associated dental abnormalities
Q33809828Influence of heating and cyclic tension on the induction of heat shock proteins and bone-related proteins by MC3T3-E1 cells
Q55007717Integrated Stress Response and Decreased ECM in Cultured Stromal Cells From Keratoconus Corneas.
Q28294669Interactions of heat shock protein 47 with collagen and the stress response: An unconventional chaperone model?
Q33203014Intracellular trafficking and degradation of unassociated proalpha2 chains of collagen type I.
Q35862865Involvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis
Q35859447Molecular Consequences of the SERPINH1/HSP47 Mutation in the Dachshund Natural Model of Osteogenesis Imperfecta
Q31105163Molecular and cell biology of porcine HSP47 during wound healing: complete cDNA sequence and regulation of gene expression
Q44420367Molecular and cell biology of skin wound healing in a pig model
Q35159020Molecular mimicry in atherosclerosis: a role for heat shock proteins in immunisation
Q58604208Mutual interaction between oxidative stress and endoplasmic reticulum stress in the pathogenesis of diseases specifically focusing on non-alcoholic fatty liver disease
Q52085174Peripheral blood fibrocytes contribute to the formation of the avian spleen.
Q35791840Persistent down-regulation of Fli1, a suppressor of collagen transcription, in fibrotic scleroderma skin
Q45280998Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu
Q40903724Procollagen binds to both prolyl 4-hydroxylase/protein disulfide isomerase and HSP47 within the endoplasmic reticulum in the absence of ascorbate
Q47876110RNA differential display of scarless wound healing in fetal rabbit indicates downregulation of a CCT chaperonin subunit and upregulation of a glycophorin-like gene transcript
Q46674198Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone
Q35706272Response of a preosteoblastic cell line to cyclic tensile stress conditioning and growth factors for bone tissue engineering
Q35739984Response of preosteoblasts to thermal stress conditioning and osteoinductive growth factors
Q34411209Role of heat shock protein 47 in transdifferentiation of human tenon's fibroblasts to myofibroblasts.
Q44052070Role of heat shock protein 47 on tubulointerstitium in experimental radiation nephropathy
Q44609791Selective depletion of fibroblasts preserves morphology and the functional integrity of peritoneum in transgenic mice with peritoneal fibrosing syndrome
Q41818129Self-assembly of prevascular tissues from endothelial and fibroblast cells under scaffold-free, nonadherent conditions
Q42997173Structure-function studies on hsp47: pH-dependent inhibition of collagen fibril formation in vitro
Q48022737Substrate specificity in the context of molecular chaperones.
Q93166454Targeted delivery of hyaluronic acid nanomicelles to hepatic stellate cells in hepatic fibrosis rats
Q35102837Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma
Q81026436Targeting siRNA to arrest fibrosis
Q91625064The beginning of a new era: treatment of erectile dysfunction by use of physical energies as an alternative to pharmaceuticals
Q46309289The cld mutation: narrowing the critical chromosomal region and selecting candidate genes
Q77162067The globular domain of the proalpha 1(I) N-propeptide is not required for secretion, processing by procollagen N-proteinase, or fibrillogenesis of type I collagen in mice
Q44115754The renal expression of heat shock protein 47 and collagens in acute and chronic experimental diabetes in rats
Q36338176The role of collagen in bone strength
Q35077321Toxicogenomics profiling of bone marrow from rats treated with topotecan in combination with oxaliplatin: a mechanistic strategy to inform combination toxicity
Q77490706Use of collagen sponge incorporating transforming growth factor-beta1 to promote bone repair in skull defects in rabbits
Q24673098VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo
Q36078314Wound healing profiles of hyperopic-small incision lenticule extraction (SMILE).
Q93055648siRNA- and miRNA-based therapeutics for liver fibrosis

Search more.