Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses

scientific article published on January 2012

Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.5191-11.2012
P932PMC publication ID3342858
P698PubMed publication ID22262888
P5875ResearchGate publication ID221764393

P50authorStéphanie BaulacQ47402324
P2093author name stringXuan Wang
Dawei Zhang
Ekim Ozkaynak
Ekkehard M Kasper
Yu-Dong Zhou
Eric Leguern
Matthew P Anderson
P2860cites workLGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibitionQ24312114
Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory featuresQ24643177
Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous systemQ24650727
LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathwayQ28253059
The classical complement cascade mediates CNS synapse eliminationQ28261273
Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmissionQ28264840
Experience-driven plasticity of visual cortex limited by myelin and Nogo receptorQ28274782
ADPEAF mutations reduce levels of secreted LGI1, a putative tumor suppressor protein linked to epilepsyQ28506819
Functional interaction between matrix metalloproteinase-3 and semaphorin-3C during cortical axonal growth and guidanceQ28506945
Abnormal functional organization in the dorsal lateral geniculate nucleus of mice lacking the beta 2 subunit of the nicotinic acetylcholine receptorQ28509430
Visual response properties in the dorsal lateral geniculate nucleus of mice lacking the beta2 subunit of the nicotinic acetylcholine receptorQ28511869
The epilepsy-linked Lgi1 protein assembles into presynaptic Kv1 channels and inhibits inactivation by Kvbeta1Q28567361
In vivo time-lapse imaging and serial section electron microscopy reveal developmental synaptic rearrangementsQ30428647
Activity patterns govern synapse-specific AMPA receptor trafficking between deliverable and synaptic poolsQ30439413
Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice.Q30479847
Enhanced synaptic connectivity and epilepsy in C1q knockout miceQ30494456
Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway.Q33653166
Synapse elimination and indelible memoryQ33864501
Long-term depression in the CNS.Q34121481
Emergence of lamina-specific retinal ganglion cell connectivity by axon arbor retraction and synapse eliminationQ34777417
Synaptic development of the mouse dorsal lateral geniculate nucleusQ34783980
Experience-dependent retinogeniculate synapse remodeling is abnormal in MeCP2-deficient miceQ34856164
Axon retraction and degeneration in development and diseaseQ36196519
Spontaneous patterned retinal activity and the refinement of retinal projectionsQ36310213
Organization and remodeling of the olivocerebellar climbing fiber projectionQ36417573
Refinement of the retinogeniculate pathwayQ37192008
Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy.Q37381254
LGI1 mutations in autosomal dominant and sporadic lateral temporal epilepsy.Q37384880
Synapse elimination in the central nervous systemQ37501163
Wiring and rewiring of the retinogeniculate synapseQ37874006
Arrested glutamatergic synapse development in human partial epilepsyQ41131473
Vision triggers an experience-dependent sensitive period at the retinogeniculate synapseQ42054778
Developmental remodelling of the lemniscal synapse in the ventral basal thalamus of the mouse.Q42492907
Development of single retinofugal axon arbors in normal and β2 knock-out miceQ42700713
Structural and functional composition of the developing retinogeniculate pathway in the mouseQ46839109
Distinct roles for spontaneous and visual activity in remodeling of the retinogeniculate synapseQ48394935
Failure to maintain eye-specific segregation in nob, a mutant with abnormally patterned retinal activityQ48573266
Developmental remodeling of the retinogeniculate synapse.Q49063133
Synaptic dynamism measured over minutes to months: age-dependent decline in an autonomic ganglion.Q52006102
In vivo time-lapse imaging of synaptic takeover associated with naturally occurring synapse eliminationQ78789949
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)903-910
P577publication date2012-01-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleEpilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses
P478volume32

Reverse relations

cites work (P2860)
Q38710287Autoimmune synaptopathies
Q35834299Axon targeting of the alpha 7 nicotinic receptor in developing hippocampal neurons by Gprin1 regulates growth
Q55456679Clinical characteristics and short-term prognosis of LGI1 antibody encephalitis: a retrospective case study.
Q34370543Epigenomic profiling of men exposed to early-life stress reveals DNA methylation differences in association with current mental state
Q47952463Errant gardeners: glial-cell-dependent synaptic pruning and neurodevelopmental disorders
Q38012351Genetics of epilepsy and relevance to current practice
Q27303973Glutamatergic neuron-targeted loss of LGI1 epilepsy gene results in seizures
Q26998200LGI proteins in the nervous system
Q36583967LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development
Q38695397LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels.
Q90193710Relevance of Surface Neuronal Protein Autoantibodies as Biomarkers in Seizure-Associated Disorders
Q30475064The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development

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